BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 24746099)

  • 1. Synthesis of a novel UDP-carbasugar as UDP-galactopyranose mutase inhibitor.
    El Bkassiny S; N'Go I; Sevrain CM; Tikad A; Vincent SP
    Org Lett; 2014 May; 16(9):2462-5. PubMed ID: 24746099
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemoenzymatic synthesis, inhibition studies, and X-ray crystallographic analysis of the phosphono analog of UDP-Galp as an inhibitor and mechanistic probe for UDP-galactopyranose mutase.
    Partha SK; Sadeghi-Khomami A; Slowski K; Kotake T; Thomas NR; Jakeman DL; Sanders DA
    J Mol Biol; 2010 Nov; 403(4):578-90. PubMed ID: 20850454
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and inhibition properties of conformational probes for the mutase-catalyzed UDP-galactopyranose/furanose interconversion.
    Caravano A; Mengin-Lecreulx D; Brondello JM; Vincent SP; Sinaÿ P
    Chemistry; 2003 Dec; 9(23):5888-98. PubMed ID: 14673861
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploring the mechanism of binding of UDP-galactopyranose to UDP-galactopyranose mutase by STD-NMR spectroscopy and molecular modeling.
    Yuan Y; Wen X; Sanders DA; Pinto BM
    Biochemistry; 2005 Nov; 44(43):14080-9. PubMed ID: 16245924
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 1,4-Anhydrogalactopyranose is not an intermediate of the mutase catalyzed UDP-galactopyranose/furanose interconversion.
    Caravano A; Sinaÿ P; Vincent SP
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1123-5. PubMed ID: 16377186
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of a carbasugar analogue of a putative intermediate in the UDP-galp-mutase catalyzed isomerization.
    Sadeghi-Khomami A; Blake AJ; Wilson C; Thomas NR
    Org Lett; 2005 Oct; 7(22):4891-4. PubMed ID: 16235915
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Probing UDP-galactopyranose mutase binding pocket: a dramatic effect on substitution of the 6-position of UDP-galactofuranose.
    Eppe G; Peltier P; Daniellou R; Nugier-Chauvin C; Ferrières V; Vincent SP
    Bioorg Med Chem Lett; 2009 Feb; 19(3):814-6. PubMed ID: 19119008
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reversible and efficient inhibition of UDP-galactopyranose mutase by electrophilic, constrained and unsaturated UDP-galactitol analogues.
    Ansiaux C; N'Go I; Vincent SP
    Chemistry; 2012 Nov; 18(46):14860-6. PubMed ID: 23015271
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Convergent and stereoselective synthesis of iminosugar-containing Galf and UDP-Galf mimicks: evaluation as inhibitors of UDP-Gal mutase.
    Liautard V; Desvergnes V; Itoh K; Liu HW; Martin OR
    J Org Chem; 2008 Apr; 73(8):3103-15. PubMed ID: 18358048
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A unique catalytic mechanism for UDP-galactopyranose mutase.
    Soltero-Higgin M; Carlson EE; Gruber TD; Kiessling LL
    Nat Struct Mol Biol; 2004 Jun; 11(6):539-43. PubMed ID: 15133501
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of nonionic substrate mimics of UDP-Galp as candidate inhibitors of UDP galactopyranose mutase (UGM).
    Kuppala R; Borrelli S; Slowski K; Sanders DA; Ravindranathan Kartha KP; Pinto BM
    Bioorg Med Chem Lett; 2015 May; 25(9):1995-7. PubMed ID: 25819094
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Investigation of binding of UDP-Galf and UDP-[3-F]Galf to UDP-galactopyranose mutase by STD-NMR spectroscopy, molecular dynamics, and CORCEMA-ST calculations.
    Yuan Y; Bleile DW; Wen X; Sanders DA; Itoh K; Liu HW; Pinto BM
    J Am Chem Soc; 2008 Mar; 130(10):3157-68. PubMed ID: 18278916
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemical probes of UDP-galactopyranose mutase.
    Carlson EE; May JF; Kiessling LL
    Chem Biol; 2006 Aug; 13(8):825-37. PubMed ID: 16931332
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and analysis of substrate analogues for UDP-galactopyranose mutase: implication for an oxocarbenium ion intermediate in the catalytic mechanism.
    Itoh K; Huang Z; Liu HW
    Org Lett; 2007 Mar; 9(5):879-82. PubMed ID: 17266324
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural basis of substrate binding to UDP-galactopyranose mutase: crystal structures in the reduced and oxidized state complexed with UDP-galactopyranose and UDP.
    Partha SK; van Straaten KE; Sanders DA
    J Mol Biol; 2009 Dec; 394(5):864-77. PubMed ID: 19836401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diastereoselective synthesis of novel iminosugar-containing UDP-Galf mimics: potential inhibitors of UDP-Gal mutase and UDP-Galf transferases.
    Liautard V; Christina AE; Desvergnes V; Martin OR
    J Org Chem; 2006 Sep; 71(19):7337-45. PubMed ID: 16958528
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potent ligands for prokaryotic UDP-galactopyranose mutase that exploit an enzyme subsite.
    Dykhuizen EC; Kiessling LL
    Org Lett; 2009 Jan; 11(1):193-6. PubMed ID: 19067595
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Steric Control of the Rate-Limiting Step of UDP-Galactopyranose Mutase.
    Pierdominici-Sottile G; Cossio-Pérez R; Da Fonseca I; Kizjakina K; Tanner JJ; Sobrado P
    Biochemistry; 2018 Jul; 57(26):3713-3721. PubMed ID: 29757624
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Site-directed mutagenesis of UDP-galactopyranose mutase reveals a critical role for the active-site, conserved arginine residues.
    Chad JM; Sarathy KP; Gruber TD; Addala E; Kiessling LL; Sanders DA
    Biochemistry; 2007 Jun; 46(23):6723-32. PubMed ID: 17511471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Study of Uridine 5'-Diphosphate (UDP)-Galactopyranose Mutase Using UDP-5-Fluorogalactopyranose as a Probe: Incubation Results and Mechanistic Implications.
    Lin GM; Sun HG; Liu HW
    Org Lett; 2016 Jul; 18(14):3438-41. PubMed ID: 27384425
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.