These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
233 related articles for article (PubMed ID: 24815013)
1. Systematic domain swaps of iterative, nonreducing polyketide synthases provide a mechanistic understanding and rationale for catalytic reprogramming. Newman AG; Vagstad AL; Storm PA; Townsend CA J Am Chem Soc; 2014 May; 136(20):7348-62. PubMed ID: 24815013 [TBL] [Abstract][Full Text] [Related]
2. Starter unit flexibility for engineered product synthesis by the nonreducing polyketide synthase PksA. Huitt-Roehl CR; Hill EA; Adams MM; Vagstad AL; Li JW; Townsend CA ACS Chem Biol; 2015 Jun; 10(6):1443-9. PubMed ID: 25714897 [TBL] [Abstract][Full Text] [Related]
3. The Structural Enzymology of Iterative Aromatic Polyketide Synthases: A Critical Comparison with Fatty Acid Synthases. Tsai SC Annu Rev Biochem; 2018 Jun; 87():503-531. PubMed ID: 29925265 [TBL] [Abstract][Full Text] [Related]
4. Structure and function of an iterative polyketide synthase thioesterase domain catalyzing Claisen cyclization in aflatoxin biosynthesis. Korman TP; Crawford JM; Labonte JW; Newman AG; Wong J; Townsend CA; Tsai SC Proc Natl Acad Sci U S A; 2010 Apr; 107(14):6246-51. PubMed ID: 20332208 [TBL] [Abstract][Full Text] [Related]
5. Polyketide mimetics yield structural and mechanistic insights into product template domain function in nonreducing polyketide synthases. Barajas JF; Shakya G; Moreno G; Rivera H; Jackson DR; Topper CL; Vagstad AL; La Clair JJ; Townsend CA; Burkart MD; Tsai SC Proc Natl Acad Sci U S A; 2017 May; 114(21):E4142-E4148. PubMed ID: 28484029 [TBL] [Abstract][Full Text] [Related]
6. Rational domain swaps reveal insights about chain length control by ketosynthase domains in fungal nonreducing polyketide synthases. Liu T; Sanchez JF; Chiang YM; Oakley BR; Wang CC Org Lett; 2014 Mar; 16(6):1676-9. PubMed ID: 24593241 [TBL] [Abstract][Full Text] [Related]
7. Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation. Kapur S; Lowry B; Yuzawa S; Kenthirapalan S; Chen AY; Cane DE; Khosla C Proc Natl Acad Sci U S A; 2012 Mar; 109(11):4110-5. PubMed ID: 22371562 [TBL] [Abstract][Full Text] [Related]
8. Biosynthesis of aromatic polyketides in microorganisms using type II polyketide synthases. Wang J; Zhang R; Chen X; Sun X; Yan Y; Shen X; Yuan Q Microb Cell Fact; 2020 May; 19(1):110. PubMed ID: 32448179 [TBL] [Abstract][Full Text] [Related]
9. Iterative polyketide biosynthesis by modular polyketide synthases in bacteria. Chen H; Du L Appl Microbiol Biotechnol; 2016 Jan; 100(2):541-57. PubMed ID: 26549236 [TBL] [Abstract][Full Text] [Related]
10. Thioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis. Xu Y; Zhou T; Zhang S; Xuan LJ; Zhan J; Molnár I J Am Chem Soc; 2013 Jul; 135(29):10783-91. PubMed ID: 23822773 [TBL] [Abstract][Full Text] [Related]
11. Modular Halogenation, α-Hydroxylation, and Acylation by a Remarkably Versatile Polyketide Synthase. Hemmerling F; Meoded RA; Fraley AE; Minas HA; Dieterich CL; Rust M; Ueoka R; Jensen K; Helfrich EJN; Bergande C; Biedermann M; Magnus N; Piechulla B; Piel J Angew Chem Int Ed Engl; 2022 Mar; 61(11):e202116614. PubMed ID: 35020279 [TBL] [Abstract][Full Text] [Related]
12. Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase. Crawford JM; Dancy BC; Hill EA; Udwary DW; Townsend CA Proc Natl Acad Sci U S A; 2006 Nov; 103(45):16728-33. PubMed ID: 17071746 [TBL] [Abstract][Full Text] [Related]
13. Interrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity. Vagstad AL; Bumpus SB; Belecki K; Kelleher NL; Townsend CA J Am Chem Soc; 2012 Apr; 134(15):6865-77. PubMed ID: 22452347 [TBL] [Abstract][Full Text] [Related]
14. An Oxetane-Based Polyketide Surrogate To Probe Substrate Binding in a Polyketide Synthase. Ellis BD; Milligan JC; White AR; Duong V; Altman PX; Mohammed LY; Crump MP; Crosby J; Luo R; Vanderwal CD; Tsai SC J Am Chem Soc; 2018 Apr; 140(15):4961-4964. PubMed ID: 29620883 [TBL] [Abstract][Full Text] [Related]