These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 24760140)

  • 1. BH3-only molecule Bim mediates β-cell death in IRS2 deficiency.
    Ren D; Sun J; Mao L; Ye H; Polonsky KS
    Diabetes; 2014 Oct; 63(10):3378-87. PubMed ID: 24760140
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiency.
    Ren D; Sun J; Wang C; Ye H; Mao L; Cheng EH; Bell GI; Polonsky KS
    Diabetes; 2014 Aug; 63(8):2744-50. PubMed ID: 24658302
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity.
    Wali JA; Rondas D; McKenzie MD; Zhao Y; Elkerbout L; Fynch S; Gurzov EN; Akira S; Mathieu C; Kay TW; Overbergh L; Strasser A; Thomas HE
    Cell Death Dis; 2014 Mar; 5(3):e1124. PubMed ID: 24625983
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim.
    Nogueira TC; Paula FM; Villate O; Colli ML; Moura RF; Cunha DA; Marselli L; Marchetti P; Cnop M; Julier C; Eizirik DL
    PLoS Genet; 2013 May; 9(5):e1003532. PubMed ID: 23737756
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
    McKenzie MD; Jamieson E; Jansen ES; Scott CL; Huang DC; Bouillet P; Allison J; Kay TW; Strasser A; Thomas HE
    Diabetes; 2010 Mar; 59(3):644-52. PubMed ID: 19959756
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.
    Ardestani A; Paroni F; Azizi Z; Kaur S; Khobragade V; Yuan T; Frogne T; Tao W; Oberholzer J; Pattou F; Conte JK; Maedler K
    Nat Med; 2014 Apr; 20(4):385-397. PubMed ID: 24633305
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation.
    Barthson J; Germano CM; Moore F; Maida A; Drucker DJ; Marchetti P; Gysemans C; Mathieu C; Nuñez G; Jurisicova A; Eizirik DL; Gurzov EN
    J Biol Chem; 2011 Nov; 286(45):39632-43. PubMed ID: 21937453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.
    Santin I; Moore F; Colli ML; Gurzov EN; Marselli L; Marchetti P; Eizirik DL
    Diabetes; 2011 Dec; 60(12):3279-88. PubMed ID: 21984578
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatocyte growth factor ameliorates hyperglycemia and corrects β-cell mass in IRS2-deficient mice.
    Alvarez-Perez JC; Rosa TC; Casinelli GP; Valle SR; Lakshmipathi J; Rosselot C; Rausell-Palamos F; Vasavada RC; García-Ocaña A
    Mol Endocrinol; 2014 Dec; 28(12):2038-48. PubMed ID: 25361392
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endoplasmic reticulum stress sensitizes pancreatic beta cells to interleukin-1β-induced apoptosis via Bim/A1 imbalance.
    Miani M; Barthson J; Colli ML; Brozzi F; Cnop M; Eizirik DL
    Cell Death Dis; 2013 Jul; 4(7):e701. PubMed ID: 23828564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pseudophosphatase phogrin enables glucose-stimulated insulin signaling in pancreatic β cells.
    Torii S; Kubota C; Saito N; Kawano A; Hou N; Kobayashi M; Torii R; Hosaka M; Kitamura T; Takeuchi T; Gomi H
    J Biol Chem; 2018 Apr; 293(16):5920-5933. PubMed ID: 29483197
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphatase and tensin homolog regulation of islet growth and glucose homeostasis.
    Kushner JA; Simpson L; Wartschow LM; Guo S; Rankin MM; Parsons R; White MF
    J Biol Chem; 2005 Nov; 280(47):39388-93. PubMed ID: 16170201
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insulin receptor substrate-1 and -2 mediate resistance to glucose-induced caspase-3 activation in human neuroblastoma cells.
    Stöhr O; Hahn J; Moll L; Leeser U; Freude S; Bernard C; Schilbach K; Markl A; Udelhoven M; Krone W; Schubert M
    Biochim Biophys Acta; 2011 May; 1812(5):573-80. PubMed ID: 21354306
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.
    Kodama T; Hikita H; Kawaguchi T; Saito Y; Tanaka S; Shigekawa M; Shimizu S; Li W; Miyagi T; Kanto T; Hiramatsu N; Tatsumi T; Takehara T
    J Biol Chem; 2013 Oct; 288(42):30009-30018. PubMed ID: 23986435
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lentivirus shRNA Grb10 targeting the pancreas induces apoptosis and improved glucose tolerance due to decreased plasma glucagon levels.
    Doiron B; Hu W; Norton L; DeFronzo RA
    Diabetologia; 2012 Mar; 55(3):719-28. PubMed ID: 22222503
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.
    Kubota N; Terauchi Y; Tobe K; Yano W; Suzuki R; Ueki K; Takamoto I; Satoh H; Maki T; Kubota T; Moroi M; Okada-Iwabu M; Ezaki O; Nagai R; Ueta Y; Kadowaki T; Noda T
    J Clin Invest; 2004 Oct; 114(7):917-27. PubMed ID: 15467830
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BH3-only protein BIM mediates heat shock-induced apoptosis.
    Mahajan IM; Chen MD; Muro I; Robertson JD; Wright CW; Bratton SB
    PLoS One; 2014; 9(1):e84388. PubMed ID: 24427286
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tungstate promotes β-cell survival in Irs2-/- mice.
    Oliveira JM; Rebuffat SA; Gasa R; Burks DJ; Garcia A; Kalko SG; Zafra D; Guinovart JJ; Gomis R
    Am J Physiol Endocrinol Metab; 2014 Jan; 306(1):E36-47. PubMed ID: 24253047
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protective functions of peroxiredoxin-1 against cytokine-induced MIN6 pancreatic β-cell line death.
    Lee YJ; Song DS; Yoo JS; Hyung KE; Lee MJ; Moon YH; Lee IH; Go BS; Park SY; Hwang KW
    Can J Physiol Pharmacol; 2013 Dec; 91(12):1037-43. PubMed ID: 24289074
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells.
    Kawada Y; Asahara SI; Sugiura Y; Sato A; Furubayashi A; Kawamura M; Bartolome A; Terashi-Suzuki E; Takai T; Kanno A; Koyanagi-Kimura M; Matsuda T; Hashimoto N; Kido Y
    PLoS One; 2017; 12(9):e0184435. PubMed ID: 28886131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.