98 related articles for article (PubMed ID: 24752799)
1. Design, synthesis and evaluation of seleno-dihydropyrimidinones as potential multi-targeted therapeutics for Alzheimer's disease.
Canto RF; Barbosa FA; Nascimento V; de Oliveira AS; Brighente IM; Braga AL
Org Biomol Chem; 2014 Jun; 12(21):3470-7. PubMed ID: 24752799
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of dihydropyrimidinone-derived selenoesters as multi-targeted directed compounds against Alzheimer's disease.
Barbosa FAR; Canto RFS; Saba S; Rafique J; Braga AL
Bioorg Med Chem; 2016 Nov; 24(22):5762-5770. PubMed ID: 27681239
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of new 2-benzoxazolinone derivatives as potential cholinesterase inhibitors for therapy of alzheimer's disease.
Szymański P; Janik A; Zurek E; Mikiciuk-Olasik E
Pharmazie; 2011 Jun; 66(6):399-403. PubMed ID: 21699076
[TBL] [Abstract][Full Text] [Related]
4. Novel tacrine analogs as potential cholinesterase inhibitors in Alzheimer's disease.
El-Malah A; Gedawy EM; Kassab AE; Salam RM
Arch Pharm (Weinheim); 2014 Feb; 347(2):96-103. PubMed ID: 24343873
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.
Chao X; He X; Yang Y; Zhou X; Jin M; Liu S; Cheng Z; Liu P; Wang Y; Yu J; Tan Y; Huang Y; Qin J; Rapposelli S; Pi R
Bioorg Med Chem Lett; 2012 Oct; 22(20):6498-502. PubMed ID: 22981331
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and evaluation of novel 4-dimethylamine flavonoid derivatives as potential multi-functional anti-Alzheimer agents.
Luo W; Su YB; Hong C; Tian RG; Su LP; Wang YQ; Li Y; Yue JJ; Wang CJ
Bioorg Med Chem; 2013 Dec; 21(23):7275-82. PubMed ID: 24148835
[TBL] [Abstract][Full Text] [Related]
7. Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
Fang L; Kraus B; Lehmann J; Heilmann J; Zhang Y; Decker M
Bioorg Med Chem Lett; 2008 May; 18(9):2905-9. PubMed ID: 18406135
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
Keri RS; Quintanova C; Marques SM; Esteves AR; Cardoso SM; Santos MA
Bioorg Med Chem; 2013 Aug; 21(15):4559-69. PubMed ID: 23768661
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
Thiratmatrakul S; Yenjai C; Waiwut P; Vajragupta O; Reubroycharoen P; Tohda M; Boonyarat C
Eur J Med Chem; 2014 Mar; 75():21-30. PubMed ID: 24508831
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
Xie SS; Wang XB; Li JY; Yang L; Kong LY
Eur J Med Chem; 2013 Jun; 64():540-53. PubMed ID: 23685572
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease.
Li RS; Wang XB; Hu XJ; Kong LY
Bioorg Med Chem Lett; 2013 May; 23(9):2636-41. PubMed ID: 23511019
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen.
Luo Z; Sheng J; Sun Y; Lu C; Yan J; Liu A; Luo HB; Huang L; Li X
J Med Chem; 2013 Nov; 56(22):9089-99. PubMed ID: 24160297
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
Shan WJ; Huang L; Zhou Q; Meng FC; Li XS
Eur J Med Chem; 2011 Dec; 46(12):5885-93. PubMed ID: 22019228
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and evaluation of 7H-thiazolo-[3,2-b]-1,2,4-triazin-7-one derivatives as dual binding site acetylcholinesterase inhibitors.
Liu S; Shang R; Shi L; Zhou R; He J; Wan DC
Chem Biol Drug Des; 2014 Aug; 84(2):169-74. PubMed ID: 24890706
[TBL] [Abstract][Full Text] [Related]
15. O-Hydroxyl- or o-amino benzylamine-tacrine hybrids: multifunctional biometals chelators, antioxidants, and inhibitors of cholinesterase activity and amyloid-β aggregation.
Mao F; Huang L; Luo Z; Liu A; Lu C; Xie Z; Li X
Bioorg Med Chem; 2012 Oct; 20(19):5884-92. PubMed ID: 22944335
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
[TBL] [Abstract][Full Text] [Related]
17. Current and emerging therapies for Alzheimer's disease.
Nygaard HB
Clin Ther; 2013 Oct; 35(10):1480-9. PubMed ID: 24139420
[TBL] [Abstract][Full Text] [Related]
18. In silico design and search for acetylcholinesterase inhibitors in Alzheimer's disease with a suitable pharmacokinetic profile and low toxicity.
da Silva VB; de Andrade P; Kawano DF; Morais PA; de Almeida JR; Carvalho I; Taft CA; da Silva CH
Future Med Chem; 2011 Jun; 3(8):947-60. PubMed ID: 21707398
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of benzylisoquinoline derivatives as multifunctional agents against Alzheimer's disease.
Xu ZC; Wang XB; Yu WY; Xie SS; Li SY; Kong LY
Bioorg Med Chem Lett; 2014 May; 24(10):2368-73. PubMed ID: 24726809
[TBL] [Abstract][Full Text] [Related]
20. Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds.
Piazzi L; Cavalli A; Colizzi F; Belluti F; Bartolini M; Mancini F; Recanatini M; Andrisano V; Rampa A
Bioorg Med Chem Lett; 2008 Jan; 18(1):423-6. PubMed ID: 17998161
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]