119 related articles for article (PubMed ID: 24824658)
1. Structure-activity relationship studies of N-methylated and N-hydroxylated spider polyamine toxins as inhibitors of ionotropic glutamate receptors.
Nørager NG; Poulsen MH; Jensen AG; Jeppesen NS; Kristensen AS; Strømgaard K
J Med Chem; 2014 Jun; 57(11):4940-9. PubMed ID: 24824658
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationship study of spider polyamine toxins as inhibitors of ionotropic glutamate receptors.
Xiong XF; Poulsen MH; Hussein RA; Nørager NG; Strømgaard K
ChemMedChem; 2014 Dec; 9(12):2661-70. PubMed ID: 25267300
[TBL] [Abstract][Full Text] [Related]
3. Polyamine toxins: development of selective ligands for ionotropic receptors.
Strømgaard K; Jensen LS; Vogensen SB
Toxicon; 2005 Mar; 45(3):249-54. PubMed ID: 15683862
[TBL] [Abstract][Full Text] [Related]
4. Solid-phase synthesis and biological evaluation of Joro spider toxin-4 from Nephila clavata.
Barslund AF; Poulsen MH; Bach TB; Lucas S; Kristensen AS; Strømgaard K
J Nat Prod; 2011 Mar; 74(3):483-6. PubMed ID: 21188966
[TBL] [Abstract][Full Text] [Related]
5. Selective antagonism of native and cloned kainate and NMDA receptors by polyamine-containing toxins.
Brackley PT; Bell DR; Choi SK; Nakanishi K; Usherwood PN
J Pharmacol Exp Ther; 1993 Sep; 266(3):1573-80. PubMed ID: 7690404
[TBL] [Abstract][Full Text] [Related]
6. Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: discovery of nanomolar, nonselective, and use-dependent antagonists.
Frølund S; Bella A; Kristensen AS; Ziegler HL; Witt M; Olsen CA; Strømgaard K; Franzyk H; Jaroszewski JW
J Med Chem; 2010 Oct; 53(20):7441-51. PubMed ID: 20873775
[TBL] [Abstract][Full Text] [Related]
7. Effects of Agelenopsis aperta toxins on the N-methyl-D-aspartate receptor: polyamine-like and high-affinity antagonist actions.
Williams K
J Pharmacol Exp Ther; 1993 Jul; 266(1):231-6. PubMed ID: 7687289
[TBL] [Abstract][Full Text] [Related]
8. General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors.
Lucas S; Poulsen MH; Nørager NG; Barslund AF; Bach TB; Kristensen AS; Strømgaard K
J Med Chem; 2012 Nov; 55(22):10297-301. PubMed ID: 23092360
[TBL] [Abstract][Full Text] [Related]
9. Structure-activity relationship studies of argiotoxins: selective and potent inhibitors of ionotropic glutamate receptors.
Poulsen MH; Lucas S; Bach TB; Barslund AF; Wenzler C; Jensen CB; Kristensen AS; Strømgaard K
J Med Chem; 2013 Feb; 56(3):1171-81. PubMed ID: 23320429
[TBL] [Abstract][Full Text] [Related]
10. Uncompetitive antagonism of AMPA receptors: Mechanistic insights from studies of polyamine toxin derivatives.
Andersen TF; Tikhonov DB; Bølcho U; Bolshakov K; Nelson JK; Pluteanu F; Mellor IR; Egebjerg J; Strømgaard K
J Med Chem; 2006 Sep; 49(18):5414-23. PubMed ID: 16942015
[TBL] [Abstract][Full Text] [Related]
11. Solid-phase synthesis of polyamine toxin analogues: potent and selective antagonists of Ca2+-permeable AMPA receptors.
Kromann H; Krikstolaityte S; Andersen AJ; Andersen K; Krogsgaard-Larsen P; Jaroszewski JW; Egebjerg J; Strømgaard K
J Med Chem; 2002 Dec; 45(26):5745-54. PubMed ID: 12477358
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological activity of argiotoxin 636 and analogues: selective antagonists for ionotropic glutamate receptors.
Nelson JK; Frølund SU; Tikhonov DB; Kristensen AS; Strømgaard K
Angew Chem Int Ed Engl; 2009; 48(17):3087-91. PubMed ID: 19152392
[TBL] [Abstract][Full Text] [Related]
13. The effects of conformational constraints in the polyamine moiety of philanthotoxins on AMPAR inhibition.
Franzyk H; Grzeskowiak JW; Tikhonov DB; Jaroszewski JW; Mellor IR
ChemMedChem; 2014 Aug; 9(8):1725-31. PubMed ID: 25044789
[TBL] [Abstract][Full Text] [Related]
14. Development of potent fluorescent polyamine toxins and application in labeling of ionotropic glutamate receptors in hippocampal neurons.
Nørager NG; Jensen CB; Rathje M; Andersen J; Madsen KL; Kristensen AS; Strømgaard K
ACS Chem Biol; 2013 Sep; 8(9):2033-41. PubMed ID: 23838571
[TBL] [Abstract][Full Text] [Related]
15. AMPA receptor ligands: synthetic and pharmacological studies of polyamines and polyamine toxins.
Strømgaard K; Mellor I
Med Res Rev; 2004 Sep; 24(5):589-620. PubMed ID: 15224382
[TBL] [Abstract][Full Text] [Related]
16. Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.
Masuko T; Namiki R; Nemoto Y; Miyake M; Kizawa Y; Suzuki T; Kashiwagi K; Igarashi K; Kusama T
J Pharmacol Exp Ther; 2009 Nov; 331(2):522-30. PubMed ID: 19644042
[TBL] [Abstract][Full Text] [Related]
17. 4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues.
Lolli ML; Giordano C; Pickering DS; Rolando B; Hansen KB; Foti A; Contreras-Sanz A; Amir A; Fruttero R; Gasco A; Nielsen B; Johansen TN
J Med Chem; 2010 May; 53(10):4110-8. PubMed ID: 20408529
[TBL] [Abstract][Full Text] [Related]
18. Regioselective solid-phase synthesis of N-mono-hydroxylated and N-mono-methylated acylpolyamine spider toxins using an 2-(ortho-nitrophenyl)ethanal-modified resin.
Pauli D; Bienz S
Org Biomol Chem; 2015 Apr; 13(15):4473-85. PubMed ID: 25773373
[TBL] [Abstract][Full Text] [Related]
19. Block of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by polyamines and polyamine toxins.
Washburn MS; Dingledine R
J Pharmacol Exp Ther; 1996 Aug; 278(2):669-78. PubMed ID: 8768718
[TBL] [Abstract][Full Text] [Related]
20. Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors.
Mellor IR; Brier TJ; Pluteanu F; Strømgaard K; Saghyan A; Eldursi N; Brierley MJ; Andersen K; Jaroszewski JW; Krogsgaard-Larsen P; Usherwood PN
Neuropharmacology; 2003 Jan; 44(1):70-80. PubMed ID: 12559123
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
