These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 2470749)

  • 1. Methenyltetrahydrofolate synthetase prevents the inhibition of phosphoribosyl 5-aminoimidazole 4-carboxamide ribonucleotide formyltransferase by 5-formyltetrahydrofolate polyglutamates.
    Bertrand R; Jolivet J
    J Biol Chem; 1989 May; 264(15):8843-6. PubMed ID: 2470749
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide.
    Baggott JE; Vaughn WH; Hudson BB
    Biochem J; 1986 May; 236(1):193-200. PubMed ID: 2431676
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.
    Allegra CJ; Hoang K; Yeh GC; Drake JC; Baram J
    J Biol Chem; 1987 Oct; 262(28):13520-6. PubMed ID: 2443493
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
    Shih C; Chen VJ; Gossett LS; Gates SB; MacKellar WC; Habeck LL; Shackelford KA; Mendelsohn LG; Soose DJ; Patel VF; Andis SL; Bewley JR; Rayl EA; Moroson BA; Beardsley GP; Kohler W; Ratnam M; Schultz RM
    Cancer Res; 1997 Mar; 57(6):1116-23. PubMed ID: 9067281
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.
    Allegra CJ; Drake JC; Jolivet J; Chabner BA
    Proc Natl Acad Sci U S A; 1985 Aug; 82(15):4881-5. PubMed ID: 3860829
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human liver methenyltetrahydrofolate synthetase: improved purification and increased affinity for folate polyglutamate substrates.
    Bertrand R; MacKenzie RE; Jolivet J
    Biochim Biophys Acta; 1987 Jan; 911(2):154-61. PubMed ID: 3801490
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and biochemical properties of 10-formyldihydrofolate, a novel folate found in methotrexate-treated cells.
    Baram J; Chabner BA; Drake JC; Fitzhugh AL; Sholar PW; Allegra CJ
    J Biol Chem; 1988 May; 263(15):7105-11. PubMed ID: 3366769
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of glycinamide ribonucleotide formyltransferase and other folate enzymes by homofolate polyglutamates in human lymphoma and murine leukemia cell extracts.
    Thorndike J; Gaumont Y; Kisliuk RL; Sirotnak FM; Murthy BR; Nair MG; Piper JR
    Cancer Res; 1989 Jan; 49(1):158-63. PubMed ID: 2521177
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A; Galivan J; Beardsley GP; Bader H; O'Connor BM; Russello O; Moroson BA; DeYarman MT; Kerwar SS; Freisheim JH
    Cancer Res; 1992 Apr; 52(8):2148-55. PubMed ID: 1313737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cofactor role for 10-formyldihydrofolic acid.
    Baggott JE; Johanning GL; Branham KE; Prince CW; Morgan SL; Eto I; Vaughn WH
    Biochem J; 1995 Jun; 308 ( Pt 3)(Pt 3):1031-6. PubMed ID: 8948466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence that the folate-requiring enzymes of de novo purine biosynthesis are encoded by individual mRNAs.
    Wasserman GF; Mueller WT; Benkovic SJ; Liao WS; Taylor J
    Biochemistry; 1984 Dec; 23(26):6704-10. PubMed ID: 6335666
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of chicken liver 5-aminoimidazole-4-carboxamide ribonucleotide transformylase by 5,8-dideaza analogues of folic acid.
    Mueller WT; Smith GK; Benkovic SJ; Hynes JB
    Biochem Pharmacol; 1988 Feb; 37(3):449-51. PubMed ID: 3337744
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of 5,11-methenyltetrahydrohomofolate and its antifolate activity in vitro.
    Caperelli CA; Domanico P; Benkovic SJ
    J Med Chem; 1981 Sep; 24(9):1086-8. PubMed ID: 7288824
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antifolates induce primary inhibition of the de novo purine pathway prior to 5-aminoimidazole-4-carboxamide ribotide transformylase in leukemia cells.
    Lyons SD; Christopherson RI
    Biochem Int; 1991 May; 24(1):187-97. PubMed ID: 1768258
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A multifunctional protein possessing glycinamide ribonucleotide synthetase, glycinamide ribonucleotide transformylase, and aminoimidazole ribonucleotide synthetase activities in de novo purine biosynthesis.
    Daubner SC; Schrimsher JL; Schendel FJ; Young M; Henikoff S; Patterson D; Stubbe J; Benkovic SJ
    Biochemistry; 1985 Dec; 24(25):7059-62. PubMed ID: 4084560
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of HKSV28 cell growth by 5,11-methenyl-tetrahydrohomofolate.
    Slieker LJ; Benkovic SJ
    Mol Pharmacol; 1984 Mar; 25(2):294-302. PubMed ID: 6700575
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mammalian glycinamide ribonucleotide transformylase. Kinetic mechanism and associated de novo purine biosynthetic activities.
    Caperelli CA
    J Biol Chem; 1989 Mar; 264(9):5053-7. PubMed ID: 2925682
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tight binding of folate substrates and inhibitors to recombinant mouse glycinamide ribonucleotide formyltransferase.
    Sanghani SP; Moran RG
    Biochemistry; 1997 Aug; 36(34):10506-16. PubMed ID: 9265631
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathway.
    Desharnais J; Hwang I; Zhang Y; Tavassoli A; Baboval J; Benkovic SJ; Wilson IA; Boger DL
    Bioorg Med Chem; 2003 Oct; 11(20):4511-21. PubMed ID: 13129587
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nucleotide sequence analysis of genes purH and purD involved in the de novo purine nucleotide biosynthesis of Escherichia coli.
    Aiba A; Mizobuchi K
    J Biol Chem; 1989 Dec; 264(35):21239-46. PubMed ID: 2687276
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.