BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 24733901)

  • 1. MicroRNAs are critical regulators of tuberous sclerosis complex and mTORC1 activity in the size control of the Xenopus kidney.
    Romaker D; Kumar V; Cerqueira DM; Cox RM; Wessely O
    Proc Natl Acad Sci U S A; 2014 Apr; 111(17):6335-40. PubMed ID: 24733901
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MicroRNA148b-3p inhibits mTORC1-dependent apoptosis in diabetes by repressing TNFR2 in proximal tubular cells.
    Kuwagata S; Kume S; Chin-Kanasaki M; Araki H; Araki S; Nakazawa J; Sugaya T; Koya D; Haneda M; Maegawa H; Uzu T
    Kidney Int; 2016 Dec; 90(6):1211-1225. PubMed ID: 27591086
    [TBL] [Abstract][Full Text] [Related]  

  • 3. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization.
    Gan B; Sahin E; Jiang S; Sanchez-Aguilera A; Scott KL; Chin L; Williams DA; Kwiatkowski DJ; DePinho RA
    Proc Natl Acad Sci U S A; 2008 Dec; 105(49):19384-9. PubMed ID: 19052232
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
    Di Nardo A; Wertz MH; Kwiatkowski E; Tsai PT; Leech JD; Greene-Colozzi E; Goto J; Dilsiz P; Talos DM; Clish CB; Kwiatkowski DJ; Sahin M
    Hum Mol Genet; 2014 Jul; 23(14):3865-74. PubMed ID: 24599401
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTORC1: turning off is just as important as turning on.
    Benjamin D; Hall MN
    Cell; 2014 Feb; 156(4):627-8. PubMed ID: 24529368
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of mTORC1 in collecting ducts causes hyperkalemia.
    Chen Z; Dong H; Jia C; Song Q; Chen J; Zhang Y; Lai P; Fan X; Zhou X; Liu M; Lin J; Yang C; Li M; Gao T; Bai X
    J Am Soc Nephrol; 2014 Mar; 25(3):534-45. PubMed ID: 24203997
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel Hap1-Tsc1 interaction regulates neuronal mTORC1 signaling and morphogenesis in the brain.
    Mejia LA; Litterman N; Ikeuchi Y; de la Torre-Ubieta L; Bennett EJ; Zhang C; Harper JW; Bonni A
    J Neurosci; 2013 Nov; 33(46):18015-21. PubMed ID: 24227713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hyperactivation of mammalian target of rapamycin complex 1 (mTORC1) promotes breast cancer progression through enhancing glucose starvation-induced autophagy and Akt signaling.
    Chen Y; Wei H; Liu F; Guan JL
    J Biol Chem; 2014 Jan; 289(2):1164-73. PubMed ID: 24275666
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway.
    Zhang HH; Huang J; Düvel K; Boback B; Wu S; Squillace RM; Wu CL; Manning BD
    PLoS One; 2009 Jul; 4(7):e6189. PubMed ID: 19593385
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fetal brain mTOR signaling activation in tuberous sclerosis complex.
    Tsai V; Parker WE; Orlova KA; Baybis M; Chi AW; Berg BD; Birnbaum JF; Estevez J; Okochi K; Sarnat HB; Flores-Sarnat L; Aronica E; Crino PB
    Cereb Cortex; 2014 Feb; 24(2):315-27. PubMed ID: 23081885
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of mTORC1 signaling by pH.
    Balgi AD; Diering GH; Donohue E; Lam KK; Fonseca BD; Zimmerman C; Numata M; Roberge M
    PLoS One; 2011; 6(6):e21549. PubMed ID: 21738705
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
    Menon S; Dibble CC; Talbott G; Hoxhaj G; Valvezan AJ; Takahashi H; Cantley LC; Manning BD
    Cell; 2014 Feb; 156(4):771-85. PubMed ID: 24529379
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IRS1Ser³⁰⁷ phosphorylation does not mediate mTORC1-induced insulin resistance.
    Herrema H; Lee J; Zhou Y; Copps KD; White MF; Ozcan U
    Biochem Biophys Res Commun; 2014 Jan; 443(2):689-93. PubMed ID: 24333417
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
    Malhowski AJ; Hira H; Bashiruddin S; Warburton R; Goto J; Robert B; Kwiatkowski DJ; Finlay GA
    Hum Mol Genet; 2011 Apr; 20(7):1290-305. PubMed ID: 21212099
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ursolic acid inhibits leucine-stimulated mTORC1 signaling by suppressing mTOR localization to lysosome.
    Ou X; Liu M; Luo H; Dong LQ; Liu F
    PLoS One; 2014; 9(4):e95393. PubMed ID: 24740400
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt.
    Kenerson HL; Subramanian S; McIntyre R; Kazami M; Yeung RS
    PLoS One; 2015; 10(2):e0117000. PubMed ID: 25646773
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway.
    Yang T; Zhu L; Zhai Y; Zhao Q; Peng J; Zhang H; Yang Z; Zhang L; Ding W; Zhao Y
    Cell Mol Immunol; 2016 Sep; 13(5):640-50. PubMed ID: 27593484
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation.
    Cao J; Tyburczy ME; Moss J; Darling TN; Widlund HR; Kwiatkowski DJ
    J Clin Invest; 2017 Jan; 127(1):349-364. PubMed ID: 27918305
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome.
    Venkatesh A; Ma S; Punzo C
    Cell Death Dis; 2016 Jun; 7(6):e2279. PubMed ID: 27362797
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.