BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 24766364)

  • 1. Computational analysis of benzofuran-2-carboxlic acids as potent Pim-1 kinase inhibitors.
    Wadood A; Jamal SB; Riaz M; Mir A
    Pharm Biol; 2014 Sep; 52(9):1170-8. PubMed ID: 24766364
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors.
    Xiang Y; Hirth B; Asmussen G; Biemann HP; Bishop KA; Good A; Fitzgerald M; Gladysheva T; Jain A; Jancsics K; Liu J; Metz M; Papoulis A; Skerlj R; Stepp JD; Wei RR
    Bioorg Med Chem Lett; 2011 May; 21(10):3050-6. PubMed ID: 21507633
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting Pim kinases for cancer treatment: opportunities and challenges.
    Le BT; Kumarasiri M; Adams JR; Yu M; Milne R; Sykes MJ; Wang S
    Future Med Chem; 2015; 7(1):35-53. PubMed ID: 25582332
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.
    Wang HL; Cee VJ; Chavez F; Lanman BA; Reed AB; Wu B; Guerrero N; Lipford JR; Sastri C; Winston J; Andrews KL; Huang X; Lee MR; Mohr C; Xu Y; Zhou Y; Tasker AS
    Bioorg Med Chem Lett; 2015 Feb; 25(4):834-40. PubMed ID: 25597005
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase.
    Pierce AC; Jacobs M; Stuver-Moody C
    J Med Chem; 2008 Mar; 51(6):1972-5. PubMed ID: 18290603
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases.
    Casuscelli F; Ardini E; Avanzi N; Casale E; Cervi G; D'Anello M; Donati D; Faiardi D; Ferguson RD; Fogliatto G; Galvani A; Marsiglio A; Mirizzi DG; Montemartini M; Orrenius C; Papeo G; Piutti C; Salom B; Felder ER
    Bioorg Med Chem; 2013 Dec; 21(23):7364-80. PubMed ID: 24139169
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold.
    Nishiguchi GA; Burger MT; Han W; Lan J; Atallah G; Tamez V; Lindvall M; Bellamacina C; Garcia P; Feucht P; Zavorotinskaya T; Dai Y; Wong K
    Bioorg Med Chem Lett; 2016 May; 26(9):2328-32. PubMed ID: 26995528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of novel inhibitors for Pim-1 kinase using pharmacophore modeling based on a novel method for selecting pharmacophore generation subsets.
    Shahin R; Swellmeen L; Shaheen O; Aboalhaija N; Habash M
    J Comput Aided Mol Des; 2016 Jan; 30(1):39-68. PubMed ID: 26685860
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Rational Design of a Potent Pan-Pim Kinases Inhibitor with a Rhodanine-Benzoimidazole Structure.
    Sawaguchi Y; Yamazaki R; Nishiyama Y; Sasai T; Mae M; Abe A; Yaegashi T; Nishiyama H; Matsuzaki T
    Anticancer Res; 2017 Aug; 37(8):4051-4057. PubMed ID: 28739687
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Integrated molecular docking, 3D QSAR and molecular dynamics simulation studies on indole derivatives for designing new Pim-1 inhibitors.
    Peddi SR; Peddi SR; Sivan S; Veerati R; Manga V
    J Recept Signal Transduct Res; 2020 Feb; 40(1):1-14. PubMed ID: 31931654
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure based drug design of Pim-1 kinase followed by pharmacophore guided synthesis of quinolone-based inhibitors.
    Swellmeen L; Shahin R; Al-Hiari Y; Alamiri A; Hasan A; Shaheen O
    Bioorg Med Chem; 2017 Sep; 25(17):4855-4875. PubMed ID: 28760531
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases.
    Dao VH; Ourliac-Garnier I; Logé C; McCarthy FO; Bach S; da Silva TG; Denevault-Sabourin C; Thiéfaine J; Baratte B; Robert T; Gouilleux F; Brachet-Botineau M; Bazin MA; Marchand P
    Molecules; 2021 Oct; 26(21):. PubMed ID: 34770981
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitors.
    Mori M; Tintori C; Christopher RS; Radi M; Schenone S; Musumeci F; Brullo C; Sanità P; Delle Monache S; Angelucci A; Kissova M; Crespan E; Maga G; Botta M
    ChemMedChem; 2013 Mar; 8(3):484-96. PubMed ID: 23436791
    [TBL] [Abstract][Full Text] [Related]  

  • 14. New Mechanistic Insight on the PIM-1 Kinase Inhibitor AZD1208 Using Multidrug Resistant Human Erythroleukemia Cell Lines and Molecular Docking Simulations.
    Marques MB; González-Durruthy M; da Silva Nornberg BF; Oliveira BR; Almeida DV; de Souza Votto AP; Marins LF
    Curr Top Med Chem; 2019; 19(11):914-926. PubMed ID: 31072293
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thiazolidine derivatives as potent and selective inhibitors of the PIM kinase family.
    Bataille CJ; Brennan MB; Byrne S; Davies SG; Durbin M; Fedorov O; Huber KV; Jones AM; Knapp S; Liu G; Nadali A; Quevedo CE; Russell AJ; Walker RG; Westwood R; Wynne GM
    Bioorg Med Chem; 2017 May; 25(9):2657-2665. PubMed ID: 28341403
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting Pim-1 kinase for potential drug-development.
    Gadewal N; Varma A
    Int J Comput Biol Drug Des; 2012; 5(2):137-51. PubMed ID: 22854122
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-based design of low-nanomolar PIM kinase inhibitors.
    Ishchenko A; Zhang L; Le Brazidec JY; Fan J; Chong JH; Hingway A; Raditsis A; Singh L; Elenbaas B; Hong VS; Marcotte D; Silvian L; Enyedy I; Chao J
    Bioorg Med Chem Lett; 2015 Feb; 25(3):474-80. PubMed ID: 25575657
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase.
    Holder S; Lilly M; Brown ML
    Bioorg Med Chem; 2007 Oct; 15(19):6463-73. PubMed ID: 17637507
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of pyrrolo[2,3-g]indazoles as new Pim kinase inhibitors.
    Gavara L; Suchaud V; Nauton L; Théry V; Anizon F; Moreau P
    Bioorg Med Chem Lett; 2013 Apr; 23(8):2298-301. PubMed ID: 23499503
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and structure-activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinase.
    Sliman F; Blairvacq M; Durieu E; Meijer L; Rodrigo J; Desmaële D
    Bioorg Med Chem Lett; 2010 May; 20(9):2801-5. PubMed ID: 20363627
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.