BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 24830940)

  • 1. Long-term channel block is required to inhibit cellular transformation by human ether-à-go-go-related gene (hERG1) potassium channels.
    Pier DM; Shehatou GS; Giblett S; Pullar CE; Trezise DJ; Pritchard CA; Challiss RA; Mitcheson JS
    Mol Pharmacol; 2014 Aug; 86(2):211-21. PubMed ID: 24830940
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241.
    Gessner G; Heinemann SH
    Br J Pharmacol; 2003 Jan; 138(1):161-71. PubMed ID: 12522086
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Link between Inactivation and High-Affinity Block of hERG1 Channels.
    Wu W; Gardner A; Sanguinetti MC
    Mol Pharmacol; 2015 Jun; 87(6):1042-50. PubMed ID: 25855787
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of HERG1 K+ channel protein expression decreases cell proliferation of human small cell lung cancer cells.
    Glassmeier G; Hempel K; Wulfsen I; Bauer CK; Schumacher U; Schwarz JR
    Pflugers Arch; 2012 Feb; 463(2):365-76. PubMed ID: 22075718
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vivo targeting of ERG potassium channels in mice and dogs by a positron-emitting analogue of fluoroclofilium.
    Kim SW; Yang SD; Ahn BJ; Park JH; Lee DS; Gessner G; Heinemann SH; Herdering W; Yu KH
    Exp Mol Med; 2005 Aug; 37(4):269-75. PubMed ID: 16155403
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of HERG1 potassium channel in both malignant transformation and disease progression in head and neck carcinomas.
    Menéndez ST; Rodrigo JP; Alvarez-Teijeiro S; Villaronga MÁ; Allonca E; Vallina A; Astudillo A; Barros F; Suárez C; García-Pedrero JM
    Mod Pathol; 2012 Aug; 25(8):1069-78. PubMed ID: 22460808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling.
    Cherubini A; Hofmann G; Pillozzi S; Guasti L; Crociani O; Cilia E; Di Stefano P; Degani S; Balzi M; Olivotto M; Wanke E; Becchetti A; Defilippi P; Wymore R; Arcangeli A
    Mol Biol Cell; 2005 Jun; 16(6):2972-83. PubMed ID: 15800067
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chemotherapy resistance in acute lymphoblastic leukemia requires hERG1 channels and is overcome by hERG1 blockers.
    Pillozzi S; Masselli M; De Lorenzo E; Accordi B; Cilia E; Crociani O; Amedei A; Veltroni M; D'Amico M; Basso G; Becchetti A; Campana D; Arcangeli A
    Blood; 2011 Jan; 117(3):902-14. PubMed ID: 21048156
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined receptor and ligand-based approach to the universal pharmacophore model development for studies of drug blockade to the hERG1 pore domain.
    Durdagi S; Duff HJ; Noskov SY
    J Chem Inf Model; 2011 Feb; 51(2):463-74. PubMed ID: 21241063
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression.
    Becchetti A; Crescioli S; Zanieri F; Petroni G; Mercatelli R; Coppola S; Gasparoli L; D'Amico M; Pillozzi S; Crociani O; Stefanini M; Fiore A; Carraresi L; Morello V; Manoli S; Brizzi MF; Ricci D; Rinaldi M; Masi A; Schmidt T; Quercioli F; Defilippi P; Arcangeli A
    Sci Signal; 2017 Apr; 10(473):. PubMed ID: 28377405
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo.
    Zhao J; Wei XL; Jia YS; Zheng JQ
    Eur J Pharmacol; 2008 Jan; 579(1-3):50-7. PubMed ID: 17976575
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications.
    Menéndez ST; Villaronga MA; Rodrigo JP; Alvarez-Teijeiro S; García-Carracedo D; Urdinguio RG; Fraga MF; Pardo LA; Viloria CG; Suárez C; García-Pedrero JM
    J Mol Med (Berl); 2012 Oct; 90(10):1173-84. PubMed ID: 22466864
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Physical and functional interaction between integrins and hERG1 channels in cancer cells.
    Pillozzi S; Arcangeli A
    Adv Exp Med Biol; 2010; 674():55-67. PubMed ID: 20549940
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel.
    Wei X; Sun H; Yan H; Zhang C; Zhang S; Liu X; Hua N; Ma X; Zheng J
    Cancer Biol Ther; 2013 May; 14(5):450-7. PubMed ID: 23917377
    [TBL] [Abstract][Full Text] [Related]  

  • 15. State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy.
    Ganapathi SB; Kester M; Elmslie KS
    Am J Physiol Cell Physiol; 2009 Apr; 296(4):C701-10. PubMed ID: 19244476
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stoichiometry of altered hERG1 channel gating by small molecule activators.
    Wu W; Sachse FB; Gardner A; Sanguinetti MC
    J Gen Physiol; 2014 Apr; 143(4):499-512. PubMed ID: 24638994
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Colombian Scorpion
    Beltrán-Vidal J; Carcamo-Noriega E; Pastor N; Zamudio-Zuñiga F; Guerrero-Vargas JA; Castaño S; Possani LD; Restano-Cassulini R
    Toxins (Basel); 2021 Jun; 13(6):. PubMed ID: 34201318
    [TBL] [Abstract][Full Text] [Related]  

  • 18. hERG1 channels regulate VEGF-A secretion in human gastric cancer: clinicopathological correlations and therapeutical implications.
    Crociani O; Lastraioli E; Boni L; Pillozzi S; Romoli MR; D'Amico M; Stefanini M; Crescioli S; Masi A; Taddei A; Bencini L; Bernini M; Farsi M; Beghelli S; Scarpa A; Messerini L; Tomezzoli A; Vindigni C; Morgagni P; Saragoni L; Giommoni E; Gasperoni S; Di Costanzo F; Roviello F; De Manzoni G; Bechi P; Arcangeli A
    Clin Cancer Res; 2014 Mar; 20(6):1502-12. PubMed ID: 24449824
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cysteine 723 in the C-linker segment confers oxidative inhibition of hERG1 potassium channels.
    Kolbe K; Schönherr R; Gessner G; Sahoo N; Hoshi T; Heinemann SH
    J Physiol; 2010 Aug; 588(Pt 16):2999-3009. PubMed ID: 20547678
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of potassium channels in tumours of the gastrointestinal tract: a focus on the human ether-à-go-go related gene 1 channels.
    Arcangeli A; Duranti C; Iorio J; Lastraioli E
    J Physiol; 2023 May; 601(9):1597-1610. PubMed ID: 36215066
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.