231 related articles for article (PubMed ID: 24706823)
1. Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors.
Tessem JS; Moss LG; Chao LC; Arlotto M; Lu D; Jensen MV; Stephens SB; Tontonoz P; Hohmeier HE; Newgard CB
Proc Natl Acad Sci U S A; 2014 Apr; 111(14):5242-7. PubMed ID: 24706823
[TBL] [Abstract][Full Text] [Related]
2. Aurora Kinase A is critical for the Nkx6.1 mediated β-cell proliferation pathway.
Hobson A; Draney C; Stratford A; Becker TC; Lu D; Arlotto M; Tessem JS
Islets; 2015; 7(1):e1027854. PubMed ID: 26030060
[TBL] [Abstract][Full Text] [Related]
3. Cdk5r1 Overexpression Induces Primary β-Cell Proliferation.
Draney C; Hobson AE; Grover SG; Jack BO; Tessem JS
J Diabetes Res; 2016; 2016():6375804. PubMed ID: 26788519
[TBL] [Abstract][Full Text] [Related]
4. Nkx6.1-mediated insulin secretion and β-cell proliferation is dependent on upregulation of c-Fos.
Ray JD; Kener KB; Bitner BF; Wright BJ; Ballard MS; Barrett EJ; Hill JT; Moss LG; Tessem JS
FEBS Lett; 2016 Jun; 590(12):1791-803. PubMed ID: 27164028
[TBL] [Abstract][Full Text] [Related]
5. β-Cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion.
Reynolds MS; Hancock CR; Ray JD; Kener KB; Draney C; Garland K; Hardman J; Bikman BT; Tessem JS
Am J Physiol Endocrinol Metab; 2016 Jul; 311(1):E186-201. PubMed ID: 27221116
[TBL] [Abstract][Full Text] [Related]
6. Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1.
Schisler JC; Fueger PT; Babu DA; Hohmeier HE; Tessem JS; Lu D; Becker TC; Naziruddin B; Levy M; Mirmira RG; Newgard CB
Mol Cell Biol; 2008 May; 28(10):3465-76. PubMed ID: 18347054
[TBL] [Abstract][Full Text] [Related]
7. Role of local muscle contractile activity in the exercise-induced increase in NR4A receptor mRNA expression.
Kawasaki E; Hokari F; Sasaki M; Sakai A; Koshinaka K; Kawanaka K
J Appl Physiol (1985); 2009 Jun; 106(6):1826-31. PubMed ID: 19359610
[TBL] [Abstract][Full Text] [Related]
8. The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells.
Schisler JC; Jensen PB; Taylor DG; Becker TC; Knop FK; Takekawa S; German M; Weir GC; Lu D; Mirmira RG; Newgard CB
Proc Natl Acad Sci U S A; 2005 May; 102(20):7297-302. PubMed ID: 15883383
[TBL] [Abstract][Full Text] [Related]
9. The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass.
Close AF; Dadheech N; Villela BS; Rouillard C; Buteau J
J Biol Chem; 2019 Mar; 294(13):4889-4897. PubMed ID: 30696767
[TBL] [Abstract][Full Text] [Related]
10. Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2.
Hayes HL; Moss LG; Schisler JC; Haldeman JM; Zhang Z; Rosenberg PB; Newgard CB; Hohmeier HE
Mol Cell Biol; 2013 Oct; 33(20):4017-29. PubMed ID: 23938296
[TBL] [Abstract][Full Text] [Related]
11. MiR-190b impedes pancreatic β cell proliferation and insulin secretion by targeting NKX6-1 and may associate to gestational diabetes mellitus.
Wang S; Wei D; Sun X; Li Y; Li D; Chen B
J Recept Signal Transduct Res; 2021 Aug; 41(4):349-356. PubMed ID: 32862769
[TBL] [Abstract][Full Text] [Related]
12. NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas.
Henseleit KD; Nelson SB; Kuhlbrodt K; Hennings JC; Ericson J; Sander M
Development; 2005 Jul; 132(13):3139-49. PubMed ID: 15944193
[TBL] [Abstract][Full Text] [Related]
13. The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.
Wenzl K; Troppan K; Neumeister P; Deutsch AJ
Curr Drug Targets; 2015; 16(1):38-46. PubMed ID: 25410408
[TBL] [Abstract][Full Text] [Related]
14. CEBPA Overexpression Enhances β-Cell Proliferation and Survival.
Ellsworth PN; Herring JA; Leifer AH; Ray JD; Elison WS; Poulson PD; Crabtree JE; Van Ry PM; Tessem JS
Biology (Basel); 2024 Feb; 13(2):. PubMed ID: 38392328
[TBL] [Abstract][Full Text] [Related]
15. NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling.
Freire PR; Conneely OM
Blood; 2018 Mar; 131(10):1081-1093. PubMed ID: 29343483
[TBL] [Abstract][Full Text] [Related]
16. Distinct regulation of hepatic nuclear factor 1alpha by NKX6.1 in pancreatic beta cells.
Donelan W; Koya V; Li SW; Yang LJ
J Biol Chem; 2010 Apr; 285(16):12181-9. PubMed ID: 20106981
[TBL] [Abstract][Full Text] [Related]
17. Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance.
Schaffer AE; Yang AJ; Thorel F; Herrera PL; Sander M
Mol Endocrinol; 2011 Nov; 25(11):1904-14. PubMed ID: 21964593
[TBL] [Abstract][Full Text] [Related]
18. The transcriptional repressor Nkx6.1 also functions as a deoxyribonucleic acid context-dependent transcriptional activator during pancreatic beta-cell differentiation: evidence for feedback activation of the nkx6.1 gene by Nkx6.1.
Iype T; Taylor DG; Ziesmann SM; Garmey JC; Watada H; Mirmira RG
Mol Endocrinol; 2004 Jun; 18(6):1363-75. PubMed ID: 15056733
[TBL] [Abstract][Full Text] [Related]
19. Deficiency of transcription factor Nkx6.1 does not prevent insulin secretion in INS-1E cells.
Pavluch V; Engstová H; Špačková J; Ježek P
Sci Rep; 2023 Jan; 13(1):683. PubMed ID: 36639413
[TBL] [Abstract][Full Text] [Related]
20. HDAC1 overexpression enhances β-cell proliferation by down-regulating Cdkn1b/p27.
Draney C; Austin MC; Leifer AH; Smith CJ; Kener KB; Aitken TJ; Hess KH; Haines AC; Lett E; Hernandez-Carretero A; Fueger PT; Arlotto M; Tessem JS
Biochem J; 2018 Dec; 475(24):3997-4010. PubMed ID: 30322885
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]