BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 24735732)

  • 1. PI3K inhibitors as potential therapeutics for autoimmune disease.
    Ball J; Archer S; Ward S
    Drug Discov Today; 2014 Aug; 19(8):1195-9. PubMed ID: 24735732
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Role of PI3K Isoforms in Autoimmune Disease.
    Ward SG
    Curr Top Microbiol Immunol; 2022; 436():337-347. PubMed ID: 36243851
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of PI3K signaling spurs new therapeutic opportunities in inflammatory/autoimmune diseases and hematological malignancies.
    Foster JG; Blunt MD; Carter E; Ward SG
    Pharmacol Rev; 2012 Oct; 64(4):1027-54. PubMed ID: 23023033
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Therapeutic potential of phosphoinositide 3-kinase inhibitors.
    Ward S; Sotsios Y; Dowden J; Bruce I; Finan P
    Chem Biol; 2003 Mar; 10(3):207-13. PubMed ID: 12670534
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PI3 kinase inhibitors in the clinic: an update.
    Kurtz JE; Ray-Coquard I
    Anticancer Res; 2012 Jul; 32(7):2463-70. PubMed ID: 22753702
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isoform-specific phosphoinositide 3-kinase inhibitors as therapeutic agents.
    Ward SG; Finan P
    Curr Opin Pharmacol; 2003 Aug; 3(4):426-34. PubMed ID: 12901953
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PI3K inhibitors in cardiovascular disease.
    Eisenreich A; Rauch U
    Cardiovasc Ther; 2011 Feb; 29(1):29-36. PubMed ID: 20626398
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PI3K inhibitors in inflammation, autoimmunity and cancer.
    Stark AK; Sriskantharajah S; Hessel EM; Okkenhaug K
    Curr Opin Pharmacol; 2015 Aug; 23():82-91. PubMed ID: 26093105
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Therapeutic applications of PI3K inhibitors in cardiovascular diseases.
    Ghigo A; Morello F; Perino A; Hirsch E
    Future Med Chem; 2013 Mar; 5(4):479-92. PubMed ID: 23495693
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective and potent small-molecule inhibitors of PI3Ks.
    Jeong Y; Kwon D; Hong S
    Future Med Chem; 2014 May; 6(7):737-56. PubMed ID: 24941870
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease.
    Venable JD; Ameriks MK; Blevitt JM; Thurmond RL; Fung-Leung WP
    Recent Pat Inflamm Allergy Drug Discov; 2010 Jan; 4(1):1-15. PubMed ID: 20017720
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511.
    Norman MH; Andrews KL; Bo YY; Booker SK; Caenepeel S; Cee VJ; D'Angelo ND; Freeman DJ; Herberich BJ; Hong FT; Jackson CL; Jiang J; Lanman BA; Liu L; McCarter JD; Mullady EL; Nishimura N; Pettus LH; Reed AB; Miguel TS; Smith AL; Stec MM; Tadesse S; Tasker A; Aidasani D; Zhu X; Subramanian R; Tamayo NA; Wang L; Whittington DA; Wu B; Wu T; Wurz RP; Yang K; Zalameda L; Zhang N; Hughes PE
    J Med Chem; 2012 Sep; 55(17):7796-816. PubMed ID: 22897589
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methods to measure the enzymatic activity of PI3Ks.
    Ciraolo E; Gulluni F; Hirsch E
    Methods Enzymol; 2014; 543():115-40. PubMed ID: 24924130
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heterocyclic compounds and their uses: a patent evaluation of WO2010151735A2.
    Scozzafava A; Supuran CT
    Expert Opin Ther Pat; 2011 May; 21(5):803-6. PubMed ID: 21434841
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of highly potent and selective PI3Kδ inhibitors.
    Marcoux D; Qin LY; Ruan Z; Shi Q; Ruan Q; Weigelt C; Qiu H; Schieven G; Hynes J; Bhide R; Poss M; Tino J
    Bioorg Med Chem Lett; 2017 Jul; 27(13):2849-2853. PubMed ID: 28209465
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective pharmacological inhibition of phosphoinositide 3-kinase p110delta opposes the progression of autoimmune diabetes in non-obese diabetic (NOD) mice.
    Durand CA; Richer MJ; Brenker K; Graves M; Shanina I; Choi K; Horwitz MS; Puri KD; Gold MR
    Autoimmunity; 2013 Feb; 46(1):62-73. PubMed ID: 23039284
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphoinositide 3-kinases in health and disease.
    Ghigo A; Morello F; Perino A; Hirsch E
    Subcell Biochem; 2012; 58():183-213. PubMed ID: 22403077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PI3K Signaling in Chronic Obstructive Pulmonary Disease: Mechanisms, Targets, and Therapy.
    Pirozzi F; Ren K; Murabito A; Ghigo A
    Curr Med Chem; 2019; 26(16):2791-2800. PubMed ID: 29557740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor efficacy of PKI-587, a highly potent dual PI3K/mTOR kinase inhibitor.
    Mallon R; Feldberg LR; Lucas J; Chaudhary I; Dehnhardt C; Santos ED; Chen Z; dos Santos O; Ayral-Kaloustian S; Venkatesan A; Hollander I
    Clin Cancer Res; 2011 May; 17(10):3193-203. PubMed ID: 21325073
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The pathophysiological roles of PI3Ks and therapeutic potential of selective inhibitors in allergic inflammation.
    Takeda M; Ito W; Tanabe M; Ueki S; Kihara J; Kato H; Tanigai T; Kayaba H; Sasaki T; Chihara J
    Int Arch Allergy Immunol; 2010; 152 Suppl 1():90-5. PubMed ID: 20523070
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.