287 related articles for article (PubMed ID: 24697360)
1. Biased ligand modulation of seven transmembrane receptors (7TMRs): functional implications for drug discovery.
Correll CC; McKittrick BA
J Med Chem; 2014 Aug; 57(16):6887-96. PubMed ID: 24697360
[TBL] [Abstract][Full Text] [Related]
2. Beta-arrestin-biased ligands at seven-transmembrane receptors.
Violin JD; Lefkowitz RJ
Trends Pharmacol Sci; 2007 Aug; 28(8):416-22. PubMed ID: 17644195
[TBL] [Abstract][Full Text] [Related]
3. Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors.
Shukla AK; Violin JD; Whalen EJ; Gesty-Palmer D; Shenoy SK; Lefkowitz RJ
Proc Natl Acad Sci U S A; 2008 Jul; 105(29):9988-93. PubMed ID: 18621717
[TBL] [Abstract][Full Text] [Related]
4. Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors.
Reiter E; Ahn S; Shukla AK; Lefkowitz RJ
Annu Rev Pharmacol Toxicol; 2012; 52():179-97. PubMed ID: 21942629
[TBL] [Abstract][Full Text] [Related]
5. Distinct CCK-2 receptor conformations associated with β-arrestin-2 recruitment or phospholipase-C activation revealed by a biased antagonist.
Magnan R; Escrieut C; Gigoux V; De K; Clerc P; Niu F; Azema J; Masri B; Cordomi A; Baltas M; Tikhonova IG; Fourmy D
J Am Chem Soc; 2013 Feb; 135(7):2560-73. PubMed ID: 23323542
[TBL] [Abstract][Full Text] [Related]
6. Teaching old receptors new tricks: biasing seven-transmembrane receptors.
Rajagopal S; Rajagopal K; Lefkowitz RJ
Nat Rev Drug Discov; 2010 May; 9(5):373-86. PubMed ID: 20431569
[TBL] [Abstract][Full Text] [Related]
7. Measurements of β-arrestin recruitment to activated seven transmembrane receptors using enzyme complementation.
Bassoni DL; Raab WJ; Achacoso PL; Loh CY; Wehrman TS
Methods Mol Biol; 2012; 897():181-203. PubMed ID: 22674166
[TBL] [Abstract][Full Text] [Related]
8. beta-arrestin-biased agonism at the beta2-adrenergic receptor.
Drake MT; Violin JD; Whalen EJ; Wisler JW; Shenoy SK; Lefkowitz RJ
J Biol Chem; 2008 Feb; 283(9):5669-76. PubMed ID: 18086673
[TBL] [Abstract][Full Text] [Related]
9. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).
Xiao K; Sun J; Kim J; Rajagopal S; Zhai B; Villén J; Haas W; Kovacs JJ; Shukla AK; Hara MR; Hernandez M; Lachmann A; Zhao S; Lin Y; Cheng Y; Mizuno K; Ma'ayan A; Gygi SP; Lefkowitz RJ
Proc Natl Acad Sci U S A; 2010 Aug; 107(34):15299-304. PubMed ID: 20686112
[TBL] [Abstract][Full Text] [Related]
10. Elucidating structural and molecular mechanisms of β-arrestin-biased agonism at GPCRs via MS-based proteomics.
Xiao K; Sun J
Cell Signal; 2018 Jan; 41():56-64. PubMed ID: 28939107
[TBL] [Abstract][Full Text] [Related]
11. In vivo veritas, the next frontier for functionally selective GPCR ligands.
Beaulieu JM
Methods; 2016 Jan; 92():64-71. PubMed ID: 26320830
[TBL] [Abstract][Full Text] [Related]
12. Arrestins and protein ubiquitination.
Kommaddi RP; Shenoy SK
Prog Mol Biol Transl Sci; 2013; 118():175-204. PubMed ID: 23764054
[TBL] [Abstract][Full Text] [Related]
13. Beta-arrestin biased agonism/antagonism at cardiovascular seven transmembrane-spanning receptors.
Lymperopoulos A
Curr Pharm Des; 2012; 18(2):192-8. PubMed ID: 22229558
[TBL] [Abstract][Full Text] [Related]
14. β-Arrestin-mediated receptor trafficking and signal transduction.
Shenoy SK; Lefkowitz RJ
Trends Pharmacol Sci; 2011 Sep; 32(9):521-33. PubMed ID: 21680031
[TBL] [Abstract][Full Text] [Related]
15. Biased signalling: the instinctive skill of the cell in the selection of appropriate signalling pathways.
Liu Y; Yang Y; Ward R; An S; Guo XX; Li W; Xu TR
Biochem J; 2015 Sep; 470(2):155-67. PubMed ID: 26348905
[TBL] [Abstract][Full Text] [Related]
16. Molecular scaffolds regulate bidirectional crosstalk between Wnt and classical seven-transmembrane-domain receptor signaling pathways.
Force T; Woulfe K; Koch WJ; Kerkelä R
Sci STKE; 2007 Jul; 2007(397):pe41. PubMed ID: 17666710
[TBL] [Abstract][Full Text] [Related]
17. A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine.
DeWire SM; Yamashita DS; Rominger DH; Liu G; Cowan CL; Graczyk TM; Chen XT; Pitis PM; Gotchev D; Yuan C; Koblish M; Lark MW; Violin JD
J Pharmacol Exp Ther; 2013 Mar; 344(3):708-17. PubMed ID: 23300227
[TBL] [Abstract][Full Text] [Related]
18. Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.
Allen JA; Yost JM; Setola V; Chen X; Sassano MF; Chen M; Peterson S; Yadav PN; Huang XP; Feng B; Jensen NH; Che X; Bai X; Frye SV; Wetsel WC; Caron MG; Javitch JA; Roth BL; Jin J
Proc Natl Acad Sci U S A; 2011 Nov; 108(45):18488-93. PubMed ID: 22025698
[TBL] [Abstract][Full Text] [Related]
19. Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling.
Shukla AK; Xiao K; Lefkowitz RJ
Trends Biochem Sci; 2011 Sep; 36(9):457-69. PubMed ID: 21764321
[TBL] [Abstract][Full Text] [Related]
20. Synoptic pharmacology: Detecting and assessing the pharmacological significance of ligands for orphan receptors.
Kenakin TP
Pharmacol Res; 2016 Dec; 114():284-290. PubMed ID: 26804250
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]