BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

747 related articles for article (PubMed ID: 24845216)

  • 1. Atomistic investigation of the effect of incremental modification of deoxyribose sugars by locked nucleic acid (β-D-LNA and α-L-LNA) moieties on the structures and thermodynamics of DNA-RNA hybrid duplexes.
    Suresh G; Priyakumar UD
    J Phys Chem B; 2014 Jun; 118(22):5853-63. PubMed ID: 24845216
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structures, dynamics, and stabilities of fully modified locked nucleic acid (β-D-LNA and α-L-LNA) duplexes in comparison to pure DNA and RNA duplexes.
    Suresh G; Priyakumar UD
    J Phys Chem B; 2013 May; 117(18):5556-64. PubMed ID: 23617391
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interplay of LNA and 2'-O-methyl RNA in the structure and thermodynamics of RNA hybrid systems: a molecular dynamics study using the revised AMBER force field and comparison with experimental results.
    Yildirim I; Kierzek E; Kierzek R; Schatz GC
    J Phys Chem B; 2014 Dec; 118(49):14177-87. PubMed ID: 25268896
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inclusion of methoxy groups inverts the thermodynamic stabilities of DNA-RNA hybrid duplexes: A molecular dynamics simulation study.
    Suresh G; Priyakumar UD
    J Mol Graph Model; 2015 Sep; 61():150-9. PubMed ID: 26254870
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NMR studies of fully modified locked nucleic acid (LNA) hybrids: solution structure of an LNA:RNA hybrid and characterization of an LNA:DNA hybrid.
    Nielsen KE; Rasmussen J; Kumar R; Wengel J; Jacobsen JP; Petersen M
    Bioconjug Chem; 2004; 15(3):449-57. PubMed ID: 15149171
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The structure of a mixed LNA/DNA:RNA duplex is driven by conformational coupling between LNA and deoxyribose residues as determined from 13C relaxation measurements.
    Nielsen KE; Spielmann HP
    J Am Chem Soc; 2005 Nov; 127(43):15273-82. PubMed ID: 16248670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insights into structure, dynamics and hydration of locked nucleic acid (LNA) strand-based duplexes from molecular dynamics simulations.
    Pande V; Nilsson L
    Nucleic Acids Res; 2008 Mar; 36(5):1508-16. PubMed ID: 18203740
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of LNA modifications on small molecule binding to nucleic acids.
    Marin V; Hansen HF; Koch T; Armitage BA
    J Biomol Struct Dyn; 2004 Jun; 21(6):841-50. PubMed ID: 15107006
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Free-radical ring closure to conformationally locked α-L-carba-LNAs and synthesis of their oligos: nuclease stability, target RNA specificity, and elicitation of RNase H.
    Li Q; Yuan F; Zhou C; Plashkevych O; Chattopadhyaya J
    J Org Chem; 2010 Sep; 75(18):6122-40. PubMed ID: 20738147
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural studies of LNA:RNA duplexes by NMR: conformations and implications for RNase H activity.
    Bondensgaard K; Petersen M; Singh SK; Rajwanshi VK; Kumar R; Wengel J; Jacobsen JP
    Chemistry; 2000 Aug; 6(15):2687-95. PubMed ID: 10985717
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of locked nucleic acid modifications on the thermal stability of noncanonical DNA structure.
    Bhattacharyya J; Maiti S; Muhuri S; Nakano S; Miyoshi D; Sugimoto N
    Biochemistry; 2011 Aug; 50(34):7414-25. PubMed ID: 21774551
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: conformational tuning and high-affinity recognition of DNA/RNA targets.
    Wengel J; Petersen M; Nielsen KE; Jensen GA; Håkansson AE; Kumar R; Sørensen MD; Rajwanshi VK; Bryld T; Jacobsen JP
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):389-96. PubMed ID: 11563053
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thermodynamic, counterion, and hydration effects for the incorporation of locked nucleic acid nucleotides into DNA duplexes.
    Kaur H; Arora A; Wengel J; Maiti S
    Biochemistry; 2006 Jun; 45(23):7347-55. PubMed ID: 16752924
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The conformations of locked nucleic acids (LNA).
    Petersen M; Nielsen CB; Nielsen KE; Jensen GA; Bondensgaard K; Singh SK; Rajwanshi VK; Koshkin AA; Dahl BM; Wengel J; Jacobsen JP
    J Mol Recognit; 2000; 13(1):44-53. PubMed ID: 10679896
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Determination of affinity constants of locked nucleic acid (LNA) and DNA duplex formation using label free sensor technology.
    Möhrle BP; Kumpf M; Gauglitz G
    Analyst; 2005 Dec; 130(12):1634-8. PubMed ID: 16284662
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thermodynamic, counterion and hydration effects for the incorporation of locked nucleic acid (LNA) nucleotides in duplex.
    Kaur H; Arora A; Wengel J; Maiti S
    Nucleic Acids Symp Ser (Oxf); 2008; (52):425-6. PubMed ID: 18776435
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Scaffolding along nucleic acid duplexes using 2'-amino-locked nucleic acids.
    Astakhova IK; Wengel J
    Acc Chem Res; 2014 Jun; 47(6):1768-77. PubMed ID: 24749544
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of the heat capacity change in understanding and modeling melting thermodynamics of complementary duplexes containing standard and nucleobase-modified LNA.
    Hughesman CB; Turner RF; Haynes CA
    Biochemistry; 2011 Jun; 50(23):5354-68. PubMed ID: 21548576
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of the thermodynamics and base-pair dynamics of a full LNA:DNA duplex and of the isosequential DNA:DNA duplex.
    Bruylants G; Boccongelli M; Snoussi K; Bartik K
    Biochemistry; 2009 Sep; 48(35):8473-82. PubMed ID: 19670874
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Conformation of formacetal and 3'-thioformacetal nucleotide linkers and stability of their antisense RNA.DNA hybrid duplexes.
    Rice JS; Gao X
    Biochemistry; 1997 Jan; 36(2):399-411. PubMed ID: 9003193
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 38.