BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

456 related articles for article (PubMed ID: 24762947)

  • 1. Design of multi-target compounds as AChE, BACE1, and amyloid-β(1-42) oligomerization inhibitors: in silico and in vitro studies.
    Hernández-Rodríguez M; Correa-Basurto J; Martínez-Ramos F; Padilla-Martínez II; Benítez-Cardoza CG; Mera-Jiménez E; Rosales-Hernández MC
    J Alzheimers Dis; 2014; 41(4):1073-85. PubMed ID: 24762947
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, Aβ aggregation, and β-secretase.
    Sun Q; Peng DY; Yang SG; Zhu XL; Yang WC; Yang GF
    Bioorg Med Chem; 2014 Sep; 22(17):4784-91. PubMed ID: 25088549
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
    Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AβPP-β Cleavage Decreasing Amyloid-β Production and Accumulation in Alzheimer's Disease Models.
    Resende R; Ferreira-Marques M; Moreira P; Coimbra JRM; Baptista SJ; Isidoro C; Salvador JAR; Dinis TCP; Pereira CF; Santos AE
    J Alzheimers Dis; 2020; 76(4):1317-1337. PubMed ID: 32597812
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Flavanone glycosides inhibit β-site amyloid precursor protein cleaving enzyme 1 and cholinesterase and reduce Aβ aggregation in the amyloidogenic pathway.
    Ali MY; Jannat S; Edraki N; Das S; Chang WK; Kim HC; Park SK; Chang MS
    Chem Biol Interact; 2019 Aug; 309():108707. PubMed ID: 31194956
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Benzophenone-based derivatives: a novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
    Belluti F; Bartolini M; Bottegoni G; Bisi A; Cavalli A; Andrisano V; Rampa A
    Eur J Med Chem; 2011 May; 46(5):1682-93. PubMed ID: 21397996
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sarsasapogenin: A steroidal saponin from Asparagus racemosus as multi target directed ligand in Alzheimer's disease.
    Kashyap P; Muthusamy K; Niranjan M; Trikha S; Kumar S
    Steroids; 2020 Jan; 153():108529. PubMed ID: 31672628
    [TBL] [Abstract][Full Text] [Related]  

  • 8. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
    Meredith JE; Thompson LA; Toyn JH; Marcin L; Barten DM; Marcinkeviciene J; Kopcho L; Kim Y; Lin A; Guss V; Burton C; Iben L; Polson C; Cantone J; Ford M; Drexler D; Fiedler T; Lentz KA; Grace JE; Kolb J; Corsa J; Pierdomenico M; Jones K; Olson RE; Macor JE; Albright CF
    J Pharmacol Exp Ther; 2008 Aug; 326(2):502-13. PubMed ID: 18499745
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Zha GF; Zhang CP; Qin HL; Jantan I; Sher M; Amjad MW; Hussain MA; Hussain Z; Bukhari SN
    Bioorg Med Chem; 2016 May; 24(10):2352-9. PubMed ID: 27083471
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetics and molecular docking of dihydroxanthyletin-type coumarins from Angelica decursiva that inhibit cholinesterase and BACE1.
    Ali MY; Seong SH; Jung HA; Jannat S; Choi JS
    Arch Pharm Res; 2018 Jul; 41(7):753-764. PubMed ID: 30047040
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.
    Catto M; Berezin AA; Lo Re D; Loizou G; Demetriades M; De Stradis A; Campagna F; Koutentis PA; Carotti A
    Eur J Med Chem; 2012 Dec; 58():84-97. PubMed ID: 23108363
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z; Qiang X; Li Y; Yuan W; Liu Q; Shi Y; Ang W; Luo Y; Tan Z; Deng Y
    Eur J Med Chem; 2015 Apr; 94():348-66. PubMed ID: 25778991
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation.
    Panek D; Więckowska A; Wichur T; Bajda M; Godyń J; Jończyk J; Mika K; Janockova J; Soukup O; Knez D; Korabecny J; Gobec S; Malawska B
    Eur J Med Chem; 2017 Jan; 125():676-695. PubMed ID: 27721153
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multifunctional novel Diallyl disulfide (DADS) derivatives with β-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.
    Manral A; Saini V; Meena P; Tiwari M
    Bioorg Med Chem; 2015 Oct; 23(19):6389-403. PubMed ID: 26337018
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rosuvastatin ameliorates cognitive impairment in rats fed with high-salt and cholesterol diet via inhibiting acetylcholinesterase activity and amyloid beta peptide aggregation.
    Husain I; Akhtar M; Abdin MZ; Islamuddin M; Shaharyar M; Najmi AK
    Hum Exp Toxicol; 2018 Apr; 37(4):399-411. PubMed ID: 28441890
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and evaluation of multi-target-directed ligands for the treatment of Alzheimer's disease based on the fusion of donepezil and melatonin.
    Wang J; Wang ZM; Li XM; Li F; Wu JJ; Kong LY; Wang XB
    Bioorg Med Chem; 2016 Sep; 24(18):4324-4338. PubMed ID: 27460699
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
    Maqbool M; Manral A; Jameel E; Kumar J; Saini V; Shandilya A; Tiwari M; Hoda N; Jayaram B
    Bioorg Med Chem; 2016 Jun; 24(12):2777-88. PubMed ID: 27157006
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of galantamine on β-amyloid release and beta-site cleaving enzyme 1 expression in differentiated human neuroblastoma SH-SY5Y cells.
    Li Q; Wu D; Zhang L; Zhang Y
    Exp Gerontol; 2010 Nov; 45(11):842-7. PubMed ID: 20600777
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones.
    Lee S; Youn K; Lim G; Lee J; Jun M
    Molecules; 2018 Jun; 23(7):. PubMed ID: 29932100
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibitory activities of major anthraquinones and other constituents from Cassia obtusifolia against β-secretase and cholinesterases.
    Jung HA; Ali MY; Jung HJ; Jeong HO; Chung HY; Choi JS
    J Ethnopharmacol; 2016 Sep; 191():152-160. PubMed ID: 27321278
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.