BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 24743710)

  • 1. Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid.
    Fischer S; Ronellenfitsch MW; Thiepold AL; Harter PN; Reichert S; Kögel D; Paschke R; Mittelbronn M; Weller M; Steinbach JP; Fulda S; Bähr O
    PLoS One; 2014; 9(4):e94921. PubMed ID: 24743710
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Betulinic acid derivative B10 inhibits glioma cell proliferation through suppression of SIRT1, acetylation of FOXO3a and upregulation of Bim/PUMA.
    Huo L; Bai X; Wang Y; Wang M
    Biomed Pharmacother; 2017 Aug; 92():347-355. PubMed ID: 28554130
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process.
    Gonzalez P; Mader I; Tchoghandjian A; Enzenmüller S; Cristofanon S; Basit F; Debatin KM; Fulda S
    Cell Death Differ; 2012 Aug; 19(8):1337-46. PubMed ID: 22343715
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions.
    Bache M; Zschornak MP; Passin S; Kessler J; Wichmann H; Kappler M; Paschke R; Kaluđerović GN; Kommera H; Taubert H; Vordermark D
    Radiat Oncol; 2011 Sep; 6():111. PubMed ID: 21906280
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.
    Lena A; Rechichi M; Salvetti A; Bartoli B; Vecchio D; Scarcelli V; Amoroso R; Benvenuti L; Gagliardi R; Gremigni V; Rossi L
    J Transl Med; 2009 Feb; 7():13. PubMed ID: 19196452
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells.
    Kanzawa T; Germano IM; Komata T; Ito H; Kondo Y; Kondo S
    Cell Death Differ; 2004 Apr; 11(4):448-57. PubMed ID: 14713959
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death.
    Enzenmüller S; Gonzalez P; Karpel-Massler G; Debatin KM; Fulda S
    Cancer Lett; 2013 Feb; 329(1):27-36. PubMed ID: 23000516
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Betulinic acid derivatives NVX-207 and B10 for treatment of glioblastoma--an in vitro study of cytotoxicity and radiosensitization.
    Bache M; Bernhardt S; Passin S; Wichmann H; Hein A; Zschornak M; Kappler M; Taubert H; Paschke R; Vordermark D
    Int J Mol Sci; 2014 Oct; 15(11):19777-90. PubMed ID: 25361208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protective mechanisms of CA074-me (other than cathepsin-B inhibition) against programmed necrosis induced by global cerebral ischemia/reperfusion injury in rats.
    Xu Y; Wang J; Song X; Wei R; He F; Peng G; Luo B
    Brain Res Bull; 2016 Jan; 120():97-105. PubMed ID: 26562519
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glioma cell death induced by irradiation or alkylating agent chemotherapy is independent of the intrinsic ceramide pathway.
    Gramatzki D; Herrmann C; Happold C; Becker KA; Gulbins E; Weller M; Tabatabai G
    PLoS One; 2013; 8(5):e63527. PubMed ID: 23667632
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of c-Jun N-terminal kinase enhances temozolomide-induced cytotoxicity in human glioma cells.
    Ohba S; Hirose Y; Kawase T; Sano H
    J Neurooncol; 2009 Dec; 95(3):307-316. PubMed ID: 19517066
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Irradiation and hypoxia promote homing of haematopoietic progenitor cells towards gliomas by TGF-beta-dependent HIF-1alpha-mediated induction of CXCL12.
    Tabatabai G; Frank B; Möhle R; Weller M; Wick W
    Brain; 2006 Sep; 129(Pt 9):2426-35. PubMed ID: 16835250
    [TBL] [Abstract][Full Text] [Related]  

  • 13. miR-181b modulates glioma cell sensitivity to temozolomide by targeting MEK1.
    Wang J; Sai K; Chen FR; Chen ZP
    Cancer Chemother Pharmacol; 2013 Jul; 72(1):147-58. PubMed ID: 23645289
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance.
    Ma J; Murphy M; O'Dwyer PJ; Berman E; Reed K; Gallo JM
    Biochem Pharmacol; 2002 Apr; 63(7):1219-28. PubMed ID: 11960598
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypoxia-induced miR-497 decreases glioma cell sensitivity to TMZ by inhibiting apoptosis.
    Lan J; Xue Y; Chen H; Zhao S; Wu Z; Fang J; Han C; Lou M
    FEBS Lett; 2014 Sep; 588(18):3333-9. PubMed ID: 25080009
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A derivative of betulinic acid protects human Retinal Pigment Epithelial (RPE) cells from cobalt chloride-induced acute hypoxic stress.
    Cheng Z; Yao W; Zheng J; Ding W; Wang Y; Zhang T; Zhu L; Zhou F
    Exp Eye Res; 2019 Mar; 180():92-101. PubMed ID: 30578788
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synergistic antitumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model.
    Hanihara M; Kawataki T; Oh-Oka K; Mitsuka K; Nakao A; Kinouchi H
    J Neurosurg; 2016 Jun; 124(6):1594-601. PubMed ID: 26636389
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway.
    Cheng YC; Ding YM; Hueng DY; Chen JY; Chen Y
    J Nutr Biochem; 2016 Jul; 33():63-72. PubMed ID: 27260469
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid.
    Qiu L; Wang Q; Di W; Jiang Q; Schefeller E; Derby S; Wanebo H; Yan B; Wan Y
    Int J Oncol; 2005 Sep; 27(3):823-30. PubMed ID: 16077934
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of the Betulinic Acid-Cisplatin conjugate APC and its precursor DE9B for the treatment of human malignant glioma.
    Bache M; Hein A; Petrenko M; Güttler A; Keßler J; Wichmann H; Kappler M; Emmerich D; Paschke R; Vordermark D
    Chem Biol Interact; 2019 Dec; 314():108841. PubMed ID: 31586452
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.