These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

365 related articles for article (PubMed ID: 24695755)

  • 1. Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA.
    Maji B; Bhattacharya S
    Chem Commun (Camb); 2014 Jun; 50(49):6422-38. PubMed ID: 24695755
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition.
    Bhattacharya S; Chaudhuri P; Jain AK; Paul A
    Bioconjug Chem; 2010 Jul; 21(7):1148-59. PubMed ID: 20536245
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Affinity and selectivity of G4 ligands measured by FRET.
    De Cian A; Guittat L; Shin-ya K; Riou JF; Mergny JL
    Nucleic Acids Symp Ser (Oxf); 2005; (49):235-6. PubMed ID: 17150720
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting telomeres and telomerase.
    De Cian A; Lacroix L; Douarre C; Temime-Smaali N; Trentesaux C; Riou JF; Mergny JL
    Biochimie; 2008 Jan; 90(1):131-55. PubMed ID: 17822826
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Telomere maintenance as a target for drug discovery.
    Sekaran V; Soares J; Jarstfer MB
    J Med Chem; 2014 Feb; 57(3):521-38. PubMed ID: 24053596
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rational design of acridine-based ligands with selectivity for human telomeric quadruplexes.
    Sparapani S; Haider SM; Doria F; Gunaratnam M; Neidle S
    J Am Chem Soc; 2010 Sep; 132(35):12263-72. PubMed ID: 20718414
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis for telomeric G-quadruplex targeting by naphthalene diimide ligands.
    Collie GW; Promontorio R; Hampel SM; Micco M; Neidle S; Parkinson GN
    J Am Chem Soc; 2012 Feb; 134(5):2723-31. PubMed ID: 22280460
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fluorescence-based melting assays for studying quadruplex ligands.
    De Cian A; Guittat L; Kaiser M; SaccĂ  B; Amrane S; Bourdoncle A; Alberti P; Teulade-Fichou MP; Lacroix L; Mergny JL
    Methods; 2007 Jun; 42(2):183-95. PubMed ID: 17472900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reduced or diminished stabilization of the telomere G-quadruplex and inhibition of telomerase by small chemical ligands under molecular crowding condition.
    Chen Z; Zheng KW; Hao YH; Tan Z
    J Am Chem Soc; 2009 Aug; 131(30):10430-8. PubMed ID: 19588966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of new benzimidazole-carbazole conjugates for the stabilization of human telomeric DNA, telomerase inhibition, and their selective action on cancer cells.
    Maji B; Kumar K; Kaulage M; Muniyappa K; Bhattacharya S
    J Med Chem; 2014 Aug; 57(16):6973-88. PubMed ID: 25062468
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dimeric 1,3-phenylene-bis(piperazinyl benzimidazole)s: synthesis and structure-activity investigations on their binding with human telomeric G-quadruplex DNA and telomerase inhibition properties.
    Jain AK; Paul A; Maji B; Muniyappa K; Bhattacharya S
    J Med Chem; 2012 Apr; 55(7):2981-93. PubMed ID: 22452380
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells.
    Zhou G; Liu X; Li Y; Xu S; Ma C; Wu X; Cheng Y; Yu Z; Zhao G; Chen Y
    Oncotarget; 2016 Mar; 7(12):14925-39. PubMed ID: 26908447
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational studies and solvent-accessible surface area analysis of known selective DNA G-Quadruplex binders.
    Alcaro S; Artese A; Costa G; Distinto S; Ortuso F; Parrotta L
    Biochimie; 2011 Aug; 93(8):1267-74. PubMed ID: 21699954
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Telomere inhibition and telomere disruption as processes for drug targeting.
    Rezler EM; Bearss DJ; Hurley LH
    Annu Rev Pharmacol Toxicol; 2003; 43():359-79. PubMed ID: 12540745
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New dimeric carbazole-benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer.
    Maji B; Kumar K; Muniyappa K; Bhattacharya S
    Org Biomol Chem; 2015 Aug; 13(30):8335-48. PubMed ID: 26149178
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of G-quadruplexes with nonintercalating duplex-DNA minor groove binding ligands.
    Jain AK; Bhattacharya S
    Bioconjug Chem; 2011 Dec; 22(12):2355-68. PubMed ID: 22074555
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An evaluation cascade for G-quadruplex telomere targeting agents in human cancer cells.
    Gunaratnam M; Neidle S
    Methods Mol Biol; 2010; 613():303-13. PubMed ID: 19997892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective interaction of ethidium derivatives with quadruplexes: an equilibrium dialysis and electrospray ionization mass spectrometry analysis.
    Rosu F; De Pauw E; Guittat L; Alberti P; Lacroix L; Mailliet P; Riou JF; Mergny JL
    Biochemistry; 2003 Sep; 42(35):10361-71. PubMed ID: 12950163
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human telomerase inhibition by regioisomeric disubstituted amidoanthracene-9,10-diones.
    Perry PJ; Reszka AP; Wood AA; Read MA; Gowan SM; Dosanjh HS; Trent JO; Jenkins TC; Kelland LR; Neidle S
    J Med Chem; 1998 Nov; 41(24):4873-84. PubMed ID: 9822556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.
    Brassart B; Gomez D; De Cian A; Paterski R; Montagnac A; Qui KH; Temime-Smaali N; Trentesaux C; Mergny JL; Gueritte F; Riou JF
    Mol Pharmacol; 2007 Sep; 72(3):631-40. PubMed ID: 17586599
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.