BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 24844227)

  • 1. Avidity-dependent programming of autoreactive T cells in T1D.
    Durinovic-Belló I; Gersuk VH; Ni C; Wu R; Thorpe J; Jospe N; Sanda S; Greenbaum CJ; Nepom GT
    PLoS One; 2014; 9(5):e98074. PubMed ID: 24844227
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin.
    Durinovic-Belló I; Wu RP; Gersuk VH; Sanda S; Shilling HG; Nepom GT
    Genes Immun; 2010 Mar; 11(2):188-93. PubMed ID: 20054344
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proinsulin C-peptide is an autoantigen in people with type 1 diabetes.
    So M; Elso CM; Tresoldi E; Pakusch M; Pathiraja V; Wentworth JM; Harrison LC; Krishnamurthy B; Thomas HE; Rodda C; Cameron FJ; McMahon J; Kay TWH; Mannering SI
    Proc Natl Acad Sci U S A; 2018 Oct; 115(42):10732-10737. PubMed ID: 30275329
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Autoimmune responses to the beta cell autoantigen, insulin, and the INS VNTR-IDDM2 locus.
    Sarugeri E; Dozio N; Belloni C; Meschi F; Pastore MR; Bonifacio E
    Clin Exp Immunol; 1998 Dec; 114(3):370-6. PubMed ID: 9844045
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes.
    Chen W; Bergerot I; Elliott JF; Harrison LC; Abiru N; Eisenbarth GS; Delovitch TL
    J Immunol; 2001 Nov; 167(9):4926-35. PubMed ID: 11673498
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Changes in autoreactive T cell avidity during type 1 diabetes development.
    Standifer NE; Burwell EA; Gersuk VH; Greenbaum CJ; Nepom GT
    Clin Immunol; 2009 Sep; 132(3):312-20. PubMed ID: 19482555
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Maternal Type 1 Diabetes Reduces Autoantigen-Responsive CD4
    Knoop J; Eugster A; Gavrisan A; Lickert R; Sedlmeier EM; Dietz S; Lindner A; Warncke K; Hummel N; Ziegler AG; Bonifacio E
    Diabetes; 2020 Apr; 69(4):661-669. PubMed ID: 31896551
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.
    Serreze DV; Holl TM; Marron MP; Graser RT; Johnson EA; Choisy-Rossi C; Slattery RM; Lieberman SM; DiLorenzo TP
    J Immunol; 2004 Jan; 172(2):871-9. PubMed ID: 14707058
    [TBL] [Abstract][Full Text] [Related]  

  • 9. T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading.
    Ott PA; Dittrich MT; Herzog BA; Guerkov R; Gottlieb PA; Putnam AL; Durinovic-Bello I; Boehm BO; Tary-Lehmann M; Lehmann PV
    J Clin Immunol; 2004 Jul; 24(4):327-39. PubMed ID: 15163889
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes.
    Michels AW; Landry LG; McDaniel KA; Yu L; Campbell-Thompson M; Kwok WW; Jones KL; Gottlieb PA; Kappler JW; Tang Q; Roep BO; Atkinson MA; Mathews CE; Nakayama M
    Diabetes; 2017 Mar; 66(3):722-734. PubMed ID: 27920090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity.
    Durinovic-Belló I; Boehm BO; Ziegler AG
    J Autoimmun; 2002 Feb; 18(1):55-66. PubMed ID: 11869047
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A TCR-like antibody against a proinsulin-containing fusion peptide ameliorates type 1 diabetes in NOD mice.
    Matsumoto Y; Kishida K; Matsumoto M; Matsuoka S; Kohyama M; Suenaga T; Arase H
    Biochem Biophys Res Commun; 2021 Jan; 534():680-686. PubMed ID: 33208230
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proinsulin-specific T regulatory cells may control immune responses in type 1 diabetes: implications for adoptive therapy.
    Gliwiński M; Iwaszkiewicz-Grześ D; Wołoszyn-Durkiewicz A; Tarnowska M; Żalińska M; Hennig M; Zielińska H; Dukat-Mazurek A; Zielkowska-Dębska J; Zieliński M; Jaźwińska-Curyłło A; Owczuk R; Jarosz-Chobot P; Bossowski A; Szadkowska A; Młynarski W; Marek-Trzonkowska N; Moszkowska G; Siebert J; Myśliwiec M; Trzonkowski P
    BMJ Open Diabetes Res Care; 2020 Feb; 8(1):. PubMed ID: 32098895
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Promiscuous binding of proinsulin peptides to Type 1 diabetes-permissive and -protective HLA class II molecules.
    Astill TP; Ellis RJ; Arif S; Tree TI; Peakman M
    Diabetologia; 2003 Apr; 46(4):496-503. PubMed ID: 12684749
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proinsulin: a unique autoantigen triggering autoimmune diabetes.
    You S; Chatenoud L
    J Clin Invest; 2006 Dec; 116(12):3108-10. PubMed ID: 17143326
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peripheral Proinsulin Expression Controls Low-Avidity Proinsulin-Reactive CD8 T Cells in Type 1 Diabetes.
    Thayer TC; Pearson JA; De Leenheer E; Hanna SJ; Boldison J; Davies J; Tsui A; Ahmed S; Easton P; Siew LK; Wen L; Wong FS
    Diabetes; 2016 Nov; 65(11):3429-3439. PubMed ID: 27495224
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Continuum model of T-cell avidity: Understanding autoreactive and regulatory T-cell responses in type 1 diabetes.
    Jaberi-Douraki M; Pietropaolo M; Khadra A
    J Theor Biol; 2015 Oct; 383():93-105. PubMed ID: 26271890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop for Standardization of T-cell assays in type 1 diabetes.
    Peakman M; Tree TI; Endl J; van Endert P; Atkinson MA; Roep BO;
    Diabetes; 2001 Aug; 50(8):1749-54. PubMed ID: 11473034
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DRB4*01:01 Has a Distinct Motif and Presents a Proinsulin Epitope That Is Recognized in Subjects with Type 1 Diabetes.
    James EA; Gillette L; Durinovic-Bello I; Speake C; Bondinas GP; Moustakas AK; Greenbaum CJ; Papadopoulos GK; Kwok WW
    J Immunol; 2018 Dec; 201(12):3524-3533. PubMed ID: 30455401
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of antigen specific T cells in diabetes - Lessons from pre-clinical studies and early clinical trials.
    Krishnamurthy B; Selck C; Chee J; Jhala G; Kay TW
    J Autoimmun; 2016 Jul; 71():35-43. PubMed ID: 27083395
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.