These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

71 related articles for article (PubMed ID: 24744351)

  • 1. Toxicology. 'Humanized' mouse detects deadly drug side effects.
    Cohen J
    Science; 2014 Apr; 344(6181):244-5. PubMed ID: 24744351
    [No Abstract]   [Full Text] [Related]  

  • 2. Fialuridine induces acute liver failure in chimeric TK-NOG mice: a model for detecting hepatic drug toxicity prior to human testing.
    Xu D; Nishimura T; Nishimura S; Zhang H; Zheng M; Guo YY; Masek M; Michie SA; Glenn J; Peltz G
    PLoS Med; 2014 Apr; 11(4):e1001628. PubMed ID: 24736310
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Generation of humanized liver mouse model by transplant of patient-derived fresh human hepatocytes.
    Kim M; Choi B; Joo SY; Lee H; Lee JH; Lee KW; Lee S; Park JB; Lee SK; Kim SJ
    Transplant Proc; 2014 May; 46(4):1186-90. PubMed ID: 24815156
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chimeric rodents with humanized liver: bridging the preclinical/clinical trial gap in ADME/toxicity studies.
    Foster JR; Lund G; Sapelnikova S; Tyrrell DL; Kneteman NM
    Xenobiotica; 2014 Jan; 44(2):109-22. PubMed ID: 24320885
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatitis B virus limits response of human hepatocytes to interferon-α in chimeric mice.
    Lütgehetmann M; Bornscheuer T; Volz T; Allweiss L; Bockmann JH; Pollok JM; Lohse AW; Petersen J; Dandri M
    Gastroenterology; 2011 Jun; 140(7):2074-83, 2083.e1-2. PubMed ID: 21376046
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Clinical course of four patients receiving the experimental antiviral agent fialuridine for the treatment of chronic hepatitis B infection.
    Stevenson W; Gaffey M; Ishitani M; McCullough C; Dickson R; Caldwell S; Lobo P; Pruett T
    Transplant Proc; 1995 Feb; 27(1):1219-21. PubMed ID: 7878856
    [No Abstract]   [Full Text] [Related]  

  • 7. Can 'humanized' mice improve drug development in the 21st century?
    Peltz G
    Trends Pharmacol Sci; 2013 May; 34(5):255-60. PubMed ID: 23602782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice.
    Suemizu H; Hasegawa M; Kawai K; Taniguchi K; Monnai M; Wakui M; Suematsu M; Ito M; Peltz G; Nakamura M
    Biochem Biophys Res Commun; 2008 Dec; 377(1):248-52. PubMed ID: 18840406
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chimeric mice with humanized liver: tools for the study of drug metabolism, excretion, and toxicity.
    Strom SC; Davila J; Grompe M
    Methods Mol Biol; 2010; 640():491-509. PubMed ID: 20645070
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ultra-rapid cardiotoxicity of the hepatitis C virus protease inhibitor BILN 2061 in the urokinase-type plasminogen activator mouse.
    Vanwolleghem T; Meuleman P; Libbrecht L; Roskams T; De Vos R; Leroux-Roels G
    Gastroenterology; 2007 Oct; 133(4):1144-55. PubMed ID: 17919490
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Humanized animal models to study drug metabolism: no longer a "chimera"?
    Botrè F
    Clin Chem; 2009 Oct; 55(10):1763-4. PubMed ID: 19628657
    [No Abstract]   [Full Text] [Related]  

  • 12. Repopulation of the immunosuppressed retrorsine-treated infant rat liver with human hepatocytes.
    Tachibana A; Tateno C; Yoshizato K
    Xenotransplantation; 2013; 20(4):227-38. PubMed ID: 23683097
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transplantation of engineered chimeric liver with autologous hepatocytes and xenobiotic scaffold.
    Hata T; Uemoto S; Fujimoto Y; Murakami T; Tateno C; Yoshizato K; Kobayashi E
    Ann Surg; 2013 Mar; 257(3):542-7. PubMed ID: 22691372
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity.
    Scheer N; Wilson ID
    Drug Discov Today; 2016 Feb; 21(2):250-63. PubMed ID: 26360054
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera.
    Meuleman P; Libbrecht L; De Vos R; de Hemptinne B; Gevaert K; Vandekerckhove J; Roskams T; Leroux-Roels G
    Hepatology; 2005 Apr; 41(4):847-56. PubMed ID: 15791625
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Perspective of humanized mouse models for assessing PK/PD and toxic profile of drug candidates in preclinical study.
    Chiba K
    Drug Metab Pharmacokinet; 2014; 29(1):1-2. PubMed ID: 24573168
    [No Abstract]   [Full Text] [Related]  

  • 17. Transgenic animals in toxicology.
    Ladiges WC; Ware CB
    Curr Protoc Toxicol; 2001; Chapter 1():Unit1.3. PubMed ID: 23045021
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fialuridine toxicity.
    Schmid R
    Hepatology; 1997 Jun; 25(6):1548. PubMed ID: 9185783
    [No Abstract]   [Full Text] [Related]  

  • 19. Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase.
    Grignet-Debrus C; Cool V; Baudson N; Degrève B; Balzarini J; De Leval L; Debrus S; Velu T; Calberg-Bacq CM
    Cancer Gene Ther; 2000 Feb; 7(2):215-23. PubMed ID: 10770629
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of fialuridine on hepatitis B immune globulin pharmacokinetics following orthotopic liver transplant for chronic hepatitis B viral-induced cirrhosis.
    McGory RW; Ishitani MB; Oliveira WM; Stevenson WC; Dickson RC; Caldwell SH; Pruett TL
    Transplant Proc; 1995 Feb; 27(1):1213-4. PubMed ID: 7878854
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 4.