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2. SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. Geng C; Kaochar S; Li M; Rajapakshe K; Fiskus W; Dong J; Foley C; Dong B; Zhang L; Kwon OJ; Shah SS; Bolaki M; Xin L; Ittmann M; O'Malley BW; Coarfa C; Mitsiades N Oncogene; 2017 Aug; 36(33):4767-4777. PubMed ID: 28414305 [TBL] [Abstract][Full Text] [Related]
3. c-Myb facilitates immune escape of esophageal adenocarcinoma cells through the miR-145-5p/SPOP/PD-L1 axis. Zhang L; Wang X; Li Y; Han J; Gao X; Li S; Wang F Clin Transl Med; 2021 Sep; 11(9):e464. PubMed ID: 34586738 [TBL] [Abstract][Full Text] [Related]
4. SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions. Jiang Q; Zheng N; Bu L; Zhang X; Zhang X; Wu Y; Su Y; Wang L; Zhang X; Ren S; Dai X; Wu D; Xie W; Wei W; Zhu Y; Guo J Mol Cancer; 2021 Aug; 20(1):100. PubMed ID: 34353330 [TBL] [Abstract][Full Text] [Related]
5. Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate. Bunce MW; Boronenkov IV; Anderson RA J Biol Chem; 2008 Mar; 283(13):8678-86. PubMed ID: 18218622 [TBL] [Abstract][Full Text] [Related]
6. SPOP suppresses testicular germ cell tumors progression through ubiquitination and degradation of DPPA2. Wang J; Zhuang H; Zhang H; Li Q; Cao X; Lin Z; Lin T; Chen X; Ni X; Yang J; Zhao Y; Shen L; Wang H; Zhu J; Ye M; Jin X Biochem Biophys Res Commun; 2021 Jun; 557():55-61. PubMed ID: 33862460 [TBL] [Abstract][Full Text] [Related]
7. Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover. Zhang P; Gao K; Jin X; Ma J; Peng J; Wumaier R; Tang Y; Zhang Y; An J; Yan Q; Dong Y; Huang H; Yu L; Wang C Cell Death Dis; 2015 Mar; 6(3):e1687. PubMed ID: 25766326 [TBL] [Abstract][Full Text] [Related]
8. Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Geng C; He B; Xu L; Barbieri CE; Eedunuri VK; Chew SA; Zimmermann M; Bond R; Shou J; Li C; Blattner M; Lonard DM; Demichelis F; Coarfa C; Rubin MA; Zhou P; O'Malley BW; Mitsiades N Proc Natl Acad Sci U S A; 2013 Apr; 110(17):6997-7002. PubMed ID: 23559371 [TBL] [Abstract][Full Text] [Related]
9. BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. Kwon JE; La M; Oh KH; Oh YM; Kim GR; Seol JH; Baek SH; Chiba T; Tanaka K; Bang OS; Joe CO; Chung CH J Biol Chem; 2006 May; 281(18):12664-72. PubMed ID: 16524876 [TBL] [Abstract][Full Text] [Related]
10. MiR-373 promotes proliferation and metastasis of oral squamous cell carcinoma by targeting SPOP. Zhang XJ; Jin Y; Song JL; Deng F Eur Rev Med Pharmacol Sci; 2019 Jun; 23(12):5270-5276. PubMed ID: 31298378 [TBL] [Abstract][Full Text] [Related]
11. Dysregulation of INF2-mediated mitochondrial fission in SPOP-mutated prostate cancer. Jin X; Wang J; Gao K; Zhang P; Yao L; Tang Y; Tang L; Ma J; Xiao J; Zhang E; Zhu J; Zhang B; Zhao SM; Li Y; Ren S; Huang H; Yu L; Wang C PLoS Genet; 2017 Apr; 13(4):e1006748. PubMed ID: 28448495 [TBL] [Abstract][Full Text] [Related]
12. Novel insights into the SPOP E3 ubiquitin ligase: From the regulation of molecular mechanisms to tumorigenesis. Li XM; Wu HL; Xia QD; Zhou P; Wang SG; Yu X; Hu J Biomed Pharmacother; 2022 May; 149():112882. PubMed ID: 35364375 [TBL] [Abstract][Full Text] [Related]
13. SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG. Tan P; Xu Y; Du Y; Wu L; Guo B; Huang S; Zhu J; Li B; Lin F; Yao L Cell Death Dis; 2019 Oct; 10(11):794. PubMed ID: 31624231 [TBL] [Abstract][Full Text] [Related]
14. Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase. Errington WJ; Khan MQ; Bueler SA; Rubinstein JL; Chakrabartty A; Privé GG Structure; 2012 Jul; 20(7):1141-53. PubMed ID: 22632832 [TBL] [Abstract][Full Text] [Related]
15. Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. Li C; Ao J; Fu J; Lee DF; Xu J; Lonard D; O'Malley BW Oncogene; 2011 Oct; 30(42):4350-64. PubMed ID: 21577200 [TBL] [Abstract][Full Text] [Related]
16. SPOP suppresses tumorigenesis by regulating Hedgehog/Gli2 signaling pathway in gastric cancer. Zeng C; Wang Y; Lu Q; Chen J; Zhang J; Liu T; Lv N; Luo S J Exp Clin Cancer Res; 2014 Sep; 33(1):75. PubMed ID: 25204354 [TBL] [Abstract][Full Text] [Related]
17. Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation. Wu F; Dai X; Gan W; Wan L; Li M; Mitsiades N; Wei W; Ding Q; Zhang J Cancer Lett; 2017 Jan; 385():207-214. PubMed ID: 27780719 [TBL] [Abstract][Full Text] [Related]
18. The emerging role of SPOP protein in tumorigenesis and cancer therapy. Song Y; Xu Y; Pan C; Yan L; Wang ZW; Zhu X Mol Cancer; 2020 Jan; 19(1):2. PubMed ID: 31901237 [TBL] [Abstract][Full Text] [Related]
19. Speckle-type POZ protein suppresses hepatocellular carcinoma cell migration and invasion via ubiquitin-dependent proteolysis of SUMO1/sentrin specific peptidase 7. Ji P; Liang S; Li P; Xie C; Li J; Zhang K; Zheng X; Feng M; Li Q; Jiao H; Chi X; Zhao W; Zhang S; Wang X Biochem Biophys Res Commun; 2018 Jul; 502(1):30-42. PubMed ID: 29777712 [TBL] [Abstract][Full Text] [Related]
20. Mutational and expressional analyses of SPOP, a candidate tumor suppressor gene, in prostate, gastric and colorectal cancers. Kim MS; Je EM; Oh JE; Yoo NJ; Lee SH APMIS; 2013 Jul; 121(7):626-33. PubMed ID: 23216165 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]