These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 2485065)

  • 1. Crystallographic studies of reduced bond inhibitors complexed with an aspartic proteinase.
    Foundling SI; Cooper J; Watson FE; Pearl LH; Hemmings A; Wood SP; Blundell T; Hallett A; Jones DM; Sueiras J
    J Cardiovasc Pharmacol; 1987; 10 Suppl 7():S59-68. PubMed ID: 2485065
    [TBL] [Abstract][Full Text] [Related]  

  • 2. X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen.
    Dealwis CG; Frazao C; Badasso M; Cooper JB; Tickle IJ; Driessen H; Blundell TL; Murakami K; Miyazaki H; Sueiras-Diaz J
    J Mol Biol; 1994 Feb; 236(1):342-60. PubMed ID: 8107115
    [TBL] [Abstract][Full Text] [Related]  

  • 3. X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution.
    Veerapandian B; Cooper JB; Sali A; Blundell TL
    J Mol Biol; 1990 Dec; 216(4):1017-29. PubMed ID: 2266553
    [TBL] [Abstract][Full Text] [Related]  

  • 4. X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin.
    Bailey D; Cooper JB; Veerapandian B; Blundell TL; Atrash B; Jones DM; Szelke M
    Biochem J; 1993 Jan; 289 ( Pt 2)(Pt 2):363-71. PubMed ID: 8424781
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, structure-activity, and molecular modeling studies of potent renin inhibitory peptides having N-terminal Nin-For-Trp (Ftr): angiotensinogen congeners modified by P1-P1' Phe-Phe, Sta, Leu psi[CH(OH)CH2]Val or leu psi[CH2NH]Val substitutions.
    Sawyer TK; Pals DT; Mao B; Staples DJ; de Vaux AE; Maggiora LL; Affholter JA; Kati W; Duchamp D; Hester JB
    J Med Chem; 1988 Jan; 31(1):18-30. PubMed ID: 3275777
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes.
    Foundling SI; Cooper J; Watson FE; Cleasby A; Pearl LH; Sibanda BL; Hemmings A; Wood SP; Blundell TL; Valler MJ
    Nature; 1987 May 28-Jun 3; 327(6120):349-52. PubMed ID: 3295561
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The His-Pro-Phe motif of angiotensinogen is a crucial determinant of the substrate specificity of renin.
    Nakagawa T; Akaki J; Satou R; Takaya M; Iwata H; Katsurada A; Nishiuchi K; Ohmura Y; Suzuki F; Nakamura Y
    Biol Chem; 2007 Feb; 388(2):237-46. PubMed ID: 17261087
    [TBL] [Abstract][Full Text] [Related]  

  • 8. X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor.
    Swain AL; Miller MM; Green J; Rich DH; Schneider J; Kent SB; Wlodawer A
    Proc Natl Acad Sci U S A; 1990 Nov; 87(22):8805-9. PubMed ID: 2247451
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New renin inhibitors containing novel analogues of statine.
    Jones DM; Sueiras-Diaz J; Szelke M; Leckie BJ; Beattie SR; Morton J; Neidle S; Kuroda R
    J Pept Res; 1997 Aug; 50(2):109-21. PubMed ID: 9273895
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent in vivo inhibitors of rat renin: analogues of human and rat angiotensinogen sequences containing different classes of pseudodipeptides at the scissile site.
    Sueiras-Diaz J; Jones DM; Szelke M; Leckie BJ; Beattie SR; Beattie C; Morton JJ
    J Pept Res; 1997 Oct; 50(4):239-47. PubMed ID: 9352462
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A neutron Laue diffraction study of endothiapepsin: implications for the aspartic proteinase mechanism.
    Coates L; Erskine PT; Wood SP; Myles DA; Cooper JB
    Biochemistry; 2001 Nov; 40(44):13149-57. PubMed ID: 11683623
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Renin inhibitors. Synthesis of transition-state analogue inhibitors containing phosphorus acid derivatives at the scissile bond.
    Allen MC; Fuhrer W; Tuck B; Wade R; Wood JM
    J Med Chem; 1989 Jul; 32(7):1652-61. PubMed ID: 2661820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. On the specificity of human renin. Studies with peptide inhibitors.
    Poulsen K; Haber E; Burton J
    Biochim Biophys Acta; 1976 Dec; 452(2):533-7. PubMed ID: 1009126
    [TBL] [Abstract][Full Text] [Related]  

  • 14. X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors.
    Cooper J; Quail W; Frazao C; Foundling SI; Blundell TL; Humblet C; Lunney EA; Lowther WT; Dunn BM
    Biochemistry; 1992 Sep; 31(35):8142-50. PubMed ID: 1525155
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Direct observation by X-ray analysis of the tetrahedral "intermediate" of aspartic proteinases.
    Veerapandian B; Cooper JB; Sali A; Blundell TL; Rosati RL; Dominy BW; Damon DB; Hoover DJ
    Protein Sci; 1992 Mar; 1(3):322-8. PubMed ID: 1304340
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Renin cleavage of a human kidney renin substrate analogous to human angiotensinogen, H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Ser-OH, that is human renin specific and is resistant to cathepsin D.
    Poe M; Wu JK; Lin TY; Hoogsteen K; Bull HG; Slater EE
    Anal Biochem; 1984 Aug; 140(2):459-67. PubMed ID: 6385771
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIV protease (HIV PR) inhibitor structure-activity-selectivity, and active site molecular modeling of high affinity Leu [CH(OH)CH2]Val modified viral and nonviral substrate analogs.
    Sawyer TK; Staples DJ; Liu L; Tomasselli AG; Hui JO; O'Connell K; Schostarez H; Hester JB; Moon J; Howe WJ
    Int J Pept Protein Res; 1992; 40(3-4):274-81. PubMed ID: 1478785
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity.
    Pereira PJ; Wang ZM; Rubin H; Huber R; Bode W; Schechter NM; Strobl S
    J Mol Biol; 1999 Feb; 286(1):163-73. PubMed ID: 9931257
    [TBL] [Abstract][Full Text] [Related]  

  • 19. X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
    Cronin NB; Badasso MO; J Tickle I; Dreyer T; Hoover DJ; Rosati RL; Humblet CC; Lunney EA; Cooper JB
    J Mol Biol; 2000 Nov; 303(5):745-60. PubMed ID: 11061973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins.
    Dhanaraj V; Dealwis CG; Frazao C; Badasso M; Sibanda BL; Tickle IJ; Cooper JB; Driessen HP; Newman M; Aguilar C
    Nature; 1992 Jun; 357(6378):466-72. PubMed ID: 1608447
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.