BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 24766810)

  • 1. CLP1 founder mutation links tRNA splicing and maturation to cerebellar development and neurodegeneration.
    Schaffer AE; Eggens VR; Caglayan AO; Reuter MS; Scott E; Coufal NG; Silhavy JL; Xue Y; Kayserili H; Yasuno K; Rosti RO; Abdellateef M; Caglar C; Kasher PR; Cazemier JL; Weterman MA; Cantagrel V; Cai N; Zweier C; Altunoglu U; Satkin NB; Aktar F; Tuysuz B; Yalcinkaya C; Caksen H; Bilguvar K; Fu XD; Trotta CR; Gabriel S; Reis A; Gunel M; Baas F; Gleeson JG
    Cell; 2014 Apr; 157(3):651-63. PubMed ID: 24766810
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The
    Monaghan CE; Adamson SI; Kapur M; Chuang JH; Ackerman SL
    Proc Natl Acad Sci U S A; 2021 Sep; 118(39):. PubMed ID: 34548404
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modeling a human CLP1 mutation in mouse identifies an accumulation of tyrosine pre-tRNA fragments causing pontocerebellar hypoplasia type 10.
    Morisaki I; Shiraishi H; Fujinami H; Shimizu N; Hikida T; Arai Y; Kobayashi T; Hanada R; Penninger JM; Fujiki M; Hanada T
    Biochem Biophys Res Commun; 2021 Sep; 570():60-66. PubMed ID: 34273619
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human RNA 5'-kinase (hClp1) can function as a tRNA splicing enzyme in vivo.
    Ramirez A; Shuman S; Schwer B
    RNA; 2008 Sep; 14(9):1737-45. PubMed ID: 18648070
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.
    Karaca E; Weitzer S; Pehlivan D; Shiraishi H; Gogakos T; Hanada T; Jhangiani SN; Wiszniewski W; Withers M; Campbell IM; Erdin S; Isikay S; Franco LM; Gonzaga-Jauregui C; Gambin T; Gelowani V; Hunter JV; Yesil G; Koparir E; Yilmaz S; Brown M; Briskin D; Hafner M; Morozov P; Farazi TA; Bernreuther C; Glatzel M; Trattnig S; Friske J; Kronnerwetter C; Bainbridge MN; Gezdirici A; Seven M; Muzny DM; Boerwinkle E; Ozen M; ; Clausen T; Tuschl T; Yuksel A; Hess A; Gibbs RA; Martinez J; Penninger JM; Lupski JR
    Cell; 2014 Apr; 157(3):636-50. PubMed ID: 24766809
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage.
    Hayne CK; Schmidt CA; Haque MI; Matera AG; Stanley RE
    Nucleic Acids Res; 2020 Aug; 48(14):7609-7622. PubMed ID: 32476018
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CLP1 as a novel player in linking tRNA splicing to neurodegenerative disorders.
    Weitzer S; Hanada T; Penninger JM; Martinez J
    Wiley Interdiscip Rev RNA; 2015; 6(1):47-63. PubMed ID: 25142875
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.
    Sekulovski S; Devant P; Panizza S; Gogakos T; Pitiriciu A; Heitmeier K; Ramsay EP; Barth M; Schmidt C; Tuschl T; Baas F; Weitzer S; Martinez J; Trowitzsch S
    Nat Commun; 2021 Sep; 12(1):5610. PubMed ID: 34584079
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 2 new cases of pontocerebellar hypoplasia type 10 identified by whole exome sequencing in a Turkish family.
    Wafik M; Taylor J; Lester T; Gibbons RJ; Shears DJ
    Eur J Med Genet; 2018 May; 61(5):273-279. PubMed ID: 29307788
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent insights into the structure, function, and regulation of the eukaryotic transfer RNA splicing endonuclease complex.
    Hayne CK; Lewis TA; Stanley RE
    Wiley Interdiscip Rev RNA; 2022 Sep; 13(5):e1717. PubMed ID: 35156311
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components.
    Mair B; Popow J; Mechtler K; Weitzer S; Martinez J
    Biochem Soc Trans; 2013 Aug; 41(4):831-7. PubMed ID: 23863140
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN.
    Sekulovski S; Sušac L; Stelzl LS; Tampé R; Trowitzsch S
    Nat Struct Mol Biol; 2023 Jun; 30(6):834-840. PubMed ID: 37231152
    [TBL] [Abstract][Full Text] [Related]  

  • 13. What connects splicing of transfer RNA precursor molecules with pontocerebellar hypoplasia?
    Sekulovski S; Trowitzsch S
    Bioessays; 2023 Feb; 45(2):e2200130. PubMed ID: 36517085
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia.
    Schmidt CA; Min LY; McVay MH; Giusto JD; Brown JC; Salzler HR; Matera AG
    Biol Open; 2022 Mar; 11(3):. PubMed ID: 35132432
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CLP1 acts as the main RNA kinase in mice.
    Fujinami H; Shiraishi H; Hada K; Inoue M; Morisaki I; Higa R; Shin T; Kobayashi T; Hanada R; Penninger JM; Mimata H; Hanada T
    Biochem Biophys Res Commun; 2020 Feb; ():. PubMed ID: 32081435
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs.
    Weitzer S; Martinez J
    Nature; 2007 May; 447(7141):222-6. PubMed ID: 17495927
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Function of yeast and amphioxus tRNA ligase in IRE1alpha-dependent XBP1 mRNA splicing.
    Iwawaki T; Tokuda M
    Biochem Biophys Res Commun; 2011 Oct; 413(4):527-31. PubMed ID: 21924241
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ZNHIT3 is defective in PEHO syndrome, a severe encephalopathy with cerebellar granule neuron loss.
    Anttonen AK; Laari A; Kousi M; Yang YJ; Jääskeläinen T; Somer M; Siintola E; Jakkula E; Muona M; Tegelberg S; Lönnqvist T; Pihko H; Valanne L; Paetau A; Lun MP; Hästbacka J; Kopra O; Joensuu T; Katsanis N; Lehtinen MK; Palvimo JJ; Lehesjoki AE
    Brain; 2017 May; 140(5):1267-1279. PubMed ID: 28335020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytoplasmic splicing of tRNA in Saccharomyces cerevisiae.
    Yoshihisa T; Ohshima C; Yunoki-Esaki K; Endo T
    Genes Cells; 2007 Mar; 12(3):285-97. PubMed ID: 17352735
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Arabidopsis CLP1-SIMILAR PROTEIN3, an ortholog of human polyadenylation factor CLP1, functions in gametophyte, embryo, and postembryonic development.
    Xing D; Zhao H; Li QQ
    Plant Physiol; 2008 Dec; 148(4):2059-69. PubMed ID: 18971429
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.