302 related articles for article (PubMed ID: 24778222)
1. PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
Eren M; Boe AE; Murphy SB; Place AT; Nagpal V; Morales-Nebreda L; Urich D; Quaggin SE; Budinger GR; Mutlu GM; Miyata T; Vaughan DE
Proc Natl Acad Sci U S A; 2014 May; 111(19):7090-5. PubMed ID: 24778222
[TBL] [Abstract][Full Text] [Related]
2. Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice.
Sato S; Kawamata Y; Takahashi A; Imai Y; Hanyu A; Okuma A; Takasugi M; Yamakoshi K; Sorimachi H; Kanda H; Ishikawa Y; Sone S; Nishioka Y; Ohtani N; Hara E
Nat Commun; 2015 Apr; 6():7035. PubMed ID: 25923845
[TBL] [Abstract][Full Text] [Related]
3. Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, "Klotho" mouse.
Takeshita K; Yamamoto K; Ito M; Kondo T; Matsushita T; Hirai M; Kojima T; Nishimura M; Nabeshima Y; Loskutoff DJ; Saito H; Murohara T
Semin Thromb Hemost; 2002 Dec; 28(6):545-54. PubMed ID: 12536348
[TBL] [Abstract][Full Text] [Related]
4. SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence.
Wan YZ; Gao P; Zhou S; Zhang ZQ; Hao DL; Lian LS; Li YJ; Chen HZ; Liu DP
Aging Cell; 2014 Oct; 13(5):890-9. PubMed ID: 25040736
[TBL] [Abstract][Full Text] [Related]
5. Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence.
Boe AE; Eren M; Murphy SB; Kamide CE; Ichimura A; Terry D; McAnally D; Smith LH; Miyata T; Vaughan DE
Circulation; 2013 Nov; 128(21):2318-24. PubMed ID: 24092817
[TBL] [Abstract][Full Text] [Related]
6. PAI-1 Regulation of TGF-β1-induced Alveolar Type II Cell Senescence, SASP Secretion, and SASP-mediated Activation of Alveolar Macrophages.
Rana T; Jiang C; Liu G; Miyata T; Antony V; Thannickal VJ; Liu RM
Am J Respir Cell Mol Biol; 2020 Mar; 62(3):319-330. PubMed ID: 31513752
[TBL] [Abstract][Full Text] [Related]
7. Glucose Oxidase Induces Cellular Senescence in Immortal Renal Cells through ILK by Downregulating Klotho Gene Expression.
Troyano-Suárez N; del Nogal-Avila M; Mora I; Sosa P; López-Ongil S; Rodriguez-Puyol D; Olmos G; Ruíz-Torres MP
Oxid Med Cell Longev; 2015; 2015():416738. PubMed ID: 26583057
[TBL] [Abstract][Full Text] [Related]
8. Klotho ablation converts the biochemical and skeletal alterations in FGF23 (R176Q) transgenic mice to a Klotho-deficient phenotype.
Bai X; Dinghong Q; Miao D; Goltzman D; Karaplis AC
Am J Physiol Endocrinol Metab; 2009 Jan; 296(1):E79-88. PubMed ID: 18984852
[TBL] [Abstract][Full Text] [Related]
9. Thymic Epithelial Cell Support of Thymopoiesis Does Not Require
Xing Y; Smith MJ; Goetz CA; McElmurry RT; Parker SL; Min D; Hollander GA; Weinberg KI; Tolar J; Stefanski HE; Blazar BR
J Immunol; 2018 Dec; 201(11):3320-3328. PubMed ID: 30373854
[TBL] [Abstract][Full Text] [Related]
10. A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence.
Ghosh AK; Rai R; Park KE; Eren M; Miyata T; Wilsbacher LD; Vaughan DE
Oncotarget; 2016 Nov; 7(45):72443-72457. PubMed ID: 27736799
[TBL] [Abstract][Full Text] [Related]
11. Role of plasminogen activator inhibitor-1 in senescence and aging.
Eren M; Boe AE; Klyachko EA; Vaughan DE
Semin Thromb Hemost; 2014 Sep; 40(6):645-51. PubMed ID: 25173500
[TBL] [Abstract][Full Text] [Related]
12. Relationship of the bone phenotype of the Klotho mutant mouse model of accelerated aging to changes in skeletal architecture that occur with chronological aging.
Verlinden L; Li S; Veldurthy V; Carmeliet G; Christakos S
Front Endocrinol (Lausanne); 2024; 15():1310466. PubMed ID: 38352710
[TBL] [Abstract][Full Text] [Related]
13. Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence.
Vaughan DE; Rai R; Khan SS; Eren M; Ghosh AK
Arterioscler Thromb Vasc Biol; 2017 Aug; 37(8):1446-1452. PubMed ID: 28572158
[TBL] [Abstract][Full Text] [Related]
14. The goddess who spins the thread of life: Klotho, psychiatric stress, and accelerated aging.
Wolf EJ; Morrison FG; Sullivan DR; Logue MW; Guetta RE; Stone A; Schichman SA; McGlinchey RE; Milberg WP; Miller MW
Brain Behav Immun; 2019 Aug; 80():193-203. PubMed ID: 30872092
[TBL] [Abstract][Full Text] [Related]
15. The secreted Klotho protein restores phosphate retention and suppresses accelerated aging in Klotho mutant mice.
Chen TH; Kuro-O M; Chen CH; Sue YM; Chen YC; Wu HH; Cheng CY
Eur J Pharmacol; 2013 Jan; 698(1-3):67-73. PubMed ID: 23041151
[TBL] [Abstract][Full Text] [Related]
16. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.
Kortlever RM; Higgins PJ; Bernards R
Nat Cell Biol; 2006 Aug; 8(8):877-84. PubMed ID: 16862142
[TBL] [Abstract][Full Text] [Related]
17. PAI-1 contributes to homocysteine-induced cellular senescence.
Sun T; Ghosh AK; Eren M; Miyata T; Vaughan DE
Cell Signal; 2019 Dec; 64():109394. PubMed ID: 31472244
[TBL] [Abstract][Full Text] [Related]
18. Bicarbonate-sensitive calcification and lifespan of klotho-deficient mice.
Leibrock CB; Voelkl J; Kohlhofer U; Quintanilla-Martinez L; Kuro-O M; Lang F
Am J Physiol Renal Physiol; 2016 Jan; 310(1):F102-8. PubMed ID: 26538435
[TBL] [Abstract][Full Text] [Related]
19. Plasminogen activator inhibitor 1--insulin-like growth factor binding protein 3 cascade regulates stress-induced senescence.
Elzi DJ; Lai Y; Song M; Hakala K; Weintraub ST; Shiio Y
Proc Natl Acad Sci U S A; 2012 Jul; 109(30):12052-7. PubMed ID: 22778398
[TBL] [Abstract][Full Text] [Related]
20. Regulation of multiple ageing-like phenotypes by inducible klotho gene expression in klotho mutant mice.
Masuda H; Chikuda H; Suga T; Kawaguchi H; Kuro-o M
Mech Ageing Dev; 2005 Dec; 126(12):1274-83. PubMed ID: 16144705
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]