BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 24732207)

  • 1. Developmental processes regulated by the 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway: highlights from animal studies.
    Eisa-Beygi S; Ekker M; Moon TW; Macdonald RL; Wen XY
    Reprod Toxicol; 2014 Jul; 46():115-20. PubMed ID: 24732207
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway.
    Eisa-Beygi S; Hatch G; Noble S; Ekker M; Moon TW
    Dev Biol; 2013 Jan; 373(2):258-66. PubMed ID: 23206891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene.
    Ohashi K; Osuga J; Tozawa R; Kitamine T; Yagyu H; Sekiya M; Tomita S; Okazaki H; Tamura Y; Yahagi N; Iizuka Y; Harada K; Gotoda T; Shimano H; Yamada N; Ishibashi S
    J Biol Chem; 2003 Oct; 278(44):42936-41. PubMed ID: 12920113
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mutation in zebrafish hmgcr1b reveals a role for isoprenoids in vertebrate heart-tube formation.
    D'Amico L; Scott IC; Jungblut B; Stainier DY
    Curr Biol; 2007 Feb; 17(3):252-9. PubMed ID: 17276918
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Explication of interactions between HMGCR isoform 2 and various statins through In silico modeling and docking.
    Karthik MV; Satya Deepak MV; Shukla P
    Comput Biol Med; 2012 Feb; 42(2):156-63. PubMed ID: 22177940
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hmgcr in the corpus allatum controls sexual dimorphism of locomotor activity and body size via the insulin pathway in Drosophila.
    Belgacem YH; Martin JR
    PLoS One; 2007 Jan; 2(1):e187. PubMed ID: 17264888
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival.
    Lacher SM; Bruttger J; Kalt B; Berthelet J; Rajalingam K; Wörtge S; Waisman A
    Cell Death Dis; 2017 May; 8(5):e2824. PubMed ID: 28542128
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proto oncogene/eukaryotic translation initiation factor (eIF) 4E attenuates mevalonate-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase synthesis.
    Buechler RD; Peffley DM
    Mol Carcinog; 2004 Sep; 41(1):39-53. PubMed ID: 15352124
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HMG-CoA reductase guides migrating primordial germ cells.
    Van Doren M; Broihier HT; Moore LA; Lehmann R
    Nature; 1998 Dec; 396(6710):466-9. PubMed ID: 9853754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Resveratrol inhibits the mevalonate pathway and potentiates the antiproliferative effects of simvastatin in rat theca-interstitial cells.
    Wong DH; Villanueva JA; Cress AB; Sokalska A; Ortega I; Duleba AJ
    Fertil Steril; 2011 Nov; 96(5):1252-8. PubMed ID: 21907337
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR).
    Sharpe LJ; Brown AJ
    J Biol Chem; 2013 Jun; 288(26):18707-15. PubMed ID: 23696639
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [The key enzyme of cholesterol synthesis pathway: HMG-CoA reductase and disease].
    Wang W; Tong TJ
    Sheng Li Ke Xue Jin Zhan; 1999 Jan; 30(1):5-9. PubMed ID: 12532841
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase.
    De Giorgi M; Jarrett KE; Burton JC; Doerfler AM; Hurley A; Li A; Hsu RH; Furgurson M; Patel KR; Han J; Borchers CH; Lagor WR
    J Lipid Res; 2020 Dec; 61(12):1675-1686. PubMed ID: 33109681
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulatory effects of HMG-CoA reductase inhibitors in diabetic microangiopathy.
    Danesh FR; Kanwar YS
    FASEB J; 2004 May; 18(7):805-15. PubMed ID: 15117885
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.
    Lipkin SM; Chao EC; Moreno V; Rozek LS; Rennert H; Pinchev M; Dizon D; Rennert G; Kopelovich L; Gruber SB
    Cancer Prev Res (Phila); 2010 May; 3(5):597-603. PubMed ID: 20403997
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis.
    Choi J; Mouillesseaux K; Wang Z; Fiji HD; Kinderman SS; Otto GW; Geisler R; Kwon O; Chen JN
    Development; 2011 Mar; 138(6):1173-81. PubMed ID: 21307094
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins.
    Mo H; Jeter R; Bachmann A; Yount ST; Shen CL; Yeganehjoo H
    Front Pharmacol; 2018; 9():1515. PubMed ID: 30662405
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate.
    Straka MS; Panini SR
    Arch Biochem Biophys; 1995 Feb; 317(1):235-43. PubMed ID: 7872789
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Liver-specific deletion of 3-hydroxy-3-methylglutaryl coenzyme A reductase causes hepatic steatosis and death.
    Nagashima S; Yagyu H; Ohashi K; Tazoe F; Takahashi M; Ohshiro T; Bayasgalan T; Okada K; Sekiya M; Osuga J; Ishibashi S
    Arterioscler Thromb Vasc Biol; 2012 Aug; 32(8):1824-31. PubMed ID: 22701022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The 3-hydroxy-3-methylglutaryl coenzyme-A reductases from fungi: a proposal as a therapeutic target and as a study model.
    Andrade-Pavón D; Sánchez-Sandoval E; Rosales-Acosta B; Ibarra JA; Tamariz J; Hernández-Rodríguez C; Villa-Tanaca L
    Rev Iberoam Micol; 2014; 31(1):81-5. PubMed ID: 24270073
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.