249 related articles for article (PubMed ID: 24795273)
1. Physiological and excessive mechanical compression of articular cartilage activates Smad2/3P signaling.
Madej W; van Caam A; Blaney Davidson EN; van der Kraan PM; Buma P
Osteoarthritis Cartilage; 2014 Jul; 22(7):1018-25. PubMed ID: 24795273
[TBL] [Abstract][Full Text] [Related]
2. Ageing is associated with reduction of mechanically-induced activation of Smad2/3P signaling in articular cartilage.
Madej W; van Caam A; Davidson EN; Hannink G; Buma P; van der Kraan PM
Osteoarthritis Cartilage; 2016 Jan; 24(1):146-57. PubMed ID: 26247611
[TBL] [Abstract][Full Text] [Related]
3. Inflammatory conditions partly impair the mechanically mediated activation of Smad2/3 signaling in articular cartilage.
Madej W; Buma P; van der Kraan P
Arthritis Res Ther; 2016 Jun; 18():146. PubMed ID: 27334538
[TBL] [Abstract][Full Text] [Related]
4. Age-related alterations in TGF beta signaling as a causal factor of cartilage degeneration in osteoarthritis.
van der Kraan PM
Biomed Mater Eng; 2014; 24(1 Suppl):75-80. PubMed ID: 24928920
[TBL] [Abstract][Full Text] [Related]
5. TGF-β is a potent inducer of Nerve Growth Factor in articular cartilage via the ALK5-Smad2/3 pathway. Potential role in OA related pain?
Blaney Davidson EN; van Caam AP; Vitters EL; Bennink MB; Thijssen E; van den Berg WB; Koenders MI; van Lent PL; van de Loo FA; van der Kraan PM
Osteoarthritis Cartilage; 2015 Mar; 23(3):478-86. PubMed ID: 25529198
[TBL] [Abstract][Full Text] [Related]
6. Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.
Blaney Davidson EN; Remst DF; Vitters EL; van Beuningen HM; Blom AB; Goumans MJ; van den Berg WB; van der Kraan PM
J Immunol; 2009 Jun; 182(12):7937-45. PubMed ID: 19494318
[TBL] [Abstract][Full Text] [Related]
7. The high affinity ALK1-ligand BMP9 induces a hypertrophy-like state in chondrocytes that is antagonized by TGFβ1.
van Caam A; Blaney Davidson E; Garcia de Vinuesa A; van Geffen E; van den Berg W; Goumans MJ; ten Dijke P; van der Kraan P
Osteoarthritis Cartilage; 2015 Jun; 23(6):985-95. PubMed ID: 25681563
[TBL] [Abstract][Full Text] [Related]
8. ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.
Finnson KW; Parker WL; ten Dijke P; Thorikay M; Philip A
J Bone Miner Res; 2008 Jun; 23(6):896-906. PubMed ID: 18333754
[TBL] [Abstract][Full Text] [Related]
9. Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.
Li TF; Darowish M; Zuscik MJ; Chen D; Schwarz EM; Rosier RN; Drissi H; O'Keefe RJ
J Bone Miner Res; 2006 Jan; 21(1):4-16. PubMed ID: 16355269
[TBL] [Abstract][Full Text] [Related]
10. TGF-ß induces Lysyl hydroxylase 2b in human synovial osteoarthritic fibroblasts through ALK5 signaling.
Remst DF; Blaney Davidson EN; Vitters EL; Bank RA; van den Berg WB; van der Kraan PM
Cell Tissue Res; 2014 Jan; 355(1):163-71. PubMed ID: 24192939
[TBL] [Abstract][Full Text] [Related]
11. Cross-talk between TGF-beta/SMAD and integrin signaling pathways in regulating hypertrophy of mesenchymal stem cell chondrogenesis under deferral dynamic compression.
Zhang T; Wen F; Wu Y; Goh GS; Ge Z; Tan LP; Hui JH; Yang Z
Biomaterials; 2015 Jan; 38():72-85. PubMed ID: 25453975
[TBL] [Abstract][Full Text] [Related]
12. Separating friend from foe: Inhibition of TGF-β-induced detrimental SMAD1/5/9 phosphorylation while maintaining protective SMAD2/3 signaling in OA chondrocytes.
Thielen NGM; van Caam APM; V Beuningen HM; Vitters EL; van den Bosch MHJ; Koenders MI; van de Loo FAJ; Blaney Davidson EN; van der Kraan PM
Osteoarthritis Cartilage; 2023 Nov; 31(11):1481-1490. PubMed ID: 37652257
[TBL] [Abstract][Full Text] [Related]
13. Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
Wang Q; Tan QY; Xu W; Qi HB; Chen D; Zhou S; Ni ZH; Kuang L; Guo JY; Huang JL; Wang XX; Wang ZQ; Su N; Chen L; Chen B; Jiang WL; Gao Y; Chen HG; Du XL; Xie YL; Chen L
Osteoarthritis Cartilage; 2017 Nov; 25(11):1868-1879. PubMed ID: 28716756
[TBL] [Abstract][Full Text] [Related]
14. Induction of high temperature requirement A1, a serine protease, by TGF-beta1 in articular chondrocytes of mouse models of OA.
Xu L; Golshirazian I; Asbury BJ; Li Y
Histol Histopathol; 2014 May; 29(5):609-18. PubMed ID: 24135912
[TBL] [Abstract][Full Text] [Related]
15. A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis.
van der Kraan PM; Blaney Davidson EN; van den Berg WB
Arthritis Res Ther; 2010; 12(1):201. PubMed ID: 20156325
[TBL] [Abstract][Full Text] [Related]
16. Endoglin differentially regulates TGF-β-induced Smad2/3 and Smad1/5 signalling and its expression correlates with extracellular matrix production and cellular differentiation state in human chondrocytes.
Finnson KW; Parker WL; Chi Y; Hoemann CD; Goldring MB; Antoniou J; Philip A
Osteoarthritis Cartilage; 2010 Nov; 18(11):1518-27. PubMed ID: 20833252
[TBL] [Abstract][Full Text] [Related]
17. Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes.
Bougault C; Aubert-Foucher E; Paumier A; Perrier-Groult E; Huot L; Hot D; Duterque-Coquillaud M; Mallein-Gerin F
PLoS One; 2012; 7(5):e36964. PubMed ID: 22615857
[TBL] [Abstract][Full Text] [Related]
18. Age-dependent alteration of TGF-β signalling in osteoarthritis.
van der Kraan PM; Goumans MJ; Blaney Davidson E; ten Dijke P
Cell Tissue Res; 2012 Jan; 347(1):257-65. PubMed ID: 21638205
[TBL] [Abstract][Full Text] [Related]
19. TGF-β1, but not bone morphogenetic proteins, activates Smad1/5 pathway in primary human macrophages and induces expression of proatherogenic genes.
Nurgazieva D; Mickley A; Moganti K; Ming W; Ovsyi I; Popova A; Sachindra ; Awad K; Wang N; Bieback K; Goerdt S; Kzhyshkowska J; Gratchev A
J Immunol; 2015 Jan; 194(2):709-18. PubMed ID: 25505291
[TBL] [Abstract][Full Text] [Related]
20. Differential TGF-{beta} signaling in retinal vascular cells: a role in diabetic retinopathy?
Van Geest RJ; Klaassen I; Vogels IM; Van Noorden CJ; Schlingemann RO
Invest Ophthalmol Vis Sci; 2010 Apr; 51(4):1857-65. PubMed ID: 19959647
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
