247 related articles for article (PubMed ID: 24727379)
1. Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4.
Gu J; Babayeva ND; Suwa Y; Baranovskiy AG; Price DH; Tahirov TH
Cell Cycle; 2014; 13(11):1788-97. PubMed ID: 24727379
[TBL] [Abstract][Full Text] [Related]
2. The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.
Schulze-Gahmen U; Upton H; Birnberg A; Bao K; Chou S; Krogan NJ; Zhou Q; Alber T
Elife; 2013 Mar; 2():e00327. PubMed ID: 23471103
[TBL] [Abstract][Full Text] [Related]
3. Super elongation complex promotes early HIV transcription and its function is modulated by P-TEFb.
Kuzmina A; Krasnopolsky S; Taube R
Transcription; 2017 May; 8(3):133-149. PubMed ID: 28340332
[TBL] [Abstract][Full Text] [Related]
4. Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.
Schulze-Gahmen U; Echeverria I; Stjepanovic G; Bai Y; Lu H; Schneidman-Duhovny D; Doudna JA; Zhou Q; Sali A; Hurley JH
Elife; 2016 Oct; 5():. PubMed ID: 27731797
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure of HIV-1 Tat complexed with human P-TEFb.
Tahirov TH; Babayeva ND; Varzavand K; Cooper JJ; Sedore SC; Price DH
Nature; 2010 Jun; 465(7299):747-51. PubMed ID: 20535204
[TBL] [Abstract][Full Text] [Related]
6. A single point mutation in cyclin T1 eliminates binding to Hexim1, Cdk9 and RNA but not to AFF4 and enforces repression of HIV transcription.
Kuzmina A; Verstraete N; Galker S; Maatook M; Bensaude O; Taube R
Retrovirology; 2014 Jul; 11():51. PubMed ID: 24985467
[TBL] [Abstract][Full Text] [Related]
7. AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.
Schulze-Gahmen U; Lu H; Zhou Q; Alber T
Elife; 2014 Apr; 3():e02375. PubMed ID: 24843025
[TBL] [Abstract][Full Text] [Related]
8. AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.
Lu H; Li Z; Xue Y; Schulze-Gahmen U; Johnson JR; Krogan NJ; Alber T; Zhou Q
Proc Natl Acad Sci U S A; 2014 Jan; 111(1):E15-24. PubMed ID: 24367103
[TBL] [Abstract][Full Text] [Related]
9. HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription.
He N; Liu M; Hsu J; Xue Y; Chou S; Burlingame A; Krogan NJ; Alber T; Zhou Q
Mol Cell; 2010 May; 38(3):428-38. PubMed ID: 20471948
[TBL] [Abstract][Full Text] [Related]
10. Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.
Lu H; Li Z; Zhang W; Schulze-Gahmen U; Xue Y; Zhou Q
Nucleic Acids Res; 2015 Jul; 43(12):5868-79. PubMed ID: 26007649
[TBL] [Abstract][Full Text] [Related]
11. Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter.
Fong YW; Zhou Q
Mol Cell Biol; 2000 Aug; 20(16):5897-907. PubMed ID: 10913173
[TBL] [Abstract][Full Text] [Related]
12. Developmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcription.
Wang Q; Young TM; Mathews MB; Pe'ery T
J Mol Biol; 2007 Mar; 367(3):630-46. PubMed ID: 17289077
[TBL] [Abstract][Full Text] [Related]
13. Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.
Mbonye U; Wang B; Gokulrangan G; Shi W; Yang S; Karn J
J Biol Chem; 2018 Jun; 293(26):10009-10025. PubMed ID: 29743242
[TBL] [Abstract][Full Text] [Related]
14. CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA.
Garber ME; Mayall TP; Suess EM; Meisenhelder J; Thompson NE; Jones KA
Mol Cell Biol; 2000 Sep; 20(18):6958-69. PubMed ID: 10958691
[TBL] [Abstract][Full Text] [Related]
15. HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.
Chou S; Upton H; Bao K; Schulze-Gahmen U; Samelson AJ; He N; Nowak A; Lu H; Krogan NJ; Zhou Q; Alber T
Proc Natl Acad Sci U S A; 2013 Jan; 110(2):E123-31. PubMed ID: 23251033
[TBL] [Abstract][Full Text] [Related]
16. HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.
Sobhian B; Laguette N; Yatim A; Nakamura M; Levy Y; Kiernan R; Benkirane M
Mol Cell; 2010 May; 38(3):439-51. PubMed ID: 20471949
[TBL] [Abstract][Full Text] [Related]
17. MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding.
Asamitsu K; Hirokawa T; Okamoto T
PLoS One; 2017; 12(2):e0171727. PubMed ID: 28178316
[TBL] [Abstract][Full Text] [Related]
18. Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes.
Mbonye UR; Gokulrangan G; Datt M; Dobrowolski C; Cooper M; Chance MR; Karn J
PLoS Pathog; 2013; 9(5):e1003338. PubMed ID: 23658523
[TBL] [Abstract][Full Text] [Related]
19. A Cyclin T1 point mutation that abolishes positive transcription elongation factor (P-TEFb) binding to Hexim1 and HIV tat.
Verstraete N; Kuzmina A; Diribarne G; Nguyen VT; Kobbi L; Ludanyi M; Taube R; Bensaude O
Retrovirology; 2014 Jul; 11():50. PubMed ID: 24985203
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of human immunodeficiency virus type 1 replication by RNA interference directed against human transcription elongation factor P-TEFb (CDK9/CyclinT1).
Chiu YL; Cao H; Jacque JM; Stevenson M; Rana TM
J Virol; 2004 Mar; 78(5):2517-29. PubMed ID: 14963154
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
