These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 2485071)

  • 1. Models for the three-dimensional structure of renin inhibitors bound in the active site of human renin: an analysis of the properties that produce tight binding.
    Carlson WD; Handschumacher M; Summers N; Karplus M; Haber E
    J Cardiovasc Pharmacol; 1987; 10 Suppl 7():S91-3. PubMed ID: 2485071
    [TBL] [Abstract][Full Text] [Related]  

  • 2. X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen.
    Dealwis CG; Frazao C; Badasso M; Cooper JB; Tickle IJ; Driessen H; Blundell TL; Murakami K; Miyazaki H; Sueiras-Diaz J
    J Mol Biol; 1994 Feb; 236(1):342-60. PubMed ID: 8107115
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystallographic studies of reduced bond inhibitors complexed with an aspartic proteinase.
    Foundling SI; Cooper J; Watson FE; Pearl LH; Hemmings A; Wood SP; Blundell T; Hallett A; Jones DM; Sueiras J
    J Cardiovasc Pharmacol; 1987; 10 Suppl 7():S59-68. PubMed ID: 2485065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution.
    Veerapandian B; Cooper JB; Sali A; Blundell TL
    J Mol Biol; 1990 Dec; 216(4):1017-29. PubMed ID: 2266553
    [TBL] [Abstract][Full Text] [Related]  

  • 5. X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
    Cronin NB; Badasso MO; J Tickle I; Dreyer T; Hoover DJ; Rosati RL; Humblet CC; Lunney EA; Cooper JB
    J Mol Biol; 2000 Nov; 303(5):745-60. PubMed ID: 11061973
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structures of complexes of rhizopuspepsin with pepstatin and other statine-containing inhibitors.
    Suguna K; Padlan EA; Bott R; Boger J; Parris KD; Davies DR
    Proteins; 1992 Jul; 13(3):195-205. PubMed ID: 1603809
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Construction of a model for the three-dimensional structure of human renal renin.
    Carlson W; Karplus M; Haber E
    Hypertension; 1985; 7(1):13-26. PubMed ID: 3884498
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Orally potent human renin inhibitors derived from angiotensinogen transition state: design, synthesis, and mode of interaction.
    Iizuka K; Kamijo T; Harada H; Akahane K; Kubota T; Umeyama H; Ishida T; Kiso Y
    J Med Chem; 1990 Oct; 33(10):2707-14. PubMed ID: 2120440
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Three-dimensional structure of human renin.
    Akahane K; Umeyama H; Nakagawa S; Moriguchi I; Hirose S; Iizuka K; Murakami K
    Hypertension; 1985; 7(1):3-12. PubMed ID: 3884499
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Renin inhibitors: a search for principles of design.
    Haber E; Hui KY; Carlson WD; Bernatowicz MS
    J Cardiovasc Pharmacol; 1987; 10 Suppl 7():S54-8. PubMed ID: 2485064
    [TBL] [Abstract][Full Text] [Related]  

  • 11. X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins.
    Dhanaraj V; Dealwis CG; Frazao C; Badasso M; Sibanda BL; Tickle IJ; Cooper JB; Driessen HP; Newman M; Aguilar C
    Nature; 1992 Jun; 357(6378):466-72. PubMed ID: 1608447
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High resolution crystal structures of recombinant human renin in complex with polyhydroxymonoamide inhibitors.
    Tong L; Pav S; Lamarre D; Pilote L; LaPlante S; Anderson PC; Jung G
    J Mol Biol; 1995 Jul; 250(2):211-22. PubMed ID: 7608971
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The renin-angiotensin system: an example of the study of linear peptides by x-ray crystallography.
    Precigoux G; Benkoulouche M; Geoffre S
    Biopolymers; 1989 Jan; 28(1):41-9. PubMed ID: 2655734
    [TBL] [Abstract][Full Text] [Related]  

  • 14. X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin.
    Bailey D; Cooper JB; Veerapandian B; Blundell TL; Atrash B; Jones DM; Szelke M
    Biochem J; 1993 Jan; 289 ( Pt 2)(Pt 2):363-71. PubMed ID: 8424781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The crystal structures of recombinant glycosylated human renin alone and in complex with a transition state analog inhibitor.
    Rahuel J; Priestle JP; Grütter MG
    J Struct Biol; 1991 Dec; 107(3):227-36. PubMed ID: 1807356
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Renin inhibitor SC-51106 complexed with human renin: discovery of a new binding site adjacent to P3.
    Hanson GJ; Clare M; Summers NL; Lim LW; Neidhart DJ; Shieh HS; Stevens AM
    Bioorg Med Chem; 1994 Sep; 2(9):909-18. PubMed ID: 7712126
    [TBL] [Abstract][Full Text] [Related]  

  • 17. X-ray analysis of a difluorostatone renin inhibitor bound as the tetrahedral hydrate to the aspartic protease endothiapepsin.
    Hoover DJ; Veerapandian B; Cooper JB; Damon DB; Dominy BW; Rosati RL; Blundell TL
    Adv Exp Med Biol; 1991; 306():269-73. PubMed ID: 1812716
    [No Abstract]   [Full Text] [Related]  

  • 18. Renin inhibitors containing conformationally restricted P1-P1' dipeptide mimetics.
    Williams PD; Perlow DS; Payne LS; Holloway MK; Siegl PK; Schorn TW; Lynch RJ; Doyle JJ; Strouse JF; Vlasuk GP
    J Med Chem; 1991 Mar; 34(3):887-900. PubMed ID: 2002469
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The discovery of novel potent trans-3,4-disubstituted pyrrolidine inhibitors of the human aspartic protease renin from in silico three-dimensional (3D) pharmacophore searches.
    Lorthiois E; Breitenstein W; Cumin F; Ehrhardt C; Francotte E; Jacoby E; Ostermann N; Sellner H; Kosaka T; Webb RL; Rigel DF; Hassiepen U; Richert P; Wagner T; Maibaum J
    J Med Chem; 2013 Mar; 56(6):2207-17. PubMed ID: 23425156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery and optimization of a new class of potent and non-chiral indole-3-carboxamide-based renin inhibitors.
    Scheiper B; Matter H; Steinhagen H; Stilz U; Böcskei Z; Fleury V; McCort G
    Bioorg Med Chem Lett; 2010 Nov; 20(21):6268-72. PubMed ID: 20850300
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.