These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 24736273)

  • 1. Protein dynamics of the HIF-2α PAS-B domain upon heterodimerization and ligand binding.
    Masetti M; Falchi F; Recanatini M
    PLoS One; 2014; 9(4):e94986. PubMed ID: 24736273
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ligand-induced perturbation of the HIF-2α:ARNT dimer dynamics.
    Motta S; Minici C; Corrada D; Bonati L; Pandini A
    PLoS Comput Biol; 2018 Feb; 14(2):e1006021. PubMed ID: 29489822
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular dynamics investigation of stereoselective inhibition mechanism of HIF-2α/ARNT heterodimer.
    Sun DR; Zheng QC; Zhang HX
    J Mol Recognit; 2018 Jan; 31(1):. PubMed ID: 28990233
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization.
    Guo Y; Scheuermann TH; Partch CL; Tomchick DR; Gardner KH
    J Biol Chem; 2015 Mar; 290(12):7707-21. PubMed ID: 25627682
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular Dynamics Simulations of the Hypoxia-Inducible Factor PAS-B Domain Confirm That Internally Bound Water Molecules Function To Stabilize the Protein Core for Ligand Binding.
    Chong AS; Anderson PC
    Biochemistry; 2020 Feb; 59(4):450-459. PubMed ID: 31868344
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor.
    Rogers JL; Bayeh L; Scheuermann TH; Longgood J; Key J; Naidoo J; Melito L; Shokri C; Frantz DE; Bruick RK; Gardner KH; MacMillan JB; Tambar UK
    J Med Chem; 2013 Feb; 56(4):1739-47. PubMed ID: 23363003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of novel direct small-molecule inhibitors targeting HIF-2α using structure-based virtual screening, molecular dynamics simulation, and MM-GBSA calculations.
    Yazdani B; Sirous H; Enguita FJ; Brogi S; Wing PAC; Fassihi A
    Mol Divers; 2024 Jun; 28(3):1203-1224. PubMed ID: 37120484
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
    Scheuermann TH; Tomchick DR; Machius M; Guo Y; Bruick RK; Gardner KH
    Proc Natl Acad Sci U S A; 2009 Jan; 106(2):450-5. PubMed ID: 19129502
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular modeling on HIF-2α-ARNT dimer destabilization caused by R171A and/or V192D mutations in HIF-2α.
    Chen YJ; Huang BY; Yang CN
    J Mol Graph Model; 2018 Jan; 79():35-45. PubMed ID: 29132019
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
    Wu D; Su X; Potluri N; Kim Y; Rastinejad F
    Elife; 2016 Oct; 5():. PubMed ID: 27782878
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Coactivators necessary for transcriptional output of the hypoxia inducible factor, HIF, are directly recruited by ARNT PAS-B.
    Partch CL; Gardner KH
    Proc Natl Acad Sci U S A; 2011 May; 108(19):7739-44. PubMed ID: 21512126
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural integration in hypoxia-inducible factors.
    Wu D; Potluri N; Lu J; Kim Y; Rastinejad F
    Nature; 2015 Aug; 524(7565):303-8. PubMed ID: 26245371
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.
    Card PB; Erbel PJ; Gardner KH
    J Mol Biol; 2005 Oct; 353(3):664-77. PubMed ID: 16181639
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bidirectional modulation of HIF-2 activity through chemical ligands.
    Wu D; Su X; Lu J; Li S; Hood BL; Vasile S; Potluri N; Diao X; Kim Y; Khorasanizadeh S; Rastinejad F
    Nat Chem Biol; 2019 Apr; 15(4):367-376. PubMed ID: 30804532
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain.
    Coban MA; Blackburn PR; Whitelaw ML; Haelst MMV; Atwal PS; Caulfield TR
    Biomolecules; 2020 Sep; 10(9):. PubMed ID: 32932609
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computational Repacking of HIF-2α Cavity Replaces Water-Based Stabilized Core.
    Corrêa F; Key J; Kuhlman B; Gardner KH
    Structure; 2016 Nov; 24(11):1918-1927. PubMed ID: 27667693
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.
    Erbel PJ; Card PB; Karakuzu O; Bruick RK; Gardner KH
    Proc Natl Acad Sci U S A; 2003 Dec; 100(26):15504-9. PubMed ID: 14668441
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural characterization of mammalian bHLH-PAS transcription factors.
    Wu D; Rastinejad F
    Curr Opin Struct Biol; 2017 Apr; 43():1-9. PubMed ID: 27721191
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular imaging: into in vivo interaction of HIF-1alpha and HIF-2alpha with ARNT.
    Konietzny R; König A; Wotzlaw C; Bernadini A; Berchner-Pfannschmidt U; Fandrey J
    Ann N Y Acad Sci; 2009 Oct; 1177():74-81. PubMed ID: 19845609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Decoding Allosteric Control in Hypoxia-Inducible Factors.
    Zhuang J; Shang Q; Rastinejad F; Wu D
    J Mol Biol; 2024 Feb; 436(3):168352. PubMed ID: 37935255
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.