These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
252 related articles for article (PubMed ID: 24786774)
1. Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma. Fresquet V; Rieger M; Carolis C; García-Barchino MJ; Martinez-Climent JA Blood; 2014 Jun; 123(26):4111-9. PubMed ID: 24786774 [TBL] [Abstract][Full Text] [Related]
2. Biological rational for sequential targeting of Bruton tyrosine kinase and Bcl-2 to overcome CD40-induced ABT-199 resistance in mantle cell lymphoma. Chiron D; Dousset C; Brosseau C; Touzeau C; Maïga S; Moreau P; Pellat-Deceunynck C; Le Gouill S; Amiot M Oncotarget; 2015 Apr; 6(11):8750-9. PubMed ID: 25797245 [TBL] [Abstract][Full Text] [Related]
3. The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma. Esteve-Arenys A; Valero JG; Chamorro-Jorganes A; Gonzalez D; Rodriguez V; Dlouhy I; Salaverria I; Campo E; Colomer D; Martinez A; Rymkiewicz G; Pérez-Galán P; Lopez-Guillermo A; Roué G Oncogene; 2018 Apr; 37(14):1830-1844. PubMed ID: 29353886 [TBL] [Abstract][Full Text] [Related]
4. ABT-199, a new Bcl-2-specific BH3 mimetic, has in vivo efficacy against aggressive Myc-driven mouse lymphomas without provoking thrombocytopenia. Vandenberg CJ; Cory S Blood; 2013 Mar; 121(12):2285-8. PubMed ID: 23341542 [TBL] [Abstract][Full Text] [Related]
5. The BH3 mimetic ABT-263 synergizes with the MEK1/2 inhibitor selumetinib/AZD6244 to promote BIM-dependent tumour cell death and inhibit acquired resistance. Sale MJ; Cook SJ Biochem J; 2013 Mar; 450(2):285-94. PubMed ID: 23234544 [TBL] [Abstract][Full Text] [Related]
7. BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy. Pedro JM; Wei Y; Sica V; Maiuri MC; Zou Z; Kroemer G; Levine B Autophagy; 2015; 11(3):452-9. PubMed ID: 25715028 [TBL] [Abstract][Full Text] [Related]
8. Bcl2L12 with a BH3-like domain in regulating apoptosis and TMZ-induced autophagy: a prospective combination of ABT-737 and TMZ for treating glioma. Yang MC; Loh JK; Li YY; Huang WS; Chou CH; Cheng JT; Wang YT; Lieu AS; Howng SL; Hong YR; Chou AK Int J Oncol; 2015 Mar; 46(3):1304-16. PubMed ID: 25586056 [TBL] [Abstract][Full Text] [Related]
9. BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mimetic activity and has only minimal effects on autophagic flux. Reljic B; Conos S; Lee EF; Garnier JM; Dong L; Lessene G; Fairlie WD; Vaux DL; Lindqvist LM Autophagy; 2016 Jul; 12(7):1083-93. PubMed ID: 27172402 [TBL] [Abstract][Full Text] [Related]
10. Potential mechanisms of resistance to venetoclax and strategies to circumvent it. Tahir SK; Smith ML; Hessler P; Rapp LR; Idler KB; Park CH; Leverson JD; Lam LT BMC Cancer; 2017 Jun; 17(1):399. PubMed ID: 28578655 [TBL] [Abstract][Full Text] [Related]
11. DLBCL Cells with Acquired Resistance to Venetoclax Are Not Sensitized to BIRD-2 But Can Be Resensitized to Venetoclax through Bcl-XL Inhibition. Kerkhofs M; Vervloessem T; Stopa KB; Smith VM; Vogler M; Bultynck G Biomolecules; 2020 Jul; 10(7):. PubMed ID: 32708132 [TBL] [Abstract][Full Text] [Related]
12. ABT-737 induces apoptosis in mantle cell lymphoma cells with a Bcl-2high/Mcl-1low profile and synergizes with other antineoplastic agents. Touzeau C; Dousset C; Bodet L; Gomez-Bougie P; Bonnaud S; Moreau A; Moreau P; Pellat-Deceunynck C; Amiot M; Le Gouill S Clin Cancer Res; 2011 Sep; 17(18):5973-81. PubMed ID: 21821698 [TBL] [Abstract][Full Text] [Related]
13. Functional Implications of the spectrum of BCL2 mutations in Lymphoma. Singh K; Briggs JM Mutat Res Rev Mutat Res; 2016; 769():1-18. PubMed ID: 27543313 [TBL] [Abstract][Full Text] [Related]
14. Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia. Iacovelli S; Ricciardi MR; Allegretti M; Mirabilii S; Licchetta R; Bergamo P; Rinaldo C; Zeuner A; Foà R; Milella M; McCubrey JA; Martelli AM; Tafuri A Oncotarget; 2015 Oct; 6(31):32089-103. PubMed ID: 26392332 [TBL] [Abstract][Full Text] [Related]
15. Side-by-side comparison of BH3-mimetics identifies MCL-1 as a key therapeutic target in AML. Ewald L; Dittmann J; Vogler M; Fulda S Cell Death Dis; 2019 Dec; 10(12):917. PubMed ID: 31801941 [TBL] [Abstract][Full Text] [Related]
16. The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism. Anderson MA; Deng J; Seymour JF; Tam C; Kim SY; Fein J; Yu L; Brown JR; Westerman D; Si EG; Majewski IJ; Segal D; Heitner Enschede SL; Huang DC; Davids MS; Letai A; Roberts AW Blood; 2016 Jun; 127(25):3215-24. PubMed ID: 27069256 [TBL] [Abstract][Full Text] [Related]
17. Synergistic induction of apoptosis in high-risk DLBCL by BCL2 inhibition with ABT-199 combined with pharmacologic loss of MCL1. Li L; Pongtornpipat P; Tiutan T; Kendrick SL; Park S; Persky DO; Rimsza LM; Puvvada SD; Schatz JH Leukemia; 2015 Aug; 29(8):1702-12. PubMed ID: 25882699 [TBL] [Abstract][Full Text] [Related]
18. Impact of elevated anti-apoptotic MCL-1 and BCL-2 on the development and treatment of MLL-AF9 AML in mice. Anstee NS; Bilardi RA; Ng AP; Xu Z; Robati M; Vandenberg CJ; Cory S Cell Death Differ; 2019 Jul; 26(7):1316-1331. PubMed ID: 30470795 [TBL] [Abstract][Full Text] [Related]