These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 24712655)

  • 1. Nuclear import of SAMHD1 is mediated by a classical karyopherin α/β1 dependent pathway and confers sensitivity to VpxMAC induced ubiquitination and proteasomal degradation.
    Schaller T; Pollpeter D; Apolonia L; Goujon C; Malim MH
    Retrovirology; 2014 Apr; 11():29. PubMed ID: 24712655
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradation.
    Guo H; Wei W; Wei Z; Liu X; Evans SL; Yang W; Wang H; Guo Y; Zhao K; Zhou JY; Yu XF
    PLoS One; 2013; 8(7):e66201. PubMed ID: 23874389
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus.
    Hofmann H; Logue EC; Bloch N; Daddacha W; Polsky SB; Schultz ML; Kim B; Landau NR
    J Virol; 2012 Dec; 86(23):12552-60. PubMed ID: 22973040
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac.
    Brandariz-Nuñez A; Valle-Casuso JC; White TE; Laguette N; Benkirane M; Brojatsch J; Diaz-Griffero F
    Retrovirology; 2012 Jun; 9():49. PubMed ID: 22691373
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HIV-2 and SIVmac accessory virulence factor Vpx down-regulates SAMHD1 enzyme catalysis prior to proteasome-dependent degradation.
    DeLucia M; Mehrens J; Wu Y; Ahn J
    J Biol Chem; 2013 Jun; 288(26):19116-26. PubMed ID: 23677995
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural basis of lentiviral subversion of a cellular protein degradation pathway.
    Schwefel D; Groom HC; Boucherit VC; Christodoulou E; Walker PA; Stoye JP; Bishop KN; Taylor IA
    Nature; 2014 Jan; 505(7482):234-8. PubMed ID: 24336198
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Degradation of SAMHD1 by Vpx Is Independent of Uncoating.
    Jáuregui P; Logue EC; Schultz ML; Fung S; Landau NR
    J Virol; 2015 May; 89(10):5701-13. PubMed ID: 25762741
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly.
    Wang H; Guo H; Su J; Rui Y; Zheng W; Gao W; Zhang W; Li Z; Liu G; Markham RB; Wei W; Yu XF
    J Virol; 2017 May; 91(9):. PubMed ID: 28202763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply.
    Dragin L; Nguyen LA; Lahouassa H; Sourisce A; Kim B; Ramirez BC; Margottin-Goguet F
    Retrovirology; 2013 Mar; 10():30. PubMed ID: 23497353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vpx rescue of HIV-1 from the antiviral state in mature dendritic cells is independent of the intracellular deoxynucleotide concentration.
    Reinhard C; Bottinelli D; Kim B; Luban J
    Retrovirology; 2014 Feb; 11():12. PubMed ID: 24485168
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1.
    Ahn J; Hao C; Yan J; DeLucia M; Mehrens J; Wang C; Gronenborn AM; Skowronski J
    J Biol Chem; 2012 Apr; 287(15):12550-8. PubMed ID: 22362772
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel DCAF1-binding motif required for Vpx-mediated degradation of nuclear SAMHD1 and Vpr-induced G2 arrest.
    Wei W; Guo H; Han X; Liu X; Zhou X; Zhang W; Yu XF
    Cell Microbiol; 2012 Nov; 14(11):1745-56. PubMed ID: 22776683
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HD domain of SAMHD1 influences Vpx-induced degradation at a post-interaction step.
    Kang J; Hou J; Zhao K; Yu XF; Du J
    Biochem Biophys Res Commun; 2016 Feb; 470(3):690-696. PubMed ID: 26779819
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.
    Baldauf HM; Stegmann L; Schwarz SM; Ambiel I; Trotard M; Martin M; Burggraf M; Lenzi GM; Lejk H; Pan X; Fregoso OI; Lim ES; Abraham L; Nguyen LA; Rutsch F; König R; Kim B; Emerman M; Fackler OT; Keppler OT
    Proc Natl Acad Sci U S A; 2017 Mar; 114(10):2729-2734. PubMed ID: 28228523
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors.
    Wu Y; Koharudin LMI; Mehrens J; DeLucia M; Byeon CH; Byeon IL; Calero G; Ahn J; Gronenborn AM
    J Biol Chem; 2015 Jul; 290(29):17935-17945. PubMed ID: 26045556
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the interactions between SIVrcm Vpx and red-capped mangabey SAMHD1.
    Li J; Xu F; Hu S; Zhou J; Mei S; Zhao X; Cen S; Jin Q; Liang C; Guo F
    Biochem J; 2015 Jun; 468(2):303-13. PubMed ID: 25791246
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx.
    Martin MM; Matkovic R; Larrous P; Morel M; Lasserre A; Vauthier V; Margottin-Goguet F
    PLoS Pathog; 2021 Oct; 17(10):e1009609. PubMed ID: 34699574
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1.
    Fregoso OI; Ahn J; Wang C; Mehrens J; Skowronski J; Emerman M
    PLoS Pathog; 2013; 9(7):e1003496. PubMed ID: 23874202
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interference with SAMHD1 Restores Late Gene Expression of Modified Vaccinia Virus Ankara in Human Dendritic Cells and Abrogates Type I Interferon Expression.
    Sliva K; Martin J; von Rhein C; Herrmann T; Weyrich A; Toda M; Schnierle BS
    J Virol; 2019 Nov; 93(22):. PubMed ID: 31462561
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein.
    Hrecka K; Hao C; Gierszewska M; Swanson SK; Kesik-Brodacka M; Srivastava S; Florens L; Washburn MP; Skowronski J
    Nature; 2011 Jun; 474(7353):658-61. PubMed ID: 21720370
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.