BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 24853937)

  • 1. Loss-of-function variants in schizophrenia risk and SETD1A as a candidate susceptibility gene.
    Takata A; Xu B; Ionita-Laza I; Roos JL; Gogos JA; Karayiorgou M
    Neuron; 2014 May; 82(4):773-80. PubMed ID: 24853937
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.
    Singh T; Kurki MI; Curtis D; Purcell SM; Crooks L; McRae J; Suvisaari J; Chheda H; Blackwood D; Breen G; Pietiläinen O; Gerety SS; Ayub M; Blyth M; Cole T; Collier D; Coomber EL; Craddock N; Daly MJ; Danesh J; DiForti M; Foster A; Freimer NB; Geschwind D; Johnstone M; Joss S; Kirov G; Körkkö J; Kuismin O; Holmans P; Hultman CM; Iyegbe C; Lönnqvist J; Männikkö M; McCarroll SA; McGuffin P; McIntosh AM; McQuillin A; Moilanen JS; Moore C; Murray RM; Newbury-Ecob R; Ouwehand W; Paunio T; Prigmore E; Rees E; Roberts D; Sambrook J; Sklar P; St Clair D; Veijola J; Walters JT; Williams H; ; ; ; ; Sullivan PF; Hurles ME; O'Donovan MC; Palotie A; Owen MJ; Barrett JC
    Nat Neurosci; 2016 Apr; 19(4):571-7. PubMed ID: 26974950
    [TBL] [Abstract][Full Text] [Related]  

  • 3. De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia.
    Takata A; Ionita-Laza I; Gogos JA; Xu B; Karayiorgou M
    Neuron; 2016 Mar; 89(5):940-7. PubMed ID: 26938441
    [TBL] [Abstract][Full Text] [Related]  

  • 4. De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia.
    Rees E; Han J; Morgan J; Carrera N; Escott-Price V; Pocklington AJ; Duffield M; Hall LS; Legge SE; Pardiñas AF; Richards AL; Roth J; Lezheiko T; Kondratyev N; Kaleda V; Golimbet V; Parellada M; González-Peñas J; Arango C; ; Gawlik M; Kirov G; Walters JTR; Holmans P; O'Donovan MC; Owen MJ
    Nat Neurosci; 2020 Feb; 23(2):179-184. PubMed ID: 31932766
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exome sequencing for bipolar disorder points to roles of de novo loss-of-function and protein-altering mutations.
    Kataoka M; Matoba N; Sawada T; Kazuno AA; Ishiwata M; Fujii K; Matsuo K; Takata A; Kato T
    Mol Psychiatry; 2016 Jul; 21(7):885-93. PubMed ID: 27217147
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel missense SETD1A variants in Japanese patients with schizophrenia: Resequencing and association analysis.
    Morikawa R; Watanabe Y; Igeta H; Arta RK; Ikeda M; Okazaki S; Hoya S; Saito T; Otsuka I; Egawa J; Tanifuji T; Iwata N; Someya T
    Psychiatry Res; 2022 Apr; 310():114481. PubMed ID: 35235885
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway.
    Wang S; Rhijn JV; Akkouh I; Kogo N; Maas N; Bleeck A; Ortiz IS; Lewerissa E; Wu KM; Schoenmaker C; Djurovic S; van Bokhoven H; Kleefstra T; Nadif Kasri N; Schubert D
    Cell Rep; 2022 May; 39(5):110790. PubMed ID: 35508131
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Integrated model of de novo and inherited genetic variants yields greater power to identify risk genes.
    He X; Sanders SJ; Liu L; De Rubeis S; Lim ET; Sutcliffe JS; Schellenberg GD; Gibbs RA; Daly MJ; Buxbaum JD; State MW; Devlin B; Roeder K
    PLoS Genet; 2013; 9(8):e1003671. PubMed ID: 23966865
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Refining the role of de novo protein-truncating variants in neurodevelopmental disorders by using population reference samples.
    Kosmicki JA; Samocha KE; Howrigan DP; Sanders SJ; Slowikowski K; Lek M; Karczewski KJ; Cutler DJ; Devlin B; Roeder K; Buxbaum JD; Neale BM; MacArthur DG; Wall DP; Robinson EB; Daly MJ
    Nat Genet; 2017 Apr; 49(4):504-510. PubMed ID: 28191890
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exome sequencing in obsessive-compulsive disorder reveals a burden of rare damaging coding variants.
    Halvorsen M; Samuels J; Wang Y; Greenberg BD; Fyer AJ; McCracken JT; Geller DA; Knowles JA; Zoghbi AW; Pottinger TD; Grados MA; Riddle MA; Bienvenu OJ; Nestadt PS; Krasnow J; Goes FS; Maher B; Nestadt G; Goldstein DB
    Nat Neurosci; 2021 Aug; 24(8):1071-1076. PubMed ID: 34183866
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice.
    Mukai J; Cannavò E; Crabtree GW; Sun Z; Diamantopoulou A; Thakur P; Chang CY; Cai Y; Lomvardas S; Takata A; Xu B; Gogos JA
    Neuron; 2019 Nov; 104(3):471-487.e12. PubMed ID: 31606247
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Setd1a Insufficiency in Mice Attenuates Excitatory Synaptic Function and Recapitulates Schizophrenia-Related Behavioral Abnormalities.
    Nagahama K; Sakoori K; Watanabe T; Kishi Y; Kawaji K; Koebis M; Nakao K; Gotoh Y; Aiba A; Uesaka N; Kano M
    Cell Rep; 2020 Sep; 32(11):108126. PubMed ID: 32937141
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Developmental disruption to the cortical transcriptome and synaptosome in a model of SETD1A loss-of-function.
    Clifton NE; Bosworth ML; Haan N; Rees E; Holmans PA; Wilkinson LS; Isles AR; Collins MO; Hall J
    Hum Mol Genet; 2022 Sep; 31(18):3095-3106. PubMed ID: 35531971
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutation screening of SCN2A in schizophrenia and identification of a novel loss-of-function mutation.
    Carroll LS; Woolf R; Ibrahim Y; Williams HJ; Dwyer S; Walters J; Kirov G; O'Donovan MC; Owen MJ
    Psychiatr Genet; 2016 Apr; 26(2):60-5. PubMed ID: 26555645
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome.
    Kummeling J; Stremmelaar DE; Raun N; Reijnders MRF; Willemsen MH; Ruiterkamp-Versteeg M; Schepens M; Man CCO; Gilissen C; Cho MT; McWalter K; Sinnema M; Wheless JW; Simon MEH; Genetti CA; Casey AM; Terhal PA; van der Smagt JJ; van Gassen KLI; Joset P; Bahr A; Steindl K; Rauch A; Keller E; Raas-Rothschild A; Koolen DA; Agrawal PB; Hoffman TL; Powell-Hamilton NN; Thiffault I; Engleman K; Zhou D; Bodamer O; Hoefele J; Riedhammer KM; Schwaibold EMC; Tasic V; Schubert D; Top D; Pfundt R; Higgs MR; Kramer JM; Kleefstra T
    Mol Psychiatry; 2021 Jun; 26(6):2013-2024. PubMed ID: 32346159
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Exome Sequencing of Familial Bipolar Disorder.
    Goes FS; Pirooznia M; Parla JS; Kramer M; Ghiban E; Mavruk S; Chen YC; Monson ET; Willour VL; Karchin R; Flickinger M; Locke AE; Levy SE; Scott LJ; Boehnke M; Stahl E; Moran JL; Hultman CM; Landén M; Purcell SM; Sklar P; Zandi PP; McCombie WR; Potash JB
    JAMA Psychiatry; 2016 Jun; 73(6):590-7. PubMed ID: 27120077
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database.
    Li J; Cai T; Jiang Y; Chen H; He X; Chen C; Li X; Shao Q; Ran X; Li Z; Xia K; Liu C; Sun ZS; Wu J
    Mol Psychiatry; 2016 Feb; 21(2):290-7. PubMed ID: 25849321
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia.
    Rees E; Kirov G; Walters JT; Richards AL; Howrigan D; Kavanagh DH; Pocklington AJ; Fromer M; Ruderfer DM; Georgieva L; Carrera N; Gormley P; Palta P; Williams H; Dwyer S; Johnson JS; Roussos P; Barker DD; Banks E; Milanova V; Rose SA; Chambert K; Mahajan M; Scolnick EM; Moran JL; Tsuang MT; Glatt SJ; Chen WJ; Hwu HG; ; Neale BM; Palotie A; Sklar P; Purcell SM; McCarroll SA; Holmans P; Owen MJ; O'Donovan MC
    Transl Psychiatry; 2015 Jul; 5(7):e607. PubMed ID: 26196440
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Whole-genome sequencing of monozygotic twins discordant for schizophrenia indicates multiple genetic risk factors for schizophrenia.
    Tang J; Fan Y; Li H; Xiang Q; Zhang DF; Li Z; He Y; Liao Y; Wang Y; He F; Zhang F; Shugart YY; Liu C; Tang Y; Chan RCK; Wang CY; Yao YG; Chen X
    J Genet Genomics; 2017 Jun; 44(6):295-306. PubMed ID: 28645778
    [TBL] [Abstract][Full Text] [Related]  

  • 20. De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability.
    McCarthy SE; Gillis J; Kramer M; Lihm J; Yoon S; Berstein Y; Mistry M; Pavlidis P; Solomon R; Ghiban E; Antoniou E; Kelleher E; O'Brien C; Donohoe G; Gill M; Morris DW; McCombie WR; Corvin A
    Mol Psychiatry; 2014 Jun; 19(6):652-8. PubMed ID: 24776741
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.