These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 24791003)

  • 1. Synthesis and gene silencing properties of siRNAs containing terminal amide linkages.
    Gaglione M; Mercurio ME; Potenza N; Mosca N; Russo A; Novellino E; Cosconati S; Messere A
    Biomed Res Int; 2014; 2014():901617. PubMed ID: 24791003
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs.
    Kotikam V; Rozners E
    Acc Chem Res; 2020 Sep; 53(9):1782-1790. PubMed ID: 32658452
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs.
    Mutisya D; Selvam C; Lunstad BD; Pallan PS; Haas A; Leake D; Egli M; Rozners E
    Nucleic Acids Res; 2014 Jun; 42(10):6542-51. PubMed ID: 24813446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gene-silencing properties of siRNAs that contain internal amide-bond linkages.
    Gong W; Desaulniers JP
    Bioorg Med Chem Lett; 2012 Nov; 22(22):6934-7. PubMed ID: 23062704
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and Biological Activity of Short Interfering RNAs Having Several Consecutive Amide Internucleoside Linkages.
    Kotikam V; Viel JA; Rozners E
    Chemistry; 2020 Jan; 26(3):685-690. PubMed ID: 31693228
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of siRNAs that contain internal variable-length spacer linkages.
    Efthymiou TC; Peel B; Huynh V; Desaulniers JP
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5590-4. PubMed ID: 22850216
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of modified double stranded RNAs containing duplex regions between amide-linked RNA and RNA at both ends and enhanced nuclease resistance.
    Iwase R; Kurokawa R; Ueno J
    Nucleic Acids Symp Ser (Oxf); 2009; (53):119-20. PubMed ID: 19749289
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs.
    Mutisya D; Hardcastle T; Cheruiyot SK; Pallan PS; Kennedy SD; Egli M; Kelley ML; Smith AVB; Rozners E
    Nucleic Acids Res; 2017 Aug; 45(14):8142-8155. PubMed ID: 28854734
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and properties of modified siRNA having amide-linked oligoribonucleosides at their 3' overhang regions.
    Iwase R; Miyao H; Toyama T; Nishimori K
    Nucleic Acids Symp Ser (Oxf); 2006; (50):175-6. PubMed ID: 17150874
    [TBL] [Abstract][Full Text] [Related]  

  • 10. siRNA function in RNAi: a chemical modification analysis.
    Chiu YL; Rana TM
    RNA; 2003 Sep; 9(9):1034-48. PubMed ID: 12923253
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for piRNA 2'-O-methylated 3'-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains.
    Tian Y; Simanshu DK; Ma JB; Patel DJ
    Proc Natl Acad Sci U S A; 2011 Jan; 108(3):903-10. PubMed ID: 21193640
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modified siRNAs for the study of the PAZ domain.
    Somoza A; Terrazas M; Eritja R
    Chem Commun (Camb); 2010 Jun; 46(24):4270-2. PubMed ID: 20485810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Computational analysis of siRNA recognition by the Ago2 PAZ domain and identification of the determinants of RNA-induced gene silencing.
    Kandeel M; Kitade Y
    PLoS One; 2013; 8(2):e57140. PubMed ID: 23441235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphate-binding pocket in Dicer-2 PAZ domain for high-fidelity siRNA production.
    Kandasamy SK; Fukunaga R
    Proc Natl Acad Sci U S A; 2016 Dec; 113(49):14031-14036. PubMed ID: 27872309
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and characterization of small interfering RNAs with haloalkyl groups at their 3'-dangling ends.
    Chandela A; Watanabe T; Yamagishi K; Ueno Y
    Bioorg Med Chem; 2019 Apr; 27(7):1341-1349. PubMed ID: 30803746
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of asymmetric terminal structures of short RNA duplexes on the RNA interference activity and strand selection.
    Sano M; Sierant M; Miyagishi M; Nakanishi M; Takagi Y; Sutou S
    Nucleic Acids Res; 2008 Oct; 36(18):5812-21. PubMed ID: 18782830
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Introduction of 2-O-benzyl abasic nucleosides to the 3'-overhang regions of siRNAs greatly improves nuclease resistance.
    Nagaya Y; Kitamura Y; Shibata A; Ikeda M; Akao Y; Kitade Y
    Bioorg Med Chem Lett; 2017 Dec; 27(24):5454-5456. PubMed ID: 29126849
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural Studies and Gene Silencing Activity of siRNAs Containing Cationic Phosphoramidate Linkages.
    Vlaho D; Fakhoury JF; Damha MJ
    Nucleic Acid Ther; 2018 Feb; 28(1):34-43. PubMed ID: 29195060
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, biophysical studies and RNA interference activity of RNA having three consecutive amide linkages.
    Tanui P; Kennedy SD; Lunstad BD; Haas A; Leake D; Rozners E
    Org Biomol Chem; 2014 Feb; 12(8):1207-10. PubMed ID: 24435630
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solid-phase synthesis of modified RNAs containing amide-linked oligoribonucleosides at their 3'-end and their application to siRNA.
    Iwase R; Toyama T; Nishimori K
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(10-12):1451-4. PubMed ID: 18066804
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.