BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 24737327)

  • 1. Molecular basis of the general base catalysis of an α/β-hydrolase catalytic triad.
    Sun Y; Yin S; Feng Y; Li J; Zhou J; Liu C; Zhu G; Guo Z
    J Biol Chem; 2014 May; 289(22):15867-79. PubMed ID: 24737327
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalytic mechanism of SHCHC synthase in the menaquinone biosynthesis of Escherichia coli: identification and mutational analysis of the active site residues.
    Jiang M; Chen X; Wu XH; Chen M; Wu YD; Guo Z
    Biochemistry; 2009 Jul; 48(29):6921-31. PubMed ID: 19545176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification and characterization of (1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase in the menaquinone biosynthesis of Escherichia coli.
    Jiang M; Chen X; Guo ZF; Cao Y; Chen M; Guo Z
    Biochemistry; 2008 Mar; 47(11):3426-34. PubMed ID: 18284213
    [TBL] [Abstract][Full Text] [Related]  

  • 4. X-ray, NMR, and mutational studies of the catalytic cycle of the GDP-mannose mannosyl hydrolase reaction.
    Gabelli SB; Azurmendi HF; Bianchet MA; Amzel LM; Mildvan AS
    Biochemistry; 2006 Sep; 45(38):11290-303. PubMed ID: 16981689
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structures of E. coli native MenH and two active site mutants.
    Johnston JM; Jiang M; Guo Z; Baker EN
    PLoS One; 2013; 8(4):e61325. PubMed ID: 23637813
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Active site binding and catalytic role of bicarbonate in 1,4-dihydroxy-2-naphthoyl coenzyme A synthases from vitamin K biosynthetic pathways.
    Sun Y; Song H; Li J; Jiang M; Li Y; Zhou J; Guo Z
    Biochemistry; 2012 Jun; 51(22):4580-9. PubMed ID: 22606952
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily.
    Sun Y; Song H; Li J; Li Y; Jiang M; Zhou J; Guo Z
    PLoS One; 2013; 8(4):e63095. PubMed ID: 23658663
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reaction mechanism of hydroxynitrile lyases of the alpha/beta-hydrolase superfamily: the three-dimensional structure of the transient enzyme-substrate complex certifies the crucial role of LYS236.
    Gruber K; Gartler G; Krammer B; Schwab H; Kratky C
    J Biol Chem; 2004 May; 279(19):20501-10. PubMed ID: 14998991
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase.
    Arand M; Wagner H; Oesch F
    J Biol Chem; 1996 Feb; 271(8):4223-9. PubMed ID: 8626766
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Steady-state kinetics and molecular evolution of Escherichia coli MenD [(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase], an anomalous thiamin diphosphate-dependent decarboxylase-carboligase.
    Bhasin M; Billinsky JL; Palmer DR
    Biochemistry; 2003 Nov; 42(46):13496-504. PubMed ID: 14621995
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Charge neutralization in the active site of the catalytic trimer of aspartate transcarbamoylase promotes diverse structural changes.
    Endrizzi JA; Beernink PT
    Protein Sci; 2017 Nov; 26(11):2221-2228. PubMed ID: 28833948
    [TBL] [Abstract][Full Text] [Related]  

  • 12. His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
    Schultz LW; Quirk DJ; Raines RT
    Biochemistry; 1998 Jun; 37(25):8886-98. PubMed ID: 9636030
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.
    Kumar VP; Thomas LM; Bobyk KD; Andi B; Cook PF; West AH
    Biochemistry; 2012 Jan; 51(4):857-66. PubMed ID: 22243403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Exploiting the high-resolution crystal structure of Staphylococcus aureus MenH to gain insight into enzyme activity.
    Dawson A; Fyfe PK; Gillet F; Hunter WN
    BMC Struct Biol; 2011 Apr; 11():19. PubMed ID: 21513522
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Catalytic mechanism of C-C hydrolase MhpC from Escherichia coli: kinetic analysis of His263 and Ser110 site-directed mutants.
    Li C; Montgomery MG; Mohammed F; Li JJ; Wood SP; Bugg TD
    J Mol Biol; 2005 Feb; 346(1):241-51. PubMed ID: 15663941
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stabilization of the second oxyanion intermediate by 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase of the menaquinone pathway: spectroscopic evidence of the involvement of a conserved aspartic acid.
    Chen M; Jiang M; Sun Y; Guo ZF; Guo Z
    Biochemistry; 2011 Jul; 50(26):5893-904. PubMed ID: 21627110
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Two glutamate residues, Glu 208 alpha and Glu 197 beta, are crucial for phosphorylation and dephosphorylation of the active-site histidine residue in succinyl-CoA synthetase.
    Fraser ME; Joyce MA; Ryan DG; Wolodko WT
    Biochemistry; 2002 Jan; 41(2):537-46. PubMed ID: 11781092
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structures of two bacterial 3-hydroxy-3-methylglutaryl-CoA lyases suggest a common catalytic mechanism among a family of TIM barrel metalloenzymes cleaving carbon-carbon bonds.
    Forouhar F; Hussain M; Farid R; Benach J; Abashidze M; Edstrom WC; Vorobiev SM; Xiao R; Acton TB; Fu Z; Kim JJ; Miziorko HM; Montelione GT; Hunt JF
    J Biol Chem; 2006 Mar; 281(11):7533-45. PubMed ID: 16330546
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure and catalysis of acylaminoacyl peptidase: closed and open subunits of a dimer oligopeptidase.
    Harmat V; Domokos K; Menyhárd DK; Palló A; Szeltner Z; Szamosi I; Beke-Somfai T; Náray-Szabó G; Polgár L
    J Biol Chem; 2011 Jan; 286(3):1987-98. PubMed ID: 21084296
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis.
    Dai J; Finci L; Zhang C; Lahiri S; Zhang G; Peisach E; Allen KN; Dunaway-Mariano D
    Biochemistry; 2009 Mar; 48(9):1984-95. PubMed ID: 19154134
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.