376 related articles for article (PubMed ID: 24836077)
1. Inhibition of mitochondrial protein import by mutant huntingtin.
Yano H; Baranov SV; Baranova OV; Kim J; Pan Y; Yablonska S; Carlisle DL; Ferrante RJ; Kim AH; Friedlander RM
Nat Neurosci; 2014 Jun; 17(6):822-31. PubMed ID: 24836077
[TBL] [Abstract][Full Text] [Related]
2. Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
Shirendeb UP; Calkins MJ; Manczak M; Anekonda V; Dufour B; McBride JL; Mao P; Reddy PH
Hum Mol Genet; 2012 Jan; 21(2):406-20. PubMed ID: 21997870
[TBL] [Abstract][Full Text] [Related]
3. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking.
Orr AL; Li S; Wang CE; Li H; Wang J; Rong J; Xu X; Mastroberardino PG; Greenamyre JT; Li XJ
J Neurosci; 2008 Mar; 28(11):2783-92. PubMed ID: 18337408
[TBL] [Abstract][Full Text] [Related]
4. A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin.
Damiano M; Diguet E; Malgorn C; D'Aurelio M; Galvan L; Petit F; Benhaim L; Guillermier M; Houitte D; Dufour N; Hantraye P; Canals JM; Alberch J; Delzescaux T; Déglon N; Beal MF; Brouillet E
Hum Mol Genet; 2013 Oct; 22(19):3869-82. PubMed ID: 23720495
[TBL] [Abstract][Full Text] [Related]
5. Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.
Shirendeb U; Reddy AP; Manczak M; Calkins MJ; Mao P; Tagle DA; Reddy PH
Hum Mol Genet; 2011 Apr; 20(7):1438-55. PubMed ID: 21257639
[TBL] [Abstract][Full Text] [Related]
6. Effects of overexpression of huntingtin proteins on mitochondrial integrity.
Wang H; Lim PJ; Karbowski M; Monteiro MJ
Hum Mol Genet; 2009 Feb; 18(4):737-52. PubMed ID: 19039036
[TBL] [Abstract][Full Text] [Related]
7. Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) has a key role in the mitochondrial dysfunction induced by mutant huntingtin.
Sassone F; Margulets V; Maraschi A; Rodighiero S; Passafaro M; Silani V; Ciammola A; Kirshenbaum LA; Sassone J
Hum Mol Genet; 2015 Nov; 24(22):6530-9. PubMed ID: 26358776
[TBL] [Abstract][Full Text] [Related]
8. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.
Zhang H; Li Q; Graham RK; Slow E; Hayden MR; Bezprozvanny I
Neurobiol Dis; 2008 Jul; 31(1):80-8. PubMed ID: 18502655
[TBL] [Abstract][Full Text] [Related]
9. Mitochondria-targeted molecules MitoQ and SS31 reduce mutant huntingtin-induced mitochondrial toxicity and synaptic damage in Huntington's disease.
Yin X; Manczak M; Reddy PH
Hum Mol Genet; 2016 May; 25(9):1739-53. PubMed ID: 26908605
[TBL] [Abstract][Full Text] [Related]
10. The induction levels of heat shock protein 70 differentiate the vulnerabilities to mutant huntingtin among neuronal subtypes.
Tagawa K; Marubuchi S; Qi ML; Enokido Y; Tamura T; Inagaki R; Murata M; Kanazawa I; Wanker EE; Okazawa H
J Neurosci; 2007 Jan; 27(4):868-80. PubMed ID: 17251428
[TBL] [Abstract][Full Text] [Related]
11. Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability.
Fu Z; Liu F; Liu C; Jin B; Jiang Y; Tang M; Qi X; Guo X
Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1428-1435. PubMed ID: 30802639
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms for neuronal cell death and dysfunction in Huntington's disease: pathological cross-talk between the nucleus and the mitochondria?
Sawa A
J Mol Med (Berl); 2001 Jul; 79(7):375-81. PubMed ID: 11466559
[TBL] [Abstract][Full Text] [Related]
13. Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice.
Bradford J; Shin JY; Roberts M; Wang CE; Sheng G; Li S; Li XJ
J Biol Chem; 2010 Apr; 285(14):10653-61. PubMed ID: 20145253
[TBL] [Abstract][Full Text] [Related]
14. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).
Ratovitski T; Arbez N; Stewart JC; Chighladze E; Ross CA
Cell Cycle; 2015; 14(11):1716-29. PubMed ID: 25927346
[TBL] [Abstract][Full Text] [Related]
15. Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease.
Reddy PH; Shirendeb UP
Biochim Biophys Acta; 2012 Feb; 1822(2):101-10. PubMed ID: 22080977
[TBL] [Abstract][Full Text] [Related]
16. Mutant huntingtin disrupts mitochondrial proteostasis by interacting with TIM23.
Yablonska S; Ganesan V; Ferrando LM; Kim J; Pyzel A; Baranova OV; Khattar NK; Larkin TM; Baranov SV; Chen N; Strohlein CE; Stevens DA; Wang X; Chang YF; Schurdak ME; Carlisle DL; Minden JS; Friedlander RM
Proc Natl Acad Sci U S A; 2019 Aug; 116(33):16593-16602. PubMed ID: 31346086
[TBL] [Abstract][Full Text] [Related]
17. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation.
Wong YC; Holzbaur EL
J Neurosci; 2014 Jan; 34(4):1293-305. PubMed ID: 24453320
[TBL] [Abstract][Full Text] [Related]
18. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
Hermel E; Gafni J; Propp SS; Leavitt BR; Wellington CL; Young JE; Hackam AS; Logvinova AV; Peel AL; Chen SF; Hook V; Singaraja R; Krajewski S; Goldsmith PC; Ellerby HM; Hayden MR; Bredesen DE; Ellerby LM
Cell Death Differ; 2004 Apr; 11(4):424-38. PubMed ID: 14713958
[TBL] [Abstract][Full Text] [Related]
19. Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons.
Chang DT; Rintoul GL; Pandipati S; Reynolds IJ
Neurobiol Dis; 2006 May; 22(2):388-400. PubMed ID: 16473015
[TBL] [Abstract][Full Text] [Related]
20. Regulation of mitochondrial morphology and cell cycle by microRNA-214 targeting Mitofusin2.
Bucha S; Mukhopadhyay D; Bhattacharyya NP
Biochem Biophys Res Commun; 2015 Oct; 465(4):797-802. PubMed ID: 26307536
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]