BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 24711418)

  • 1. Distinct phosphatases antagonize the p53 response in different phases of the cell cycle.
    Shaltiel IA; Aprelia M; Saurin AT; Chowdhury D; Kops GJ; Voest EE; Medema RH
    Proc Natl Acad Sci U S A; 2014 May; 111(20):7313-8. PubMed ID: 24711418
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
    Yoda A; Toyoshima K; Watanabe Y; Onishi N; Hazaka Y; Tsukuda Y; Tsukada J; Kondo T; Tanaka Y; Minami Y
    J Biol Chem; 2008 Jul; 283(27):18969-79. PubMed ID: 18482988
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression.
    Lindqvist A; de Bruijn M; Macurek L; Brás A; Mensinga A; Bruinsma W; Voets O; Kranenburg O; Medema RH
    EMBO J; 2009 Oct; 28(20):3196-206. PubMed ID: 19713933
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint.
    Kleiblova P; Shaltiel IA; Benada J; Ševčík J; Pecháčková S; Pohlreich P; Voest EE; Dundr P; Bartek J; Kleibl Z; Medema RH; Macurek L
    J Cell Biol; 2013 May; 201(4):511-21. PubMed ID: 23649806
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.
    Lu X; Nguyen TA; Donehower LA
    Cell Cycle; 2005 Aug; 4(8):1060-4. PubMed ID: 15970689
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dissociation between cell cycle arrest and apoptosis can occur in Li-Fraumeni cells heterozygous for p53 gene mutations.
    Delia D; Goi K; Mizutani S; Yamada T; Aiello A; Fontanella E; Lamorte G; Iwata S; Ishioka C; Krajewski S; Reed JC; Pierotti MA
    Oncogene; 1997 May; 14(18):2137-47. PubMed ID: 9174049
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human papillomavirus E6 and E7 oncoproteins alter cell cycle progression but not radiosensitivity of carcinoma cells treated with low-dose-rate radiation.
    DeWeese TL; Walsh JC; Dillehay LE; Kessis TD; Hedrick L; Cho KR; Nelson WG
    Int J Radiat Oncol Biol Phys; 1997 Jan; 37(1):145-54. PubMed ID: 9054890
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.
    Brazina J; Svadlenka J; Macurek L; Andera L; Hodny Z; Bartek J; Hanzlikova H
    Cell Cycle; 2015; 14(3):375-87. PubMed ID: 25659035
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Cell cycle regulation after exposure to ionizing radiation].
    Teyssier F; Bay JO; Dionet C; Verrelle P
    Bull Cancer; 1999 Apr; 86(4):345-57. PubMed ID: 10341340
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase.
    Müllers E; Silva Cascales H; Jaiswal H; Saurin AT; Lindqvist A
    Cell Cycle; 2014; 13(17):2733-43. PubMed ID: 25486360
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.
    Zimmermann M; Arachchige-Don AS; Donaldson MS; Dallapiazza RF; Cowan CE; Horne MC
    J Biol Chem; 2012 Jun; 287(27):22838-53. PubMed ID: 22589537
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Complexity of the mechanisms of initiation and maintenance of DNA damage-induced G2-phase arrest and subsequent G1-phase arrest: TP53-dependent and TP53-independent roles.
    DeSimone JN; Bengtsson U; Wang X; Lao XY; Redpath JL; Stanbridge EJ
    Radiat Res; 2003 Jan; 159(1):72-85. PubMed ID: 12492370
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel assay for screening WIP1 phosphatase substrates in nuclear extracts.
    Storchova R; Burdova K; Palek M; Medema RH; Macurek L
    FEBS J; 2021 Oct; 288(20):6035-6051. PubMed ID: 33982878
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Down-regulation of wild-type p53-induced phosphatase 1 (Wip1) plays a critical role in regulating several p53-dependent functions in premature senescent tumor cells.
    Crescenzi E; Raia Z; Pacifico F; Mellone S; Moscato F; Palumbo G; Leonardi A
    J Biol Chem; 2013 Jun; 288(23):16212-16224. PubMed ID: 23612976
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation.
    Schito ML; Demidov ON; Saito S; Ashwell JD; Appella E
    J Immunol; 2006 Apr; 176(8):4818-25. PubMed ID: 16585576
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of Wip1 sensitizes cells to stress- and DNA damage-induced apoptosis.
    Xia Y; Ongusaha P; Lee SW; Liou YC
    J Biol Chem; 2009 Jun; 284(26):17428-37. PubMed ID: 19395378
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The estrogen receptor alpha pathway induces oncogenic Wip1 phosphatase gene expression.
    Han HS; Yu E; Song JY; Park JY; Jang SJ; Choi J
    Mol Cancer Res; 2009 May; 7(5):713-23. PubMed ID: 19435816
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases.
    Yamaguchi H; Durell SR; Chatterjee DK; Anderson CW; Appella E
    Biochemistry; 2007 Nov; 46(44):12594-603. PubMed ID: 17939684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.
    Xie G; Habbersett RC; Jia Y; Peterson SR; Lehnert BE; Bradbury EM; D'Anna JA
    Oncogene; 1998 Feb; 16(6):721-36. PubMed ID: 9488036
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.