BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 24712547)

  • 1. Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6.
    Bobby R; Robustelli P; Kralicek AV; Mobli M; King GF; Grötzinger J; Dingley AJ
    FEBS J; 2014 May; 281(10):2471-83. PubMed ID: 24712547
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex.
    Lacroix M; Rousseau F; Guilhot F; Malinge P; Magistrelli G; Herren S; Jones SA; Jones GW; Scheller J; Lissilaa R; Kosco-Vilbois M; Johnson Z; Buatois V; Ferlin W
    J Biol Chem; 2015 Nov; 290(45):26943-26953. PubMed ID: 26363066
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conservation of functional sites on interleukin-6 and implications for evolution of signaling complex assembly and therapeutic intervention.
    Veverka V; Baker T; Redpath NT; Carrington B; Muskett FW; Taylor RJ; Lawson AD; Henry AJ; Carr MD
    J Biol Chem; 2012 Nov; 287(47):40043-50. PubMed ID: 23027872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of the signal transducer glycoprotein 130 by both IL-6 and IL-11 requires two distinct binding epitopes.
    Kurth I; Horsten U; Pflanz S; Dahmen H; Küster A; Grötzinger J; Heinrich PC; Müller-Newen G
    J Immunol; 1999 Feb; 162(3):1480-7. PubMed ID: 9973404
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Dynamics Simulations Reveal Key Roles of the Interleukin-6 Alpha Receptor in the Assembly of the Human Interleukin-6 Receptor Complex.
    Schillinger O; Panwalkar V; Strodel B; Dingley AJ
    J Phys Chem B; 2017 Aug; 121(34):8113-8122. PubMed ID: 28783950
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The N-terminus of gp130 is critical for the formation of the high-affinity interleukin-6 receptor complex.
    Moritz RL; Ward LD; Tu GF; Fabri LJ; Ji H; Yasukawa K; Simpson RJ
    Growth Factors; 1999; 16(4):265-78. PubMed ID: 10427501
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor.
    Skiniotis G; Boulanger MJ; Garcia KC; Walz T
    Nat Struct Mol Biol; 2005 Jun; 12(6):545-51. PubMed ID: 15895091
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modular organization of Interleukin-6 and Interleukin-11 α-receptors.
    Nitz R; Lokau J; Aparicio-Siegmund S; Scheller J; Garbers C
    Biochimie; 2015 Dec; 119():175-82. PubMed ID: 26551279
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus.
    Aoki Y; Narazaki M; Kishimoto T; Tosato G
    Blood; 2001 Nov; 98(10):3042-9. PubMed ID: 11698289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reversal of some viral IL-6 electrostatic properties compared to IL-6 contributes to a loss of alpha receptor component recruitment.
    Perret D; Rousseau F; Tran V; Gascan H
    Proteins; 2005 Jul; 60(1):14-26. PubMed ID: 15861391
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex.
    Boulanger MJ; Chow DC; Brevnova EE; Garcia KC
    Science; 2003 Jun; 300(5628):2101-4. PubMed ID: 12829785
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The solution structure of the membrane-proximal cytokine receptor domain of the human interleukin-6 receptor.
    Hecht O; Dingley AJ; Schwanter A; Ozbek S; Rose-John S; Grötzinger J
    Biol Chem; 2006 Sep; 387(9):1255-9. PubMed ID: 16972794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural requirements for gp80 independence of human herpesvirus 8 interleukin-6 (vIL-6) and evidence for gp80 stabilization of gp130 signaling complexes induced by vIL-6.
    Chen D; Nicholas J
    J Virol; 2006 Oct; 80(19):9811-21. PubMed ID: 16973585
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of the leukemia inhibitory factor receptor functional domains by chimeric receptors and cytokines.
    Aasland D; Schuster B; Grötzinger J; Rose-John S; Kallen KJ
    Biochemistry; 2003 May; 42(18):5244-52. PubMed ID: 12731865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of an extracellular gp130 cytokine receptor signaling complex.
    Chow D; He X; Snow AL; Rose-John S; Garcia KC
    Science; 2001 Mar; 291(5511):2150-5. PubMed ID: 11251120
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130.
    Chow D; Ho J; Nguyen Pham TL; Rose-John S; Garcia KC
    Biochemistry; 2001 Jun; 40(25):7593-603. PubMed ID: 11412113
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular dynamics analysis of the binding of human interleukin-6 with interleukin-6 α-receptor.
    Gupta M; Ha K; Agarwal R; Quarles LD; Smith JC
    Proteins; 2021 Feb; 89(2):163-173. PubMed ID: 32881084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Direct determination of the interleukin-6 binding epitope of the interleukin-6 receptor by NMR spectroscopy.
    Schwantner A; Dingley AJ; Ozbek S; Rose-John S; Grötzinger J
    J Biol Chem; 2004 Jan; 279(1):571-6. PubMed ID: 14557255
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Theoretical investigation of IL-6 multiprotein receptor assembly.
    Menziani MC; Fanelli F; De Benedetti PG
    Proteins; 1997 Dec; 29(4):528-44. PubMed ID: 9408949
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of the mechanism of action of anti-human interleukin-6 and anti-human interleukin-6 receptor-neutralising monoclonal antibodies.
    Kalai M; Montero-Julian FA; Brakenhoff JP; Fontaine V; De Wit L; Wollmer A; Brailly H; Content J; Grötzinger J
    Eur J Biochem; 1997 Nov; 249(3):690-700. PubMed ID: 9395315
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.