BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 24842792)

  • 1. Human Sarcoma growth is sensitive to small-molecule mediated AXIN stabilization.
    De Robertis A; Mennillo F; Rossi M; Valensin S; Tunici P; Mori E; Caradonna N; Varrone M; Salerno M
    PLoS One; 2014; 9(5):e97847. PubMed ID: 24842792
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A small molecule compound 759 inhibits the wnt/beta-catenin signaling pathway via increasing the Axin protein stability.
    Sun S; Gong YD; Kang JS; Dong MS; Choi Y
    Med Oncol; 2024 May; 41(6):147. PubMed ID: 38733492
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells.
    De Robertis A; Valensin S; Rossi M; Tunici P; Verani M; De Rosa A; Giordano C; Varrone M; Nencini A; Pratelli C; Benicchi T; Bakker A; Hill J; Sangthongpitag K; Pendharkar V; Liu B; Ng FM; Then SW; Jing Tai S; Cheong SM; He X; Caricasole A; Salerno M
    Mol Cancer Ther; 2013 Jul; 12(7):1180-9. PubMed ID: 23619303
    [TBL] [Abstract][Full Text] [Related]  

  • 4. USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin.
    Ji L; Lu B; Zamponi R; Charlat O; Aversa R; Yang Z; Sigoillot F; Zhu X; Hu T; Reece-Hoyes JS; Russ C; Michaud G; Tchorz JS; Jiang X; Cong F
    Nat Commun; 2019 Sep; 10(1):4184. PubMed ID: 31519875
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transforming Growth Factor β Activation Primes Canonical Wnt Signaling Through Down-Regulation of Axin-2.
    Gillespie J; Ross RL; Corinaldesi C; Esteves F; Derrett-Smith E; McDermott MF; Doody GM; Denton CP; Emery P; Del Galdo F
    Arthritis Rheumatol; 2018 Jun; 70(6):932-942. PubMed ID: 29409120
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gtpbp2 is a positive regulator of Wnt signaling and maintains low levels of the Wnt negative regulator Axin.
    Gillis WQ; Kirmizitas A; Iwasaki Y; Ki DH; Wyrick JM; Thomsen GH
    Cell Commun Signal; 2016 Aug; 14(1):15. PubMed ID: 27484226
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells.
    Bao R; Christova T; Song S; Angers S; Yan X; Attisano L
    PLoS One; 2012; 7(11):e48670. PubMed ID: 23144924
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evidence for tankyrases as antineoplastic targets in lung cancer.
    Busch AM; Johnson KC; Stan RV; Sanglikar A; Ahmed Y; Dmitrovsky E; Freemantle SJ
    BMC Cancer; 2013 Apr; 13():211. PubMed ID: 23621985
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CCAAT/enhancer-binding protein-β functions as a negative regulator of Wnt/β-catenin signaling through activation of AXIN1 gene expression.
    Park S; Lee MS; Gwak J; Choi TI; Lee Y; Ju BG; Kim CH; Oh S
    Cell Death Dis; 2018 Oct; 9(10):1023. PubMed ID: 30283086
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Discovery and Characterization of K-756, a Novel Wnt/β-Catenin Pathway Inhibitor Targeting Tankyrase.
    Okada-Iwasaki R; Takahashi Y; Watanabe Y; Ishida H; Saito J; Nakai R; Asai A
    Mol Cancer Ther; 2016 Jul; 15(7):1525-34. PubMed ID: 27196752
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Disruption of TCF/β-Catenin Binding Impairs Wnt Signaling and Induces Apoptosis in Soft Tissue Sarcoma Cells.
    Martinez-Font E; Felipe-Abrio I; Calabuig-Fariñas S; Ramos R; Terrasa J; Vögler O; Alemany R; Martín-Broto J; Obrador-Hevia A
    Mol Cancer Ther; 2017 Jun; 16(6):1166-1176. PubMed ID: 28292937
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SS18-SSX fusion protein-induced Wnt/β-catenin signaling is a therapeutic target in synovial sarcoma.
    Trautmann M; Sievers E; Aretz S; Kindler D; Michels S; Friedrichs N; Renner M; Kirfel J; Steiner S; Huss S; Koch A; Penzel R; Larsson O; Kawai A; Tanaka S; Sonobe H; Waha A; Schirmacher P; Mechtersheimer G; Wardelmann E; Büttner R; Hartmann W
    Oncogene; 2014 Oct; 33(42):5006-16. PubMed ID: 24166495
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin Puncta.
    Martino-Echarri E; Brocardo MG; Mills KM; Henderson BR
    PLoS One; 2016; 11(3):e0150484. PubMed ID: 26930278
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
    Lau T; Chan E; Callow M; Waaler J; Boggs J; Blake RA; Magnuson S; Sambrone A; Schutten M; Firestein R; Machon O; Korinek V; Choo E; Diaz D; Merchant M; Polakis P; Holsworth DD; Krauss S; Costa M
    Cancer Res; 2013 May; 73(10):3132-44. PubMed ID: 23539443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Down-regulation of microRNA-31-5p inhibits proliferation and invasion of osteosarcoma cells through Wnt/β-catenin signaling pathway by enhancing AXIN1.
    Chen X; Zhong L; Li X; Liu W; Zhao Y; Li J
    Exp Mol Pathol; 2019 Jun; 108():32-41. PubMed ID: 30844369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Asymmetrically expressed axin required for anterior development in Tribolium.
    Fu J; Posnien N; Bolognesi R; Fischer TD; Rayl P; Oberhofer G; Kitzmann P; Brown SJ; Bucher G
    Proc Natl Acad Sci U S A; 2012 May; 109(20):7782-6. PubMed ID: 22552230
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase.
    Wang Z; Tacchelly-Benites O; Yang E; Thorne CA; Nojima H; Lee E; Ahmed Y
    Genetics; 2016 May; 203(1):269-81. PubMed ID: 26975665
    [TBL] [Abstract][Full Text] [Related]  

  • 18. WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway.
    Goto T; Matsuzawa J; Iemura S; Natsume T; Shibuya H
    FEBS Lett; 2016 May; 590(9):1291-303. PubMed ID: 27098453
    [TBL] [Abstract][Full Text] [Related]  

  • 19. AURKA governs self-renewal capacity in glioma-initiating cells via stabilization/activation of β-catenin/Wnt signaling.
    Xia Z; Wei P; Zhang H; Ding Z; Yang L; Huang Z; Zhang N
    Mol Cancer Res; 2013 Sep; 11(9):1101-11. PubMed ID: 23761169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. USP25 regulates Wnt signaling by controlling the stability of tankyrases.
    Xu D; Liu J; Fu T; Shan B; Qian L; Pan L; Yuan J
    Genes Dev; 2017 May; 31(10):1024-1035. PubMed ID: 28619731
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.