BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 24748654)

  • 1. Ectodomain-specific E-cadherin antibody suppresses skin SCC growth and reduces tumor grade: a multitargeted therapy modulating RTKs and the PTEN-p53-MDM2 axis.
    Brouxhon SM; Kyrkanides S; Raja V; Silberfeld A; Teng X; Trochesset D; Cohen J; Ma L
    Mol Cancer Ther; 2014 Jul; 13(7):1791-802. PubMed ID: 24748654
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling.
    Brouxhon SM; Kyrkanides S; Teng X; Athar M; Ghazizadeh S; Simon M; O'Banion MK; Ma L
    Oncogene; 2014 Jan; 33(2):225-35. PubMed ID: 23318419
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Soluble-E-cadherin activates HER and IAP family members in HER2+ and TNBC human breast cancers.
    Brouxhon SM; Kyrkanides S; Teng X; O'Banion MK; Clarke R; Byers S; Ma L
    Mol Carcinog; 2014 Nov; 53(11):893-906. PubMed ID: 23776059
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways.
    Brouxhon SM; Kyrkanides S; Teng X; Raja V; O'Banion MK; Clarke R; Byers S; Silberfeld A; Tornos C; Ma L
    Clin Cancer Res; 2013 Jun; 19(12):3234-46. PubMed ID: 23620408
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma.
    Worrall C; Suleymanova N; Crudden C; Trocoli Drakensjö I; Candrea E; Nedelcu D; Takahashi SI; Girnita L; Girnita A
    Oncogene; 2017 Jun; 36(23):3274-3286. PubMed ID: 28092675
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The LXR-623-induced long non-coding RNA LINC01125 suppresses the proliferation of breast cancer cells via PTEN/AKT/p53 signaling pathway.
    Wan W; Hou Y; Wang K; Cheng Y; Pu X; Ye X
    Cell Death Dis; 2019 Mar; 10(3):248. PubMed ID: 30867411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice.
    Zheng T; Meng X; Wang J; Chen X; Yin D; Liang Y; Song X; Pan S; Jiang H; Liu L
    J Cell Biochem; 2010 Sep; 111(1):218-28. PubMed ID: 20506484
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Research on miR-126 in glioma targeted regulation of PTEN/PI3K/Akt and MDM2-p53 pathways.
    Chen SR; Cai WP; Dai XJ; Guo AS; Chen HP; Lin GS; Lin RS
    Eur Rev Med Pharmacol Sci; 2019 Apr; 23(8):3461-3470. PubMed ID: 31081101
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway.
    Lv H; Liu R; Fu J; Yang Q; Shi J; Chen P; Ji M; Shi B; Hou P
    Cell Cycle; 2014; 13(18):2962-74. PubMed ID: 25486483
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Could changes in the regulation of the PI3K/PKB/Akt signaling pathway and cell cycle be involved in astrocytic tumor pathogenesis and progression?
    Hlobilkova A; Ehrmann J; Sedlakova E; Krejci V; Knizetova P; Fiuraskova M; Kala M; Kalita O; Kolar Z
    Neoplasma; 2007; 54(4):334-41. PubMed ID: 17822324
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ; Chung TW; Kang SK; Lee YC; Ko JH; Kim JG; Kim CH
    Glycobiology; 2006 Jul; 16(7):573-83. PubMed ID: 16574813
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modulation of RTK by sEcad: a putative mechanism for oncogenicity in oropharyngeal SCCs.
    Teng X; Ma L; Kyrkanides S; Raja V; Trochesset D; Brouxhon SM
    Oral Dis; 2015 Mar; 21(2):185-94. PubMed ID: 24612046
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Temporal PTEN inactivation causes proliferation of saphenous vein smooth muscle cells of human CABG conduits.
    Mitra AK; Jia G; Gangahar DM; Agrawal DK
    J Cell Mol Med; 2009 Jan; 13(1):177-87. PubMed ID: 18363844
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer.
    Herzog A; Bian Y; Vander Broek R; Hall B; Coupar J; Cheng H; Sowers AL; Cook JD; Mitchell JB; Chen Z; Kulkarni AB; Van Waes C
    Clin Cancer Res; 2013 Jul; 19(14):3808-19. PubMed ID: 23640975
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MicroRNA501-5p induces p53 proteasome degradation through the activation of the mTOR/MDM2 pathway in ADPKD cells.
    de Stephanis L; Mangolini A; Servello M; Harris PC; Dell'Atti L; Pinton P; Aguiari G
    J Cell Physiol; 2018 Sep; 233(9):6911-6924. PubMed ID: 29323708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PTEN reconstitution alters glioma responses to c-Met pathway inhibition.
    Goodwin CR; Lal B; Ho S; Woodard CL; Zhou X; Taeger A; Xia S; Laterra J
    Anticancer Drugs; 2011 Oct; 22(9):905-12. PubMed ID: 21654317
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Axl promotes cutaneous squamous cell carcinoma survival through negative regulation of pro-apoptotic Bcl-2 family members.
    Papadakis ES; Cichoń MA; Vyas JJ; Patel N; Ghali L; Cerio R; Storey A; O'Toole EA
    J Invest Dermatol; 2011 Feb; 131(2):509-17. PubMed ID: 21068757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts.
    Lal B; Goodwin CR; Sang Y; Foss CA; Cornet K; Muzamil S; Pomper MG; Kim J; Laterra J
    Mol Cancer Ther; 2009 Jul; 8(7):1751-60. PubMed ID: 19584231
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apoptosis-induced effects of extract from Artemisia annua Linné by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells.
    Kim EJ; Kim GT; Kim BM; Lim EG; Kim SY; Kim YM
    BMC Complement Altern Med; 2017 Apr; 17(1):236. PubMed ID: 28454566
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.