These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Constitutive activities in the thyrotropin receptor: regulation and significance. Kleinau G; Biebermann H Adv Pharmacol; 2014; 70():81-119. PubMed ID: 24931193 [TBL] [Abstract][Full Text] [Related]
3. Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas. Jaeschke H; Mueller S; Eszlinger M; Paschke R Clin Endocrinol (Oxf); 2010 Dec; 73(6):815-20. PubMed ID: 20846293 [TBL] [Abstract][Full Text] [Related]
4. Current standards, variations, and pitfalls for the determination of constitutive TSHR activity in vitro. Mueller S; Jaeschke H; Paschke R Methods Enzymol; 2010; 485():421-36. PubMed ID: 21050930 [TBL] [Abstract][Full Text] [Related]
5. A new phenotype of nongoitrous and nonautoimmune hyperthyroidism caused by a heterozygous thyrotropin receptor mutation in transmembrane helix 6. Winkler F; Kleinau G; Tarnow P; Rediger A; Grohmann L; Gaetjens I; Krause G; L'Allemand D; Grüters A; Krude H; Biebermann H J Clin Endocrinol Metab; 2010 Aug; 95(8):3605-10. PubMed ID: 20501679 [TBL] [Abstract][Full Text] [Related]
6. Shared sporadic and somatic thyrotropin receptor mutations display more active in vitro activities than familial thyrotropin receptor mutations. Lueblinghoff J; Eszlinger M; Jaeschke H; Mueller S; Bircan R; Gozu H; Sancak S; Akalin S; Paschke R Thyroid; 2011 Mar; 21(3):221-9. PubMed ID: 21190443 [TBL] [Abstract][Full Text] [Related]
7. New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR. Biebermann H; Winkler F; Handke D; Teichmann A; Gerling B; Cameron F; Eichhorst J; Grüters A; Wiesner B; Kühnen P; Krude H; Kleinau G J Clin Endocrinol Metab; 2012 Feb; 97(2):E228-32. PubMed ID: 22112806 [TBL] [Abstract][Full Text] [Related]
8. Comparative proteomic analysis to dissect differences in signal transduction in activating TSH receptor mutations in the thyroid. Krause K; Boisnard A; Ihling C; Ludgate M; Eszlinger M; Krohn K; Sinz A; Fuhrer D Int J Biochem Cell Biol; 2012 Feb; 44(2):290-301. PubMed ID: 22074661 [TBL] [Abstract][Full Text] [Related]
10. A newly discovered TSHR variant (L665F) associated with nonautoimmune hyperthyroidism in an Austrian family induces constitutive TSHR activation by steric repulsion between TM1 and TM7. Jaeschke H; Schaarschmidt J; Eszlinger M; Huth S; Puttinger R; Rittinger O; Meiler J; Paschke R J Clin Endocrinol Metab; 2014 Oct; 99(10):E2051-9. PubMed ID: 24947036 [TBL] [Abstract][Full Text] [Related]
11. Identification and evaluation of constitutively active thyroid stimulating hormone receptor mutations. Lado-Abeal J; Quisenberry LR; Castro-Piedras I Methods Enzymol; 2010; 484():375-95. PubMed ID: 21036242 [TBL] [Abstract][Full Text] [Related]
12. Severe congenital hyperthyroidism caused by a germ-line neo mutation in the extracellular portion of the thyrotropin receptor. Grüters A; Schöneberg T; Biebermann H; Krude H; Krohn HP; Dralle H; Gudermann T J Clin Endocrinol Metab; 1998 May; 83(5):1431-6. PubMed ID: 9589634 [TBL] [Abstract][Full Text] [Related]
13. Identification of a new thyrotropin receptor germline mutation (Leu629Phe) in a family with neonatal onset of autosomal dominant nonautoimmune hyperthyroidism. Führer D; Wonerow P; Willgerodt H; Paschke R J Clin Endocrinol Metab; 1997 Dec; 82(12):4234-8. PubMed ID: 9398746 [TBL] [Abstract][Full Text] [Related]
14. Thyrotropin receptor-associated diseases: from adenomata to Graves disease. Davies TF; Ando T; Lin RY; Tomer Y; Latif R J Clin Invest; 2005 Aug; 115(8):1972-83. PubMed ID: 16075037 [TBL] [Abstract][Full Text] [Related]
15. Constitutive activation of the thyroid-stimulating hormone receptor (TSHR) by mutating Ile691 in the cytoplasmic tail segment. Liu Z; Fan F; Xiao X; Sun Y PLoS One; 2011 Jan; 6(1):e16335. PubMed ID: 21283701 [TBL] [Abstract][Full Text] [Related]
16. A new silent germline mutation of the TSH receptor: coexpression in a hyperthyroid family member with a second activating somatic mutation. Gozu HI; Mueller S; Bircan R; Krohn K; Ekinci G; Yavuzer D; Sargin H; Sargin M; Ones T; Gezen C; Orbay E; Cirakoglu B; Paschke R Thyroid; 2008 May; 18(5):499-508. PubMed ID: 18466076 [TBL] [Abstract][Full Text] [Related]
17. Novel thyrotropin receptor germline mutation (Ile568Val) in a Saxonian family with hereditary nonautoimmune hyperthyroidism. Claus M; Maier J; Paschke R; Kujat C; Stumvoll M; Führer D Thyroid; 2005 Sep; 15(9):1089-94. PubMed ID: 16187920 [TBL] [Abstract][Full Text] [Related]
18. Hyperthyroidism and Papillary Thyroid Carcinoma in Thyrotropin Receptor D633H Mutant Mice. Jaeschke H; Undeutsch H; Patyra K; Löf C; Eszlinger M; Khalil M; Jännäri M; Makkonen K; Toppari J; Zhang FP; Poutanen M; Paschke R; Kero J Thyroid; 2018 Oct; 28(10):1372-1386. PubMed ID: 30132406 [TBL] [Abstract][Full Text] [Related]
19. Thyrotropin receptor mutations as a tool to understand thyrotropin receptor action. Wonerow P; Neumann S; Gudermann T; Paschke R J Mol Med (Berl); 2001 Dec; 79(12):707-21. PubMed ID: 11862314 [TBL] [Abstract][Full Text] [Related]
20. Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity. Neumann S; Krohn K; Chey S; Paschke R Horm Metab Res; 2001 May; 33(5):263-9. PubMed ID: 11440271 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]