These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

649 related articles for article (PubMed ID: 24750229)

  • 1. Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.
    Highley JR; Kirby J; Jansweijer JA; Webb PS; Hewamadduma CA; Heath PR; Higginbottom A; Raman R; Ferraiuolo L; Cooper-Knock J; McDermott CJ; Wharton SB; Shaw PJ; Ince PG
    Neuropathol Appl Neurobiol; 2014 Oct; 40(6):670-85. PubMed ID: 24750229
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43.
    Koyama A; Sugai A; Kato T; Ishihara T; Shiga A; Toyoshima Y; Koyama M; Konno T; Hirokawa S; Yokoseki A; Nishizawa M; Kakita A; Takahashi H; Onodera O
    Nucleic Acids Res; 2016 Jul; 44(12):5820-36. PubMed ID: 27257061
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.
    Ishihara T; Ariizumi Y; Shiga A; Kato T; Tan CF; Sato T; Miki Y; Yokoo M; Fujino T; Koyama A; Yokoseki A; Nishizawa M; Kakita A; Takahashi H; Onodera O
    Hum Mol Genet; 2013 Oct; 22(20):4136-47. PubMed ID: 23740936
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).
    Volkening K; Leystra-Lantz C; Yang W; Jaffee H; Strong MJ
    Brain Res; 2009 Dec; 1305():168-82. PubMed ID: 19815002
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Downstream Effects of Mutations in
    Dash BP; Freischmidt A; Weishaupt JH; Hermann A
    Int J Mol Sci; 2022 Aug; 23(17):. PubMed ID: 36077049
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Alteration of POLDIP3 splicing associated with loss of function of TDP-43 in tissues affected with ALS.
    Shiga A; Ishihara T; Miyashita A; Kuwabara M; Kato T; Watanabe N; Yamahira A; Kondo C; Yokoseki A; Takahashi M; Kuwano R; Kakita A; Nishizawa M; Takahashi H; Onodera O
    PLoS One; 2012; 7(8):e43120. PubMed ID: 22900096
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
    Fratta P; Sivakumar P; Humphrey J; Lo K; Ricketts T; Oliveira H; Brito-Armas JM; Kalmar B; Ule A; Yu Y; Birsa N; Bodo C; Collins T; Conicella AE; Mejia Maza A; Marrero-Gagliardi A; Stewart M; Mianne J; Corrochano S; Emmett W; Codner G; Groves M; Fukumura R; Gondo Y; Lythgoe M; Pauws E; Peskett E; Stanier P; Teboul L; Hallegger M; Calvo A; Chiò A; Isaacs AM; Fawzi NL; Wang E; Housman DE; Baralle F; Greensmith L; Buratti E; Plagnol V; Fisher EM; Acevedo-Arozena A
    EMBO J; 2018 Jun; 37(11):. PubMed ID: 29764981
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Non-genetically modified models exhibit TARDBP mRNA increase due to perturbed TDP-43 autoregulation.
    Sugai A; Kato T; Koyama A; Koike Y; Konno T; Ishihara T; Onodera O
    Neurobiol Dis; 2019 Oct; 130():104534. PubMed ID: 31310801
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A robust TDP-43 knock-in mouse model of ALS.
    Huang SL; Wu LS; Lee M; Chang CW; Cheng WC; Fang YS; Chen YR; Cheng PL; Shen CJ
    Acta Neuropathol Commun; 2020 Jan; 8(1):3. PubMed ID: 31964415
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration.
    Trist BG; Fifita JA; Hogan A; Grima N; Smith B; Troakes C; Vance C; Shaw C; Al-Sarraj S; Blair IP; Double KL
    Acta Neuropathol Commun; 2022 Aug; 10(1):122. PubMed ID: 36008843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
    Mackenzie IR; Bigio EH; Ince PG; Geser F; Neumann M; Cairns NJ; Kwong LK; Forman MS; Ravits J; Stewart H; Eisen A; McClusky L; Kretzschmar HA; Monoranu CM; Highley JR; Kirby J; Siddique T; Shaw PJ; Lee VM; Trojanowski JQ
    Ann Neurol; 2007 May; 61(5):427-34. PubMed ID: 17469116
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The molecular link between inefficient GluA2 Q/R site-RNA editing and TDP-43 pathology in motor neurons of sporadic amyotrophic lateral sclerosis patients.
    Yamashita T; Kwak S
    Brain Res; 2014 Oct; 1584():28-38. PubMed ID: 24355598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A panel of TDP-43-regulated splicing events verifies loss of TDP-43 function in amyotrophic lateral sclerosis brain tissue.
    Cao MC; Ryan B; Wu J; Curtis MA; Faull RLM; Dragunow M; Scotter EL
    Neurobiol Dis; 2023 Sep; 185():106245. PubMed ID: 37527763
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.
    Gordon D; Dafinca R; Scaber J; Alegre-Abarrategui J; Farrimond L; Scott C; Biggs D; Kent L; Oliver PL; Davies B; Ansorge O; Wade-Martins R; Talbot K
    Neurobiol Dis; 2019 Jan; 121():148-162. PubMed ID: 30290270
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An integrative miRNA-mRNA expression analysis identifies miRNA signatures associated with SOD1 and TARDBP patient-derived motor neurons.
    Dash BP; Freischmidt A; Weishaupt JH; Hermann A
    Hum Mol Genet; 2024 Jul; 33(15):1300-1314. PubMed ID: 38676626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis.
    Tibshirani M; Zhao B; Gentil BJ; Minotti S; Marques C; Keith J; Rogaeva E; Zinman L; Rouaux C; Robertson J; Durham HD
    Hum Mol Genet; 2017 Nov; 26(21):4142-4152. PubMed ID: 28973294
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.
    MacNair L; Xiao S; Miletic D; Ghani M; Julien JP; Keith J; Zinman L; Rogaeva E; Robertson J
    Brain; 2016 Jan; 139(Pt 1):86-100. PubMed ID: 26525917
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Splicing repression is a major function of TDP-43 in motor neurons.
    Donde A; Sun M; Ling JP; Braunstein KE; Pang B; Wen X; Cheng X; Chen L; Wong PC
    Acta Neuropathol; 2019 Nov; 138(5):813-826. PubMed ID: 31332509
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regionally different immunoreactivity for Smurf2 and pSmad2/3 in TDP-43-positive inclusions of amyotrophic lateral sclerosis.
    Nakamura M; Kaneko S; Wate R; Asayama S; Nakamura Y; Fujita K; Ito H; Kusaka H
    Neuropathol Appl Neurobiol; 2013 Feb; 39(2):144-56. PubMed ID: 22435645
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.