156 related articles for article (PubMed ID: 24801499)
1. Methyl substitution of a rexinoid agonist improves potency and reveals site of lipid toxicity.
Atigadda VR; Xia G; Desphande A; Boerma LJ; Lobo-Ruppert S; Grubbs CJ; Smith CD; Brouillette WJ; Muccio DD
J Med Chem; 2014 Jun; 57(12):5370-80. PubMed ID: 24801499
[TBL] [Abstract][Full Text] [Related]
2. Conformationally defined retinoic acid analogues. 5. Large-scale synthesis and mammary cancer chemopreventive activity for (2E,4E,6Z,8E)-8-(3',4'-dihydro-1'(2'H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid (9cUAB30).
Atigadda VR; Vines KK; Grubbs CJ; Hill DL; Beenken SL; Bland KI; Brouillette WJ; Muccio DD
J Med Chem; 2003 Aug; 46(17):3766-9. PubMed ID: 12904083
[TBL] [Abstract][Full Text] [Related]
3. Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers.
Atigadda VR; Xia G; Deshpande A; Wu L; Kedishvili N; Smith CD; Krontiras H; Bland KI; Grubbs CJ; Brouillette WJ; Muccio DD
J Med Chem; 2015 Oct; 58(19):7763-74. PubMed ID: 26331194
[TBL] [Abstract][Full Text] [Related]
4. Defining the communication between agonist and coactivator binding in the retinoid X receptor α ligand binding domain.
Boerma LJ; Xia G; Qui C; Cox BD; Chalmers MJ; Smith CD; Lobo-Ruppert S; Griffin PR; Muccio DD; Renfrow MB
J Biol Chem; 2014 Jan; 289(2):814-26. PubMed ID: 24187139
[TBL] [Abstract][Full Text] [Related]
5. Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention.
Desphande A; Xia G; Boerma LJ; Vines KK; Atigadda VR; Lobo-Ruppert S; Grubbs CJ; Moeinpour FL; Smith CD; Christov K; Brouillette WJ; Muccio DD
Bioorg Med Chem; 2014 Jan; 22(1):178-85. PubMed ID: 24359708
[TBL] [Abstract][Full Text] [Related]
6. Chemopreventive effects of RXR-selective rexinoid bexarotene on intestinal neoplasia of Apc(Min/+) mice.
Janakiram NB; Mohammed A; Qian L; Choi CI; Steele VE; Rao CV
Neoplasia; 2012 Feb; 14(2):159-68. PubMed ID: 22431924
[TBL] [Abstract][Full Text] [Related]
7. The retinoid X receptor agonist, 9-cis UAB30, inhibits cutaneous T-cell lymphoma proliferation through the SKP2-p27kip1 axis.
Chou CF; Hsieh YH; Grubbs CJ; Atigadda VR; Mobley JA; Dummer R; Muccio DD; Eto I; Elmets CA; Garvey WT; Chang PL
J Dermatol Sci; 2018 Jun; 90(3):343-356. PubMed ID: 29599065
[TBL] [Abstract][Full Text] [Related]
8. Effects on gene expression in rat liver after administration of RXR agonists: UAB30, 4-methyl-UAB30, and Targretin (Bexarotene).
Vedell PT; Lu Y; Grubbs CJ; Yin Y; Jiang H; Bland KI; Muccio DD; Cvetkovic D; You M; Lubet R
Mol Pharmacol; 2013 Mar; 83(3):698-708. PubMed ID: 23292798
[TBL] [Abstract][Full Text] [Related]
9. The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice.
Li Y; Zhang Y; Hill J; Kim HT; Shen Q; Bissonnette RP; Lamph WW; Brown PH
Br J Cancer; 2008 Apr; 98(8):1380-8. PubMed ID: 18362934
[TBL] [Abstract][Full Text] [Related]
10. In vitro metabolic characterization, phenotyping, and kinetic studies of 9cUAB30, a retinoid X receptor-specific retinoid.
Gorman GS; Coward L; Kerstner-Wood C; Cork L; Kapetanovic IM; Brouillette WJ; Muccio DD
Drug Metab Dispos; 2007 Jul; 35(7):1157-64. PubMed ID: 17446266
[TBL] [Abstract][Full Text] [Related]
11. Murine oncogenicity and pharmacokinetics studies of 9-cis-UAB30, an RXR agonist, for breast cancer chemoprevention.
Kapetanovic IM; Horn TL; Johnson WD; Cwik MJ; Detrisac CJ; McCormick DL
Int J Toxicol; 2010; 29(2):157-64. PubMed ID: 20335511
[TBL] [Abstract][Full Text] [Related]
12. The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer.
Moerland JA; Zhang D; Reich LA; Carapellucci S; Lockwood B; Leal AS; Krieger-Burke T; Aleiwi B; Ellsworth E; Liby KT
Sci Rep; 2020 Dec; 10(1):22244. PubMed ID: 33335263
[TBL] [Abstract][Full Text] [Related]
13. Methods to Assess Activity and Potency of Rexinoids Using Rapid Luciferase-Based Assays: A Case Study with NEt-TMN.
Jurutka PW; Wagner CE
Methods Mol Biol; 2019; 2019():95-108. PubMed ID: 31359391
[TBL] [Abstract][Full Text] [Related]
14. Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid.
Jiang W; Deng W; Bailey SK; Nail CD; Frost AR; Brouillette WJ; Muccio DD; Grubbs CJ; Ruppert JM; Lobo-Ruppert SM
Cancer Biol Ther; 2009 Feb; 8(3):289-98. PubMed ID: 19197145
[TBL] [Abstract][Full Text] [Related]
15. 9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers.
Grubbs CJ; Hill DL; Bland KI; Beenken SW; Lin TH; Eto I; Atigadda VR; Vines KK; Brouillette WJ; Muccio DD
Cancer Lett; 2003 Nov; 201(1):17-24. PubMed ID: 14580682
[TBL] [Abstract][Full Text] [Related]
16. Src is a novel potential off-target of RXR agonists, 9-cis-UAB30 and Targretin, in human breast cancer cells.
Kim MS; Lim DY; Kim JE; Chen H; Lubet RA; Dong Z; Bode AM
Mol Carcinog; 2015 Dec; 54(12):1596-604. PubMed ID: 25328014
[TBL] [Abstract][Full Text] [Related]
17. Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias.
Muccio DD; Brouillette WJ; Breitman TR; Taimi M; Emanuel PD; Zhang X; Chen G; Sani BP; Venepally P; Reddy L; Alam M; Simpson-Herren L; Hill DL
J Med Chem; 1998 May; 41(10):1679-87. PubMed ID: 9572893
[TBL] [Abstract][Full Text] [Related]
18. Rexinoid-induced expression of IGFBP-6 requires RARbeta-dependent permissive cooperation of retinoid receptors and AP-1.
Uray IP; Shen Q; Seo HS; Kim H; Lamph WW; Bissonnette RP; Brown PH
J Biol Chem; 2009 Jan; 284(1):345-353. PubMed ID: 18957410
[TBL] [Abstract][Full Text] [Related]
19. Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers.
Grubbs CJ; Lubet RA; Atigadda VR; Christov K; Deshpande AM; Tirmal V; Xia G; Bland KI; Eto I; Brouillette WJ; Muccio DD
Carcinogenesis; 2006 Jun; 27(6):1232-9. PubMed ID: 16344269
[TBL] [Abstract][Full Text] [Related]
20. Rexinoids isolated from Sophora tonkinensis with a gene expression profile distinct from the synthetic rexinoid bexarotene.
Inoue M; Tanabe H; Nakashima K; Ishida Y; Kotani H
J Nat Prod; 2014 Jul; 77(7):1670-7. PubMed ID: 24959987
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]