BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

267 related articles for article (PubMed ID: 24711448)

  • 1. Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing.
    Song D; Li LS; Arsenault PR; Tan Q; Bigham AW; Heaton-Johnson KJ; Master SR; Lee FS
    J Biol Chem; 2014 May; 289(21):14656-65. PubMed ID: 24711448
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tibetan
    Song D; Navalsky BE; Guan W; Ingersoll C; Wang T; Loro E; Eeles L; Matchett KB; Percy MJ; Walsby-Tickle J; McCullagh JSO; Medina RJ; Khurana TS; Bigham AW; Lappin TR; Lee FS
    Proc Natl Acad Sci U S A; 2020 Jun; 117(22):12230-12238. PubMed ID: 32414920
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The ribosomal chaperone NACA recruits PHD2 to cotranslationally modify HIF-α.
    Song D; Peng K; Palmer BE; Lee FS
    EMBO J; 2022 Nov; 41(22):e112059. PubMed ID: 36219563
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2α) polymorphism lowers hemoglobin concentration in Tibetan highlanders.
    Tashi T; Scott Reading N; Wuren T; Zhang X; Moore LG; Hu H; Tang F; Shestakova A; Lorenzo F; Burjanivova T; Koul P; Guchhait P; Wittwer CT; Julian CG; Shah B; Huff CD; Gordeuk VR; Prchal JT; Ge R
    J Mol Med (Berl); 2017 Jun; 95(6):665-670. PubMed ID: 28233034
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gain-of-function Tibetan PHD2
    Bhattacharya S; Shrimali NM; Mohammad G; Koul PA; Prchal JT; Guchhait P
    EBioMedicine; 2021 Jun; 68():103418. PubMed ID: 34102396
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of Small-Molecule PHD2 Zinc Finger Inhibitors that Activate Hypoxia Inducible Factor.
    Arsenault PR; Song D; Bergkamp M; Ravaschiere AM; Navalsky BE; Lieberman PM; Lee FS
    Chembiochem; 2016 Dec; 17(24):2316-2323. PubMed ID: 27770548
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prolyl hydroxylase domain protein 2 (PHD2) binds a Pro-Xaa-Leu-Glu motif, linking it to the heat shock protein 90 pathway.
    Song D; Li LS; Heaton-Johnson KJ; Arsenault PR; Master SR; Lee FS
    J Biol Chem; 2013 Apr; 288(14):9662-9674. PubMed ID: 23413029
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.
    Arsenault PR; Song D; Chung YJ; Khurana TS; Lee FS
    Mol Cell Biol; 2016 Sep; 36(18):2328-43. PubMed ID: 27325674
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer.
    Lanikova L; Reading NS; Hu H; Tashi T; Burjanivova T; Shestakova A; Siwakoti B; Thakur BK; Pun CB; Sapkota A; Abdelaziz S; Feng BJ; Huff CD; Hashibe M; Prchal JT
    Oncotarget; 2017 Feb; 8(7):11739-11747. PubMed ID: 28036300
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An Erythrocytosis-Associated Mutation in the Zinc Finger of PHD2 Provides Insights into Its Binding of p23.
    Song D; Guan W; Coon LM; Al-Kali A; Oliveira JL; Lee FS
    Hypoxia (Auckl); 2019; 7():81-86. PubMed ID: 31853455
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic and immune changes in Tibetan high-altitude populations contribute to biological adaptation to hypoxia.
    Bai J; Li L; Li Y; Zhang L
    Environ Health Prev Med; 2022; 27():39. PubMed ID: 36244759
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human high-altitude adaptation: forward genetics meets the HIF pathway.
    Bigham AW; Lee FS
    Genes Dev; 2014 Oct; 28(20):2189-204. PubMed ID: 25319824
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation.
    Xiang K; Ouzhuluobu ; Peng Y; Yang Z; Zhang X; Cui C; Zhang H; Li M; Zhang Y; Bianba ; Gonggalanzi ; Basang ; Ciwangsangbu ; Wu T; Chen H; Shi H; Qi X; Su B
    Mol Biol Evol; 2013 Aug; 30(8):1889-98. PubMed ID: 23666208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic variants at the EGLN1 locus associated with high-altitude adaptation in Tibetans are absent or found at low frequency in highland Andeans.
    Heinrich EC; Wu L; Lawrence ES; Cole AM; Anza-Ramirez C; Villafuerte FC; Simonson TS
    Ann Hum Genet; 2019 May; 83(3):171-176. PubMed ID: 30719713
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.
    Tarhonskaya H; Hardy AP; Howe EA; Loik ND; Kramer HB; McCullagh JS; Schofield CJ; Flashman E
    J Biol Chem; 2015 Aug; 290(32):19726-42. PubMed ID: 26112411
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data.
    Bigham A; Bauchet M; Pinto D; Mao X; Akey JM; Mei R; Scherer SW; Julian CG; Wilson MJ; López Herráez D; Brutsaert T; Parra EJ; Moore LG; Shriver MD
    PLoS Genet; 2010 Sep; 6(9):e1001116. PubMed ID: 20838600
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypoxia Inducible Factor pathway proteins in high-altitude mammals.
    Trends Biochem Sci; ; . PubMed ID: 38036336
    [TBL] [Abstract][Full Text] [Related]  

  • 18.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 14.