BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

471 related articles for article (PubMed ID: 24705250)

  • 1. Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma.
    Fontebasso AM; Papillon-Cavanagh S; Schwartzentruber J; Nikbakht H; Gerges N; Fiset PO; Bechet D; Faury D; De Jay N; Ramkissoon LA; Corcoran A; Jones DT; Sturm D; Johann P; Tomita T; Goldman S; Nagib M; Bendel A; Goumnerova L; Bowers DC; Leonard JR; Rubin JB; Alden T; Browd S; Geyer JR; Leary S; Jallo G; Cohen K; Gupta N; Prados MD; Carret AS; Ellezam B; Crevier L; Klekner A; Bognar L; Hauser P; Garami M; Myseros J; Dong Z; Siegel PM; Malkin H; Ligon AH; Albrecht S; Pfister SM; Ligon KL; Majewski J; Jabado N; Kieran MW
    Nat Genet; 2014 May; 46(5):462-6. PubMed ID: 24705250
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.
    Buczkowicz P; Hoeman C; Rakopoulos P; Pajovic S; Letourneau L; Dzamba M; Morrison A; Lewis P; Bouffet E; Bartels U; Zuccaro J; Agnihotri S; Ryall S; Barszczyk M; Chornenkyy Y; Bourgey M; Bourque G; Montpetit A; Cordero F; Castelo-Branco P; Mangerel J; Tabori U; Ho KC; Huang A; Taylor KR; Mackay A; Bendel AE; Nazarian J; Fangusaro JR; Karajannis MA; Zagzag D; Foreman NK; Donson A; Hegert JV; Smith A; Chan J; Lafay-Cousin L; Dunn S; Hukin J; Dunham C; Scheinemann K; Michaud J; Zelcer S; Ramsay D; Cain J; Brennan C; Souweidane MM; Jones C; Allis CD; Brudno M; Becher O; Hawkins C
    Nat Genet; 2014 May; 46(5):451-6. PubMed ID: 24705254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ACVR1 mutations and the genomic landscape of pediatric diffuse glioma.
    Zadeh G; Aldape K
    Nat Genet; 2014 May; 46(5):421-2. PubMed ID: 24769718
    [No Abstract]   [Full Text] [Related]  

  • 4. Genetics: ACVR1 mutations-a key piece in paediatric diffuse glioma.
    Villanueva MT
    Nat Rev Clin Oncol; 2014 Jun; 11(6):300. PubMed ID: 24840074
    [No Abstract]   [Full Text] [Related]  

  • 5. Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas.
    Bechet D; Gielen GG; Korshunov A; Pfister SM; Rousso C; Faury D; Fiset PO; Benlimane N; Lewis PW; Lu C; David Allis C; Kieran MW; Ligon KL; Pietsch T; Ellezam B; Albrecht S; Jabado N
    Acta Neuropathol; 2014 Nov; 128(5):733-41. PubMed ID: 25200321
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
    Hoeman CM; Cordero FJ; Hu G; Misuraca K; Romero MM; Cardona HJ; Nazarian J; Hashizume R; McLendon R; Yu P; Procissi D; Gadd S; Becher OJ
    Nat Commun; 2019 Mar; 10(1):1023. PubMed ID: 30833574
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma.
    Taylor KR; Mackay A; Truffaux N; Butterfield Y; Morozova O; Philippe C; Castel D; Grasso CS; Vinci M; Carvalho D; Carcaboso AM; de Torres C; Cruz O; Mora J; Entz-Werle N; Ingram WJ; Monje M; Hargrave D; Bullock AN; Puget S; Yip S; Jones C; Grill J
    Nat Genet; 2014 May; 46(5):457-461. PubMed ID: 24705252
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
    Fortin J; Tian R; Zarrabi I; Hill G; Williams E; Sanchez-Duffhues G; Thorikay M; Ramachandran P; Siddaway R; Wong JF; Wu A; Apuzzo LN; Haight J; You-Ten A; Snow BE; Wakeham A; Goldhamer DJ; Schramek D; Bullock AN; Dijke PT; Hawkins C; Mak TW
    Cancer Cell; 2020 Mar; 37(3):308-323.e12. PubMed ID: 32142668
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway.
    Omi M; Kaartinen V; Mishina Y
    J Biol Chem; 2019 Nov; 294(47):17818-17836. PubMed ID: 31619522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development.
    Pan H; Zhang H; Abraham P; Komatsu Y; Lyons K; Kaartinen V; Mishina Y
    Dev Biol; 2017 Sep; 429(1):260-270. PubMed ID: 28641928
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.
    Wu G; Broniscer A; McEachron TA; Lu C; Paugh BS; Becksfort J; Qu C; Ding L; Huether R; Parker M; Zhang J; Gajjar A; Dyer MA; Mullighan CG; Gilbertson RJ; Mardis ER; Wilson RK; Downing JR; Ellison DW; Zhang J; Baker SJ;
    Nat Genet; 2012 Jan; 44(3):251-3. PubMed ID: 22286216
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.
    Reinhardt A; Stichel D; Schrimpf D; Sahm F; Korshunov A; Reuss DE; Koelsche C; Huang K; Wefers AK; Hovestadt V; Sill M; Gramatzki D; Felsberg J; Reifenberger G; Koch A; Thomale UW; Becker A; Hans VH; Prinz M; Staszewski O; Acker T; Dohmen H; Hartmann C; Mueller W; Tuffaha MSA; Paulus W; Heß K; Brokinkel B; Schittenhelm J; Monoranu CM; Kessler AF; Loehr M; Buslei R; Deckert M; Mawrin C; Kohlhof P; Hewer E; Olar A; Rodriguez FJ; Giannini C; NageswaraRao AA; Tabori U; Nunes NM; Weller M; Pohl U; Jaunmuktane Z; Brandner S; Unterberg A; Hänggi D; Platten M; Pfister SM; Wick W; Herold-Mende C; Jones DTW; von Deimling A; Capper D
    Acta Neuropathol; 2018 Aug; 136(2):273-291. PubMed ID: 29564591
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Variant BMP receptor mutations causing fibrodysplasia ossificans progressiva (FOP) in humans show BMP ligand-independent receptor activation in zebrafish.
    Mucha BE; Hashiguchi M; Zinski J; Shore EM; Mullins MC
    Bone; 2018 Apr; 109():225-231. PubMed ID: 29307777
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Low-Grade Gemistocytic Morphology in H3 G34R-Mutant Gliomas and Concurrent K27M Mutation: Clinicopathologic Findings.
    Morris M; Driscoll M; Henson JW; Cobbs C; Jiang L; Gocke CD; Chen L; Rodriguez FJ
    J Neuropathol Exp Neurol; 2020 Oct; 79(10):1038-1043. PubMed ID: 32954438
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Fibrodysplasia Ossificans Progressiva (FOP) mutation p.R206H in ACVR1 confers an altered ligand response.
    Hildebrand L; Stange K; Deichsel A; Gossen M; Seemann P
    Cell Signal; 2017 Jan; 29():23-30. PubMed ID: 27713089
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization.
    Shen Q; Little SC; Xu M; Haupt J; Ast C; Katagiri T; Mundlos S; Seemann P; Kaplan FS; Mullins MC; Shore EM
    J Clin Invest; 2009 Nov; 119(11):3462-72. PubMed ID: 19855136
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers.
    Korshunov A; Ryzhova M; Hovestadt V; Bender S; Sturm D; Capper D; Meyer J; Schrimpf D; Kool M; Northcott PA; Zheludkova O; Milde T; Witt O; Kulozik AE; Reifenberger G; Jabado N; Perry A; Lichter P; von Deimling A; Pfister SM; Jones DT
    Acta Neuropathol; 2015 May; 129(5):669-78. PubMed ID: 25752754
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
    Jones DT; Hutter B; Jäger N; Korshunov A; Kool M; Warnatz HJ; Zichner T; Lambert SR; Ryzhova M; Quang DA; Fontebasso AM; Stütz AM; Hutter S; Zuckermann M; Sturm D; Gronych J; Lasitschka B; Schmidt S; Seker-Cin H; Witt H; Sultan M; Ralser M; Northcott PA; Hovestadt V; Bender S; Pfaff E; Stark S; Faury D; Schwartzentruber J; Majewski J; Weber UD; Zapatka M; Raeder B; Schlesner M; Worth CL; Bartholomae CC; von Kalle C; Imbusch CD; Radomski S; Lawerenz C; van Sluis P; Koster J; Volckmann R; Versteeg R; Lehrach H; Monoranu C; Winkler B; Unterberg A; Herold-Mende C; Milde T; Kulozik AE; Ebinger M; Schuhmann MU; Cho YJ; Pomeroy SL; von Deimling A; Witt O; Taylor MD; Wolf S; Karajannis MA; Eberhart CG; Scheurlen W; Hasselblatt M; Ligon KL; Kieran MW; Korbel JO; Yaspo ML; Brors B; Felsberg J; Reifenberger G; Collins VP; Jabado N; Eils R; Lichter P; Pfister SM;
    Nat Genet; 2013 Aug; 45(8):927-32. PubMed ID: 23817572
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Diffuse Midline Gliomas with Histone H3-K27M Mutation: A Series of 47 Cases Assessing the Spectrum of Morphologic Variation and Associated Genetic Alterations.
    Solomon DA; Wood MD; Tihan T; Bollen AW; Gupta N; Phillips JJ; Perry A
    Brain Pathol; 2016 Sep; 26(5):569-80. PubMed ID: 26517431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.
    Salloum R; McConechy MK; Mikael LG; Fuller C; Drissi R; DeWire M; Nikbakht H; De Jay N; Yang X; Boue D; Chow LML; Finlay JL; Gayden T; Karamchandani J; Hummel TR; Olshefski R; Osorio DS; Stevenson C; Kleinman CL; Majewski J; Fouladi M; Jabado N
    Acta Neuropathol Commun; 2017 Oct; 5(1):78. PubMed ID: 29084603
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.