These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Microglia in juvenile neuronal ceroid lipofuscinosis are primed toward a pro-inflammatory phenotype. Xiong J; Kielian T J Neurochem; 2013 Oct; 127(2):245-58. PubMed ID: 23919525 [TBL] [Abstract][Full Text] [Related]
5. Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus serotype rh.10 vector expressing the human CLN3 gene. Sondhi D; Scott EC; Chen A; Hackett NR; Wong AM; Kubiak A; Nelvagal HR; Pearse Y; Cotman SL; Cooper JD; Crystal RG Hum Gene Ther; 2014 Mar; 25(3):223-39. PubMed ID: 24372003 [TBL] [Abstract][Full Text] [Related]
6. Cln3-mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl-protein thioesterases-1 (Ppt1)-protein and Ppt1-enzyme activity in the lysosome. Appu AP; Bagh MB; Sadhukhan T; Mondal A; Casey S; Mukherjee AB J Inherit Metab Dis; 2019 Sep; 42(5):944-954. PubMed ID: 31025705 [TBL] [Abstract][Full Text] [Related]
7. Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium. Zhong Y; Mohan K; Liu J; Al-Attar A; Lin P; Flight RM; Sun Q; Warmoes MO; Deshpande RR; Liu H; Jung KS; Mitov MI; Lin N; Butterfield DA; Lu S; Liu J; Moseley HNB; Fan TWM; Kleinman ME; Wang QJ Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165883. PubMed ID: 32592935 [TBL] [Abstract][Full Text] [Related]
8. Thalamocortical neuron loss and localized astrocytosis in the Cln3Deltaex7/8 knock-in mouse model of Batten disease. Pontikis CC; Cotman SL; MacDonald ME; Cooper JD Neurobiol Dis; 2005 Dec; 20(3):823-36. PubMed ID: 16006136 [TBL] [Abstract][Full Text] [Related]
9. Efficacy of phosphodiesterase-4 inhibitors in juvenile Batten disease (CLN3). Aldrich A; Bosch ME; Fallet R; Odvody J; Burkovetskaya M; Rama Rao KV; Cooper JD; Drack AV; Kielian T Ann Neurol; 2016 Dec; 80(6):909-923. PubMed ID: 27804148 [TBL] [Abstract][Full Text] [Related]
10. Transcript and in silico analysis of CLN3 in juvenile neuronal ceroid lipofuscinosis and associated mouse models. Chan CH; Mitchison HM; Pearce DA Hum Mol Genet; 2008 Nov; 17(21):3332-9. PubMed ID: 18678598 [TBL] [Abstract][Full Text] [Related]
12. Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis. Gomez-Giro G; Arias-Fuenzalida J; Jarazo J; Zeuschner D; Ali M; Possemis N; Bolognin S; Halder R; Jäger C; Kuper WFE; van Hasselt PM; Zaehres H; Del Sol A; van der Putten H; Schöler HR; Schwamborn JC Acta Neuropathol Commun; 2019 Dec; 7(1):222. PubMed ID: 31888773 [TBL] [Abstract][Full Text] [Related]
13. A function retained by the common mutant CLN3 protein is responsible for the late onset of juvenile neuronal ceroid lipofuscinosis. Kitzmüller C; Haines RL; Codlin S; Cutler DF; Mole SE Hum Mol Genet; 2008 Jan; 17(2):303-12. PubMed ID: 17947292 [TBL] [Abstract][Full Text] [Related]
14. Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis. Fossale E; Wolf P; Espinola JA; Lubicz-Nawrocka T; Teed AM; Gao H; Rigamonti D; Cattaneo E; MacDonald ME; Cotman SL BMC Neurosci; 2004 Dec; 5():57. PubMed ID: 15588329 [TBL] [Abstract][Full Text] [Related]
15. Altered sensitivity of cerebellar granule cells to glutamate receptor overactivation in the Cln3(Δex7/8)-knock-in mouse model of juvenile neuronal ceroid lipofuscinosis. Finn R; Kovács AD; Pearce DA Neurochem Int; 2011 May; 58(6):648-55. PubMed ID: 21315126 [TBL] [Abstract][Full Text] [Related]
16. Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons. Parviainen L; Dihanich S; Anderson GW; Wong AM; Brooks HR; Abeti R; Rezaie P; Lalli G; Pope S; Heales SJ; Mitchison HM; Williams BP; Cooper JD Acta Neuropathol Commun; 2017 Oct; 5(1):74. PubMed ID: 29041969 [TBL] [Abstract][Full Text] [Related]
17. Neurodevelopmental delay in the Cln3Deltaex7/8 mouse model for Batten disease. Osório NS; Sampaio-Marques B; Chan CH; Oliveira P; Pearce DA; Sousa N; Rodrigues F Genes Brain Behav; 2009 Apr; 8(3):337-45. PubMed ID: 19243453 [TBL] [Abstract][Full Text] [Related]
18. Age-dependent alterations in neuronal activity in the hippocampus and visual cortex in a mouse model of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3). Burkovetskaya M; Karpuk N; Kielian T Neurobiol Dis; 2017 Apr; 100():19-29. PubMed ID: 28042098 [TBL] [Abstract][Full Text] [Related]
19. Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system. Staropoli JF; Haliw L; Biswas S; Garrett L; Hölter SM; Becker L; Skosyrski S; Da Silva-Buttkus P; Calzada-Wack J; Neff F; Rathkolb B; Rozman J; Schrewe A; Adler T; Puk O; Sun M; Favor J; Racz I; Bekeredjian R; Busch DH; Graw J; Klingenspor M; Klopstock T; Wolf E; Wurst W; Zimmer A; Lopez E; Harati H; Hill E; Krause DS; Guide J; Dragileva E; Gale E; Wheeler VC; Boustany RM; Brown DE; Breton S; Ruether K; Gailus-Durner V; Fuchs H; de Angelis MH; Cotman SL PLoS One; 2012; 7(6):e38310. PubMed ID: 22701626 [TBL] [Abstract][Full Text] [Related]