277 related articles for article (PubMed ID: 24760825)
1. E3 ubiquitin ligase Cullin-5 modulates multiple molecular and cellular responses to heat shock protein 90 inhibition in human cancer cells.
Samant RS; Clarke PA; Workman P
Proc Natl Acad Sci U S A; 2014 May; 111(18):6834-9. PubMed ID: 24760825
[TBL] [Abstract][Full Text] [Related]
2. Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase.
Ehrlich ES; Wang T; Luo K; Xiao Z; Niewiadomska AM; Martinez T; Xu W; Neckers L; Yu XF
Proc Natl Acad Sci U S A; 2009 Dec; 106(48):20330-5. PubMed ID: 19933325
[TBL] [Abstract][Full Text] [Related]
3. Gold nanoparticles loaded with cullin-5 DNA increase sensitivity to 17-AAG in cullin-5 deficient breast cancer cells.
Talamantez-Lyburn S; Brown P; Hondrogiannis N; Ratliff J; Wicks SL; Nana N; Zheng Z; Rosenzweig Z; Hondrogiannis E; Devadas MS; Ehrlich ES
Int J Pharm; 2019 Jun; 564():281-292. PubMed ID: 30999048
[TBL] [Abstract][Full Text] [Related]
4. Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery.
Ding G; Chen P; Zhang H; Huang X; Zang Y; Li J; Li J; Wong J
J Biol Chem; 2016 Sep; 291(38):20125-35. PubMed ID: 27489107
[TBL] [Abstract][Full Text] [Related]
5. Silencing of HSP90 cochaperone AHA1 expression decreases client protein activation and increases cellular sensitivity to the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
Holmes JL; Sharp SY; Hobbs S; Workman P
Cancer Res; 2008 Feb; 68(4):1188-97. PubMed ID: 18281495
[TBL] [Abstract][Full Text] [Related]
6. Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation.
Krishnamoorthy GP; Guida T; Alfano L; Avilla E; Santoro M; Carlomagno F; Melillo RM
J Biol Chem; 2013 Jun; 288(24):17481-94. PubMed ID: 23629654
[TBL] [Abstract][Full Text] [Related]
7. Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression.
Schulz R; Marchenko ND; Holembowski L; Fingerle-Rowson G; Pesic M; Zender L; Dobbelstein M; Moll UM
J Exp Med; 2012 Feb; 209(2):275-89. PubMed ID: 22271573
[TBL] [Abstract][Full Text] [Related]
8. HECTD3 Mediates an HSP90-Dependent Degradation Pathway for Protein Kinase Clients.
Li Z; Zhou L; Prodromou C; Savic V; Pearl LH
Cell Rep; 2017 Jun; 19(12):2515-2528. PubMed ID: 28636940
[TBL] [Abstract][Full Text] [Related]
9. CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.
Kostrhon S; Prabu JR; Baek K; Horn-Ghetko D; von Gronau S; Klügel M; Basquin J; Alpi AF; Schulman BA
Nat Chem Biol; 2021 Oct; 17(10):1075-1083. PubMed ID: 34518685
[TBL] [Abstract][Full Text] [Related]
10. Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors.
Smith JR; Clarke PA; de Billy E; Workman P
Oncogene; 2009 Jan; 28(2):157-69. PubMed ID: 18931700
[TBL] [Abstract][Full Text] [Related]
11. Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.
Prince TL; Kijima T; Tatokoro M; Lee S; Tsutsumi S; Yim K; Rivas C; Alarcon S; Schwartz H; Khamit-Kush K; Scroggins BT; Beebe K; Trepel JB; Neckers L
PLoS One; 2015; 10(10):e0141786. PubMed ID: 26517842
[TBL] [Abstract][Full Text] [Related]
12. Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).
Bulatov E; Martin EM; Chatterjee S; Knebel A; Shimamura S; Konijnenberg A; Johnson C; Zinn N; Grandi P; Sobott F; Ciulli A
J Biol Chem; 2015 Feb; 290(7):4178-91. PubMed ID: 25505247
[TBL] [Abstract][Full Text] [Related]
13. ErbB2 degradation mediated by the co-chaperone protein CHIP.
Zhou P; Fernandes N; Dodge IL; Reddi AL; Rao N; Safran H; DiPetrillo TA; Wazer DE; Band V; Band H
J Biol Chem; 2003 Apr; 278(16):13829-37. PubMed ID: 12574167
[TBL] [Abstract][Full Text] [Related]
14. Functional inactivation of endogenous MDM2 and CHIP by HSP90 causes aberrant stabilization of mutant p53 in human cancer cells.
Li D; Marchenko ND; Schulz R; Fischer V; Velasco-Hernandez T; Talos F; Moll UM
Mol Cancer Res; 2011 May; 9(5):577-88. PubMed ID: 21478269
[TBL] [Abstract][Full Text] [Related]
15. Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding.
Fearns C; Pan Q; Mathison JC; Chuang TH
J Biol Chem; 2006 Nov; 281(45):34592-600. PubMed ID: 16968706
[TBL] [Abstract][Full Text] [Related]
16. HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells.
Rao R; Fiskus W; Yang Y; Lee P; Joshi R; Fernandez P; Mandawat A; Atadja P; Bradner JE; Bhalla K
Blood; 2008 Sep; 112(5):1886-93. PubMed ID: 18591380
[TBL] [Abstract][Full Text] [Related]
17. Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells.
Blessing NA; Kasturirangan S; Zink EM; Schroyer AL; Chadee DN
Cell Signal; 2017 Nov; 39():66-73. PubMed ID: 28757353
[TBL] [Abstract][Full Text] [Related]
18. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.
Mahrour N; Redwine WB; Florens L; Swanson SK; Martin-Brown S; Bradford WD; Staehling-Hampton K; Washburn MP; Conaway RC; Conaway JW
J Biol Chem; 2008 Mar; 283(12):8005-13. PubMed ID: 18187417
[TBL] [Abstract][Full Text] [Related]
19. UBR1 promotes protein kinase quality control and sensitizes cells to Hsp90 inhibition.
Sultana R; Theodoraki MA; Caplan AJ
Exp Cell Res; 2012 Jan; 318(1):53-60. PubMed ID: 21983172
[TBL] [Abstract][Full Text] [Related]
20. Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes.
Yu Q; Hu Z; Shen Y; Jiang Y; Pan P; Hou T; Pan ZQ; Huang J; Sun Y
Neoplasia; 2020 Apr; 22(4):179-191. PubMed ID: 32145688
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]