These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
243 related articles for article (PubMed ID: 2475246)
1. Inherent resistance of human squamous carcinoma cell lines to methotrexate as a result of decreased polyglutamylation of this drug. Pizzorno G; Chang YM; McGuire JJ; Bertino JR Cancer Res; 1989 Oct; 49(19):5275-80. PubMed ID: 2475246 [TBL] [Abstract][Full Text] [Related]
2. Impaired polyglutamylation of methotrexate as a cause of resistance in CCRF-CEM cells after short-term, high-dose treatment with this drug. Pizzorno G; Mini E; Coronnello M; McGuire JJ; Moroson BA; Cashmore AR; Dreyer RN; Lin JT; Mazzei T; Periti P Cancer Res; 1988 Apr; 48(8):2149-55. PubMed ID: 2450647 [TBL] [Abstract][Full Text] [Related]
3. Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates. Barakat RR; Li WW; Lovelace C; Bertino JR Gynecol Oncol; 1993 Oct; 51(1):54-60. PubMed ID: 7694891 [TBL] [Abstract][Full Text] [Related]
4. Thymidylate synthase as a target for growth inhibition in methotrexate-sensitive and -resistant human head and neck cancer and leukemia cell lines. McGuire JJ; Magee KJ; Russell CA; Canestrari JM Oncol Res; 1997; 9(3):139-47. PubMed ID: 9220499 [TBL] [Abstract][Full Text] [Related]
5. Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells. Chen G; Wright JE; Rosowsky A Mol Pharmacol; 1995 Oct; 48(4):758-65. PubMed ID: 7476904 [TBL] [Abstract][Full Text] [Related]
6. Intrinsic resistance to methotrexate in human soft tissue sarcoma cell lines. Li WW; Lin JT; Schweitzer BI; Tong WP; Niedzwiecki D; Bertino JR Cancer Res; 1992 Jul; 52(14):3908-13. PubMed ID: 1377601 [TBL] [Abstract][Full Text] [Related]
7. N10-propargyl-5,8-dideazafolic acid (CB3717): inhibitory effects on human leukemia cell lines resistant to methotrexate or trimetrexate. Takemura Y; Ohnuma T Mt Sinai J Med; 1992 Oct; 59(5):419-24. PubMed ID: 1435841 [TBL] [Abstract][Full Text] [Related]
8. Determinants of the sensitivity of human small-cell lung cancer cell lines to methotrexate. Curt GA; Jolivet J; Carney DN; Bailey BD; Drake JC; Clendeninn NJ; Chabner BA J Clin Invest; 1985 Oct; 76(4):1323-9. PubMed ID: 2414316 [TBL] [Abstract][Full Text] [Related]
9. Antitumor activity of antifolate inhibitors of thymidylate and purine synthesis in human soft tissue sarcoma cell lines with intrinsic resistance to methotrexate. Li WW; Tong WP; Bertino JR Clin Cancer Res; 1995 Jun; 1(6):631-6. PubMed ID: 9816025 [TBL] [Abstract][Full Text] [Related]
10. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate. Diddens H; Niethammer D; Jackson RC Cancer Res; 1983 Nov; 43(11):5286-92. PubMed ID: 6225514 [TBL] [Abstract][Full Text] [Related]
11. Biochemical and growth inhibitory effects of the erythro and threo isomers of gamma-fluoromethotrexate, a methotrexate analogue defective in polyglutamylation. McGuire JJ; Graber M; Licato N; Vincenz C; Coward JK; Nimec Z; Galivan J Cancer Res; 1989 Aug; 49(16):4517-25. PubMed ID: 2472880 [TBL] [Abstract][Full Text] [Related]
12. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines. van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718 [TBL] [Abstract][Full Text] [Related]
13. Impact of polyglutamation on sensitivity to raltitrexed and methotrexate in relation to drug-induced inhibition of de novo thymidylate and purine biosynthesis in CCRF-CEM cell lines. Barnes MJ; Estlin EJ; Taylor GA; Aherne GW; Hardcastle A; McGuire JJ; Calvete JA; Lunec J; Pearson AD; Newell DR Clin Cancer Res; 1999 Sep; 5(9):2548-58. PubMed ID: 10499632 [TBL] [Abstract][Full Text] [Related]
14. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells. Matherly LH; Barlowe CK; Goldman ID Cancer Res; 1986 Feb; 46(2):588-93. PubMed ID: 2416428 [TBL] [Abstract][Full Text] [Related]
15. Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. Pizzorno G; Moroson BA; Cashmore AR; Russello O; Mayer JR; Galivan J; Bunni MA; Priest DG; Beardsley GP Cancer Res; 1995 Feb; 55(3):566-73. PubMed ID: 7834626 [TBL] [Abstract][Full Text] [Related]
16. Phenotypic heterogeneity in cultured human head and neck squamous cell carcinoma lines with low-level methotrexate resistance. Rosowsky A; Wright JE; Cucchi CA; Lippke JA; Tantravahi R; Ervin TJ; Frei E Cancer Res; 1985 Dec; 45(12 Pt 1):6205-12. PubMed ID: 2415240 [TBL] [Abstract][Full Text] [Related]
17. Mechanisms of sensitivity and natural resistance to antifolates in a methylcholanthrene-induced rat sarcoma. Li WW; Lin JT; Schweitzer BI; Bertino JR Mol Pharmacol; 1991 Nov; 40(5):854-8. PubMed ID: 1719370 [TBL] [Abstract][Full Text] [Related]
18. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells. Rhee MS; Galivan J; Wright JE; Rosowsky A Mol Pharmacol; 1994 Apr; 45(4):783-91. PubMed ID: 7514264 [TBL] [Abstract][Full Text] [Related]
19. Collateral methotrexate resistance in cultured human head and neck carcinoma cells selected for resistance to cis-diamminedichloroplatinum(II). Rosowsky A; Wright JE; Cucchi CA; Flatow JL; Trites DH; Teicher BA; Frei E Cancer Res; 1987 Nov; 47(22):5913-8. PubMed ID: 3664492 [TBL] [Abstract][Full Text] [Related]
20. Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow. Koizumi S; Curt GA; Fine RL; Griffin JD; Chabner BA J Clin Invest; 1985 Mar; 75(3):1008-14. PubMed ID: 2579975 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]