BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 24810052)

  • 1. Celastrol targets proteostasis and acts synergistically with a heat-shock protein 90 inhibitor to kill human glioblastoma cells.
    Boridy S; Le PU; Petrecca K; Maysinger D
    Cell Death Dis; 2014 May; 5(5):e1216. PubMed ID: 24810052
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers.
    Raja SM; Clubb RJ; Ortega-Cava C; Williams SH; Bailey TA; Duan L; Zhao X; Reddi AL; Nyong AM; Natarajan A; Band V; Band H
    Cancer Biol Ther; 2011 Jan; 11(2):263-76. PubMed ID: 21088503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells.
    Chen G; Zhang X; Zhao M; Wang Y; Cheng X; Wang D; Xu Y; Du Z; Yu X
    BMC Cancer; 2011 May; 11():170. PubMed ID: 21569548
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90.
    Wang WB; Feng LX; Yue QX; Wu WY; Guan SH; Jiang BH; Yang M; Liu X; Guo DA
    J Cell Physiol; 2012 May; 227(5):2196-206. PubMed ID: 21866552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells.
    Castagnola P; Bellese G; Birocchi F; Gagliani MC; Tacchetti C; Cortese K
    Oncotarget; 2016 Dec; 7(51):85411-85429. PubMed ID: 27863425
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Combined inhibition of Hsp90 and the proteasome affects NSCLC proteostasis and attenuates cell migration.
    Zismanov V; Drucker L; Gottfried M
    Anticancer Drugs; 2014 Oct; 25(9):998-1006. PubMed ID: 25153785
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synergistic anticancer effects of triptolide and celastrol, two main compounds from thunder god vine.
    Jiang QW; Cheng KJ; Mei XL; Qiu JG; Zhang WJ; Xue YQ; Qin WM; Yang Y; Zheng DW; Chen Y; Wei MN; Zhang X; Lv M; Chen MW; Wei X; Shi Z
    Oncotarget; 2015 Oct; 6(32):32790-804. PubMed ID: 26447544
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of inhibition of the ubiquitin-proteasome system and Hsp90 on growth and survival of rhabdomyosarcoma cells in vitro.
    Peron M; Bonvini P; Rosolen A
    BMC Cancer; 2012 Jun; 12():233. PubMed ID: 22691173
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of heat shock protein 27 using OGX-427 induces endoplasmic reticulum stress and potentiates heat shock protein 90 inhibitors to delay castrate-resistant prostate cancer.
    Lamoureux F; Thomas C; Yin MJ; Fazli L; Zoubeidi A; Gleave ME
    Eur Urol; 2014 Jul; 66(1):145-55. PubMed ID: 24411988
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HSP27 knockdown produces synergistic induction of apoptosis by HSP90 and kinase inhibitors in glioblastoma multiforme.
    Belkacemi L; Hebb MO
    Anticancer Res; 2014 Sep; 34(9):4915-27. PubMed ID: 25202074
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90.
    Dungey FA; Caldecott KW; Chalmers AJ
    Mol Cancer Ther; 2009 Aug; 8(8):2243-54. PubMed ID: 19671736
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.
    Schaefer S; Svenstrup TH; Guerra B
    PLoS One; 2017; 12(5):e0177706. PubMed ID: 28542269
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nonsteroidal Anti-inflammatory Drugs Sensitize CD44-Overexpressing Cancer Cells to Hsp90 Inhibitor Through Autophagy Activation.
    Moon HJ; Park SY; Lee SH; Kang CD; Kim SH
    Oncol Res; 2019 Jul; 27(7):835-847. PubMed ID: 30982499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carbamazepine promotes Her-2 protein degradation in breast cancer cells by modulating HDAC6 activity and acetylation of Hsp90.
    Meng Q; Chen X; Sun L; Zhao C; Sui G; Cai L
    Mol Cell Biochem; 2011 Feb; 348(1-2):165-71. PubMed ID: 21082217
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
    Francis LK; Alsayed Y; Leleu X; Jia X; Singha UK; Anderson J; Timm M; Ngo H; Lu G; Huston A; Ehrlich LA; Dimmock E; Lentzsch S; Hideshima T; Roodman GD; Anderson KC; Ghobrial IM
    Clin Cancer Res; 2006 Nov; 12(22):6826-35. PubMed ID: 17121904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hsp90 inhibitor geldanamycin attenuates the cytotoxicity of sunitinib in cardiomyocytes via inhibition of the autophagy pathway.
    Kimura T; Uesugi M; Takase K; Miyamoto N; Sawada K
    Toxicol Appl Pharmacol; 2017 Aug; 329():282-292. PubMed ID: 28624441
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis.
    Powers MV; Clarke PA; Workman P
    Cancer Cell; 2008 Sep; 14(3):250-62. PubMed ID: 18772114
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Autophagy inhibition sensitizes multiple myeloma cells to 17-dimethylaminoethylamino-17-demethoxygeldanamycin-induced apoptosis.
    Palacios C; Martín-Pérez R; López-Pérez AI; Pandiella A; López-Rivas A
    Leuk Res; 2010 Nov; 34(11):1533-8. PubMed ID: 20667592
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of 90-kD heat shock protein potentiates the cytotoxicity of chemotherapeutic agents in human glioma cells.
    Ohba S; Hirose Y; Yoshida K; Yazaki T; Kawase T
    J Neurosurg; 2010 Jan; 112(1):33-42. PubMed ID: 19408974
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.
    Miekus K; Kijowski J; Sekuła M; Majka M
    Oncol Rep; 2012 Nov; 28(5):1903-9. PubMed ID: 22941268
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.