These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 24814347)

  • 1. The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
    Follis AV; Llambi F; Ou L; Baran K; Green DR; Kriwacki RW
    Nat Struct Mol Biol; 2014 Jun; 21(6):535-43. PubMed ID: 24814347
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The DNA binding domain of p53 is sufficient to trigger a potent apoptotic response at the mitochondria.
    Matissek KJ; Mossalam M; Okal A; Lim CS
    Mol Pharm; 2013 Oct; 10(10):3592-602. PubMed ID: 23968395
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis.
    Follis AV; Chipuk JE; Fisher JC; Yun MK; Grace CR; Nourse A; Baran K; Ou L; Min L; White SW; Green DR; Kriwacki RW
    Nat Chem Biol; 2013 Mar; 9(3):163-8. PubMed ID: 23340338
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The N-terminal domain of tumor suppressor p53 is involved in the molecular interaction with the anti-apoptotic protein Bcl-Xl.
    Xu H; Tai J; Ye H; Kang CB; Yoon HS
    Biochem Biophys Res Commun; 2006 Mar; 341(4):938-44. PubMed ID: 16455050
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis.
    Chipuk JE; Kuwana T; Bouchier-Hayes L; Droin NM; Newmeyer DD; Schuler M; Green DR
    Science; 2004 Feb; 303(5660):1010-4. PubMed ID: 14963330
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BCL-XL binds and antagonizes RASSF6 tumor suppressor to suppress p53 expression.
    Xu X; Iwasa H; Hossain S; Sarkar A; Maruyama J; Arimoto-Matsuzaki K; Hata Y
    Genes Cells; 2017 Dec; 22(12):993-1003. PubMed ID: 29193479
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting of p53 peptide analogues to anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy.
    Shin JS; Ha JH; Chi SW
    Biochem Biophys Res Commun; 2014 Jan; 443(3):882-7. PubMed ID: 24342622
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-apoptosis proteins Mcl-1 and Bcl-xL have different p53-binding profiles.
    Yao H; Mi S; Gong W; Lin J; Xu N; Perrett S; Xia B; Wang J; Feng Y
    Biochemistry; 2013 Sep; 52(37):6324-34. PubMed ID: 23977882
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways.
    Ha JH; Shin JS; Yoon MK; Lee MS; He F; Bae KH; Yoon HS; Lee CK; Park SG; Muto Y; Chi SW
    J Biol Chem; 2013 Mar; 288(10):7387-98. PubMed ID: 23316052
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discoveries and controversies in BCL-2 protein-mediated apoptosis.
    Zheng JH; Viacava Follis A; Kriwacki RW; Moldoveanu T
    FEBS J; 2016 Jul; 283(14):2690-700. PubMed ID: 26411300
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.
    Malia TJ; Wagner G
    Biochemistry; 2007 Jan; 46(2):514-25. PubMed ID: 17209561
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Structural Biology of Bcl-x
    Lee EF; Fairlie WD
    Int J Mol Sci; 2019 May; 20(9):. PubMed ID: 31067648
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PUMA couples the nuclear and cytoplasmic proapoptotic function of p53.
    Chipuk JE; Bouchier-Hayes L; Kuwana T; Newmeyer DD; Green DR
    Science; 2005 Sep; 309(5741):1732-5. PubMed ID: 16151013
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-xL.
    Sot B; Freund SM; Fersht AR
    J Biol Chem; 2007 Oct; 282(40):29193-200. PubMed ID: 17699158
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural insight into the molecular mechanism of p53-mediated mitochondrial apoptosis.
    Wei H; Qu L; Dai S; Li Y; Wang H; Feng Y; Chen X; Jiang L; Guo M; Li J; Chen Z; Chen L; Zhang Y; Chen Y
    Nat Commun; 2021 Apr; 12(1):2280. PubMed ID: 33863900
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel mechanism of irinotecan targeting MDM2 and Bcl-xL.
    Lee B; Min JA; Nashed A; Lee SO; Yoo JC; Chi SW; Yi GS
    Biochem Biophys Res Commun; 2019 Jun; 514(2):518-523. PubMed ID: 31056264
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.
    Lee MS; Ha JH; Yoon HS; Lee CK; Chi SW
    Biochem Biophys Res Commun; 2014 Feb; 445(1):120-5. PubMed ID: 24491548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas.
    Lee TL; Yeh J; Friedman J; Yan B; Yang X; Yeh NT; Van Waes C; Chen Z
    Int J Cancer; 2008 May; 122(9):1987-98. PubMed ID: 18172861
    [TBL] [Abstract][Full Text] [Related]  

  • 19. After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization.
    Ding J; Mooers BHM; Zhang Z; Kale J; Falcone D; McNichol J; Huang B; Zhang XC; Xing C; Andrews DW; Lin J
    J Biol Chem; 2014 Apr; 289(17):11873-11896. PubMed ID: 24616095
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1.
    Feng W; Huang S; Wu H; Zhang M
    J Mol Biol; 2007 Sep; 372(1):223-35. PubMed ID: 17659302
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.