These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 24830845)

  • 1. Design of p53-derived peptides with cytotoxicity on breast cancer.
    Fang Y; Jin R; Gao Y; Gao J; Wang J
    Amino Acids; 2014 Aug; 46(8):2015-24. PubMed ID: 24830845
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recognition Dynamics of p53 and MDM2: Implications for Peptide Design.
    ElSawy KM; Lane DP; Verma CS; Caves LS
    J Phys Chem B; 2016 Jan; 120(2):320-8. PubMed ID: 26701330
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site.
    Do TN; Rosal RV; Drew L; Raffo AJ; Michl J; Pincus MR; Friedman FK; Petrylak DP; Cassai N; Szmulewicz J; Sidhu G; Fine RL; Brandt-Rauf PW
    Oncogene; 2003 Mar; 22(10):1431-44. PubMed ID: 12629507
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.
    Lee MS; Ha JH; Yoon HS; Lee CK; Chi SW
    Biochem Biophys Res Commun; 2014 Feb; 445(1):120-5. PubMed ID: 24491548
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and development of high affinity dual anticancer peptide-inhibitors against p53-MDM2/X interaction.
    Rasafar N; Barzegar A; Mehdizadeh Aghdam E
    Life Sci; 2020 Mar; 245():117358. PubMed ID: 32001262
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-based designing efficient peptides based on p53 binding site residues to disrupt p53-MDM2/X interaction.
    Rasafar N; Barzegar A; Mehdizadeh Aghdam E
    Sci Rep; 2020 Jul; 10(1):11449. PubMed ID: 32651397
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction. Part 2.
    Wang W; Lv D; Qiu N; Zhang L; Hu C; Hu Y
    Bioorg Med Chem; 2013 Jun; 21(11):2886-94. PubMed ID: 23611770
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors.
    Noguchi T; Oishi S; Honda K; Kondoh Y; Saito T; Kubo T; Kaneda M; Ohno H; Osada H; Fujii N
    Bioorg Med Chem Lett; 2013 Jul; 23(13):3802-5. PubMed ID: 23726030
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Group-based QSAR and molecular dynamics mechanistic analysis revealing the mode of action of novel piperidinone derived protein-protein inhibitors of p53-MDM2.
    Goyal S; Grover S; Dhanjal JK; Tyagi C; Goyal M; Grover A
    J Mol Graph Model; 2014 Jun; 51():64-72. PubMed ID: 24858256
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proposing novel MDM2 inhibitors: Combined physics-driven high-throughput virtual screening and in vitro studies.
    Aydin G; Paksoy MN; Orhan MD; Avsar T; Yurtsever M; Durdagi S
    Chem Biol Drug Des; 2020 Jul; 96(1):684-700. PubMed ID: 32691963
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of the stapled p53 peptide bound to Mdm2.
    Baek S; Kutchukian PS; Verdine GL; Huber R; Holak TA; Lee KW; Popowicz GM
    J Am Chem Soc; 2012 Jan; 134(1):103-6. PubMed ID: 22148351
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells.
    Philippe GJ; Mittermeier A; Lawrence N; Huang YH; Condon ND; Loewer A; Craik DJ; Henriques ST
    ACS Chem Biol; 2021 Feb; 16(2):414-428. PubMed ID: 33533253
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Probing the origin of structural stability of single and double stapled p53 peptide analogs bound to MDM2.
    Guo Z; Streu K; Krilov G; Mohanty U
    Chem Biol Drug Des; 2014 Jun; 83(6):631-42. PubMed ID: 24418072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of a new small-molecule inhibitor of p53-MDM2 interaction using a yeast-based approach.
    Leão M; Pereira C; Bisio A; Ciribilli Y; Paiva AM; Machado N; Palmeira A; Fernandes MX; Sousa E; Pinto M; Inga A; Saraiva L
    Biochem Pharmacol; 2013 May; 85(9):1234-45. PubMed ID: 23428467
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Investigation of the MDM2-binding potential of de novo designed peptides using enhanced sampling simulations.
    Durojaye OA; Yekeen AA; Idris MO; Okoro NO; Odiba AS; Nwanguma BC
    Int J Biol Macromol; 2024 Jun; 269(Pt 2):131840. PubMed ID: 38679255
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting of p53 peptide analogues to anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy.
    Shin JS; Ha JH; Chi SW
    Biochem Biophys Res Commun; 2014 Jan; 443(3):882-7. PubMed ID: 24342622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR structure of a complex between MDM2 and a small molecule inhibitor.
    Fry DC; Emerson SD; Palme S; Vu BT; Liu CM; Podlaski F
    J Biomol NMR; 2004 Oct; 30(2):163-73. PubMed ID: 15557803
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX.
    Hu B; Gilkes DM; Chen J
    Cancer Res; 2007 Sep; 67(18):8810-7. PubMed ID: 17875722
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wild-type p53 breast cancer cells.
    Geng QQ; Dong DF; Chen NZ; Wu YY; Li EX; Wang J; Wang SM
    Int J Oncol; 2013 Dec; 43(6):1935-42. PubMed ID: 24126697
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer: in vitro and in vivo activities and mechanisms.
    Wang H; Nan L; Yu D; Agrawal S; Zhang R
    Clin Cancer Res; 2001 Nov; 7(11):3613-24. PubMed ID: 11705884
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.