BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

531 related articles for article (PubMed ID: 24726384)

  • 1. Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.
    Xie H; Hanai J; Ren JG; Kats L; Burgess K; Bhargava P; Signoretti S; Billiard J; Duffy KJ; Grant A; Wang X; Lorkiewicz PK; Schatzman S; Bousamra M; Lane AN; Higashi RM; Fan TW; Pandolfi PP; Sukhatme VP; Seth P
    Cell Metab; 2014 May; 19(5):795-809. PubMed ID: 24726384
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage.
    Deng H; Gao Y; Trappetti V; Hertig D; Karatkevich D; Losmanova T; Urzi C; Ge H; Geest GA; Bruggmann R; Djonov V; Nuoffer JM; Vermathen P; Zamboni N; Riether C; Ochsenbein A; Peng RW; Kocher GJ; Schmid RA; Dorn P; Marti TM
    Cell Mol Life Sci; 2022 Jul; 79(8):445. PubMed ID: 35877003
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells.
    Yang Y; Su D; Zhao L; Zhang D; Xu J; Wan J; Fan S; Chen M
    Oncotarget; 2014 Dec; 5(23):11886-96. PubMed ID: 25361010
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation on the inhibition of pyrrol-2-yl ethanone derivatives to lactate dehydrogenase and anticancer activities.
    Lu NN; Weng ZY; Chen QY; Boison D; Xiao XX; Gao J
    Spectrochim Acta A Mol Biomol Spectrosc; 2016 Aug; 165():21-25. PubMed ID: 27104676
    [TBL] [Abstract][Full Text] [Related]  

  • 5. l-Lactate metabolism in HEP G2 cell mitochondria due to the l-lactate dehydrogenase determines the occurrence of the lactate/pyruvate shuttle and the appearance of oxaloacetate, malate and citrate outside mitochondria.
    Pizzuto R; Paventi G; Porcile C; Sarnataro D; Daniele A; Passarella S
    Biochim Biophys Acta; 2012 Sep; 1817(9):1679-90. PubMed ID: 22659615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells.
    Fan J; Hitosugi T; Chung TW; Xie J; Ge Q; Gu TL; Polakiewicz RD; Chen GZ; Boggon TJ; Lonial S; Khuri FR; Kang S; Chen J
    Mol Cell Biol; 2011 Dec; 31(24):4938-50. PubMed ID: 21969607
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relationships between LDH-A, lactate, and metastases in 4T1 breast tumors.
    Rizwan A; Serganova I; Khanin R; Karabeber H; Ni X; Thakur S; Zakian KL; Blasberg R; Koutcher JA
    Clin Cancer Res; 2013 Sep; 19(18):5158-69. PubMed ID: 23833310
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation.
    Chen X; Gao A; Zhang F; Yang Z; Wang S; Fang Y; Li J; Wang J; Shi W; Wang L; Zheng Y; Sun Y
    Theranostics; 2021; 11(7):3392-3416. PubMed ID: 33537094
    [No Abstract]   [Full Text] [Related]  

  • 9. Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function.
    Rajeshkumar NV; Dutta P; Yabuuchi S; de Wilde RF; Martinez GV; Le A; Kamphorst JJ; Rabinowitz JD; Jain SK; Hidalgo M; Dang CV; Gillies RJ; Maitra A
    Cancer Res; 2015 Aug; 75(16):3355-64. PubMed ID: 26113084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.
    Seth P; Grant A; Tang J; Vinogradov E; Wang X; Lenkinski R; Sukhatme VP
    Neoplasia; 2011 Jan; 13(1):60-71. PubMed ID: 21245941
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Myristica fragrans Suppresses Tumor Growth and Metabolism by Inhibiting Lactate Dehydrogenase A.
    Kim EY; Choi HJ; Park MJ; Jung YS; Lee SO; Kim KJ; Choi JH; Chung TW; Ha KT
    Am J Chin Med; 2016; 44(5):1063-79. PubMed ID: 27430914
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Downregulation of miR-200c Promotes Lactate Dehydrogenase A Expression and Non-Small Cell Lung Cancer Progression.
    Lei W; Kang W; Nan Y; Lei Z; Zhongdong L; Demin L; Lei S; Hairong H
    Oncol Res; 2018 Aug; 26(7):1015-1022. PubMed ID: 29321091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lactate Dehydrogenase and its clinical significance in pancreatic and thoracic cancers.
    Comandatore A; Franczak M; Smolenski RT; Morelli L; Peters GJ; Giovannetti E
    Semin Cancer Biol; 2022 Nov; 86(Pt 2):93-100. PubMed ID: 36096316
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Restoration of mutant K-Ras repressed miR-199b inhibits K-Ras mutant non-small cell lung cancer progression.
    Jin H; Jang Y; Cheng N; Li Q; Cui PF; Zhou ZW; Jiang HL; Cho MH; Westover KD; Tan QY; Xu CX
    J Exp Clin Cancer Res; 2019 Apr; 38(1):165. PubMed ID: 30987652
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
    Ždralević M; Brand A; Di Ianni L; Dettmer K; Reinders J; Singer K; Peter K; Schnell A; Bruss C; Decking SM; Koehl G; Felipe-Abrio B; Durivault J; Bayer P; Evangelista M; O'Brien T; Oefner PJ; Renner K; Pouysségur J; Kreutz M
    J Biol Chem; 2018 Oct; 293(41):15947-15961. PubMed ID: 30158244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stable shRNA Silencing of Lactate Dehydrogenase A (LDHA) in Human MDA-MB-231 Breast Cancer Cells Fails to Alter Lactic Acid Production, Glycolytic Activity, ATP or Survival.
    Mack N; Mazzio EA; Bauer D; Flores-Rozas H; Soliman KF
    Anticancer Res; 2017 Mar; 37(3):1205-1212. PubMed ID: 28314283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of LDH-A and glutaminase inhibition in vivo by hyperpolarized 13C-pyruvate magnetic resonance spectroscopy of tumors.
    Dutta P; Le A; Vander Jagt DL; Tsukamoto T; Martinez GV; Dang CV; Gillies RJ
    Cancer Res; 2013 Jul; 73(14):4190-5. PubMed ID: 23722553
    [TBL] [Abstract][Full Text] [Related]  

  • 18. LDH-A silencing suppresses breast cancer tumorigenicity through induction of oxidative stress mediated mitochondrial pathway apoptosis.
    Wang ZY; Loo TY; Shen JG; Wang N; Wang DM; Yang DP; Mo SL; Guan XY; Chen JP
    Breast Cancer Res Treat; 2012 Feb; 131(3):791-800. PubMed ID: 21452021
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lactate-dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1.
    Kayser G; Kassem A; Sienel W; Schulte-Uentrop L; Mattern D; Aumann K; Stickeler E; Werner M; Passlick B; zur Hausen A
    Diagn Pathol; 2010 Apr; 5():22. PubMed ID: 20385008
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The drs tumor suppressor regulates glucose metabolism via lactate dehydrogenase-B.
    Tambe Y; Hasebe M; Kim CJ; Yamamoto A; Inoue H
    Mol Carcinog; 2016 Jan; 55(1):52-63. PubMed ID: 25620379
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.