190 related articles for article (PubMed ID: 24850787)
1. Design, synthesis, and biological evaluation of 1,3-diarylpropenones as dual inhibitors of HIV-1 reverse transcriptase.
Meleddu R; Cannas V; Distinto S; Sarais G; Del Vecchio C; Esposito F; Bianco G; Corona A; Cottiglia F; Alcaro S; Parolin C; Artese A; Scalise D; Fresta M; Arridu A; Ortuso F; Maccioni E; Tramontano E
ChemMedChem; 2014 Aug; 9(8):1869-79. PubMed ID: 24850787
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.
Corona A; Onnis V; Deplano A; Bianco G; Demurtas M; Distinto S; Cheng YC; Alcaro S; Esposito F; Tramontano E
Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28859311
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.
Borkow G; Fletcher RS; Barnard J; Arion D; Motakis D; Dmitrienko GI; Parniak MA
Biochemistry; 1997 Mar; 36(11):3179-85. PubMed ID: 9115994
[TBL] [Abstract][Full Text] [Related]
4. (3Z)-3-(2-[4-(aryl)-1,3-thiazol-2-yl]hydrazin-1-ylidene)-2,3-dihydro-1H-indol-2-one derivatives as dual inhibitors of HIV-1 reverse transcriptase.
Meleddu R; Distinto S; Corona A; Bianco G; Cannas V; Esposito F; Artese A; Alcaro S; Matyus P; Bogdan D; Cottiglia F; Tramontano E; Maccioni E
Eur J Med Chem; 2015 Mar; 93():452-60. PubMed ID: 25728026
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1,3-diones: dual inhibition against HIV reverse transcriptase-associated RNase H and polymerase with antiviral activities.
Vernekar SK; Liu Z; Nagy E; Miller L; Kirby KA; Wilson DJ; Kankanala J; Sarafianos SG; Parniak MA; Wang Z
J Med Chem; 2015 Jan; 58(2):651-64. PubMed ID: 25522204
[TBL] [Abstract][Full Text] [Related]
6. Dissecting the effects of DNA polymerase and ribonuclease H inhibitor combinations on HIV-1 reverse-transcriptase activities.
Shaw-Reid CA; Feuston B; Munshi V; Getty K; Krueger J; Hazuda DJ; Parniak MA; Miller MD; Lewis D
Biochemistry; 2005 Feb; 44(5):1595-606. PubMed ID: 15683243
[TBL] [Abstract][Full Text] [Related]
7. Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase.
Yanagita H; Urano E; Matsumoto K; Ichikawa R; Takaesu Y; Ogata M; Murakami T; Wu H; Chiba J; Komano J; Hoshino T
Bioorg Med Chem; 2011 Jan; 19(2):816-25. PubMed ID: 21193314
[TBL] [Abstract][Full Text] [Related]
8. Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.
Corona A; Meleddu R; Esposito F; Distinto S; Bianco G; Masaoka T; Maccioni E; Menéndez-Arias L; Alcaro S; Le Grice SF; Tramontano E
PLoS One; 2016; 11(1):e0147225. PubMed ID: 26800261
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase.
Tang J; Vernekar SKV; Chen YL; Miller L; Huber AD; Myshakina N; Sarafianos SG; Parniak MA; Wang Z
Eur J Med Chem; 2017 Jun; 133():85-96. PubMed ID: 28384548
[TBL] [Abstract][Full Text] [Related]
10. Transient kinetic analyses of the ribonuclease H cleavage activity of HIV-1 reverse transcriptase in complex with efavirenz and/or a β-thujaplicinol analogue.
Herman BD; Sluis-Cremer N
Biochem J; 2013 Oct; 455(2):179-84. PubMed ID: 23927736
[TBL] [Abstract][Full Text] [Related]
11. Structure-activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain.
Cuzzucoli Crucitti G; Métifiot M; Pescatori L; Messore A; Madia VN; Pupo G; Saccoliti F; Scipione L; Tortorella S; Esposito F; Corona A; Cadeddu M; Marchand C; Pommier Y; Tramontano E; Costi R; Di Santo R
J Med Chem; 2015 Feb; 58(4):1915-28. PubMed ID: 25629256
[TBL] [Abstract][Full Text] [Related]
12. Alizarine derivatives as new dual inhibitors of the HIV-1 reverse transcriptase-associated DNA polymerase and RNase H activities effective also on the RNase H activity of non-nucleoside resistant reverse transcriptases.
Esposito F; Kharlamova T; Distinto S; Zinzula L; Cheng YC; Dutschman G; Floris G; Markt P; Corona A; Tramontano E
FEBS J; 2011 May; 278(9):1444-57. PubMed ID: 21348941
[TBL] [Abstract][Full Text] [Related]
13. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
[TBL] [Abstract][Full Text] [Related]
14. Novel piperidinylamino-diarylpyrimidine derivatives with dual structural conformations as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
Chen X; Liu X; Meng Q; Wang D; Liu H; De Clercq E; Pannecouque C; Balzarini J; Liu X
Bioorg Med Chem Lett; 2013 Dec; 23(24):6593-7. PubMed ID: 24239481
[TBL] [Abstract][Full Text] [Related]
15. Design and synthesis of N₁-aryl-benzimidazoles 2-substituted as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
Monforte AM; Ferro S; De Luca L; Lo Surdo G; Morreale F; Pannecouque C; Balzarini J; Chimirri A
Bioorg Med Chem; 2014 Feb; 22(4):1459-67. PubMed ID: 24457088
[TBL] [Abstract][Full Text] [Related]
16. Identification of HIV-1 reverse transcriptase dual inhibitors by a combined shape-, 2D-fingerprint- and pharmacophore-based virtual screening approach.
Distinto S; Esposito F; Kirchmair J; Cardia MC; Gaspari M; Maccioni E; Alcaro S; Markt P; Wolber G; Zinzula L; Tramontano E
Eur J Med Chem; 2012 Apr; 50():216-29. PubMed ID: 22361685
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, biological activity and docking study of imidazol-5-one as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Mokale SN; Lokwani D; Shinde DB
Bioorg Med Chem; 2012 May; 20(9):3119-27. PubMed ID: 22480850
[TBL] [Abstract][Full Text] [Related]
18. Molecular modeling, synthesis and biological evaluation of N-heteroaryl compounds as reverse transcriptase inhibitors against HIV-1.
Singh A; Yadav D; Yadav M; Dhamanage A; Kulkarni S; Singh RK
Chem Biol Drug Des; 2015 Mar; 85(3):336-47. PubMed ID: 25055732
[TBL] [Abstract][Full Text] [Related]
19. 3-Hydroxypyrimidine-2,4-diones as Selective Active Site Inhibitors of HIV Reverse Transcriptase-Associated RNase H: Design, Synthesis, and Biochemical Evaluations.
Tang J; Liu F; Nagy E; Miller L; Kirby KA; Wilson DJ; Wu B; Sarafianos SG; Parniak MA; Wang Z
J Med Chem; 2016 Mar; 59(6):2648-59. PubMed ID: 26927866
[TBL] [Abstract][Full Text] [Related]
20. 5-Hydroxypyrido[2,3-b]pyrazin-6(5H)-one derivatives as novel dual inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H and integrase.
Sun L; Gao P; Dong G; Zhang X; Cheng X; Ding X; Wang X; Daelemans D; De Clercq E; Pannecouque C; Menéndez-Arias L; Zhan P; Liu X
Eur J Med Chem; 2018 Jul; 155():714-724. PubMed ID: 29940462
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
